PMID- 29888774
OWN - NLM
STAT- MEDLINE
DCOM- 20190124
LR  - 20190124
IS  - 2040-3372 (Electronic)
IS  - 2040-3364 (Linking)
VI  - 10
IP  - 24
DP  - 2018 Jun 21
TI  - The light-up fluorescence of AgNCs in a "DNA bulb".
PG  - 11517-11523
LID - 10.1039/c8nr02575d [doi]
AB  - In this presented work, a series of designs and experiments have been constructed 
      to study how a DNA structure affected the fluorescence of silver nanoclusters 
      (AgNCs). A "bulb"-like DNA structure was firstly used as the synthesizing 
      template, and bright green-emitting AgNCs were obtained with a quantum yield of 
      17.2%. The "DNA bulb" structure was assembled using three single-stranded 
      oligonucleotides (ssDNAs), with a flexible ssDNA part serving as the "filament". 
      The results seemed intriguing as luminous AgNCs could be obtained only when the 
      complete spatial structure was formed. To further investigate the role of the 
      "bulb" structure, thirteen cytosine-rich sequences were employed as the 
      "filament", respectively. Interestingly, the fluorescence intensities of AgNCs 
      were all enhanced after the "filament" ssDNA was integrated into the "bulb" 
      structure. The enhancement was as much as 175.2-fold, and the minimum enhancement 
      was 1.3-fold. Spectral analyses were then conducted to give an understanding of 
      the role of cytosine. When the sequences in the "bulb shell" were changed, the 
      "DNA bulb" structure still showed an enhancing effect. Finally, the 
      green-emitting AgNCs were utilized toward the selective detection of Hg2+ to 
      demonstrate potential applications.
FAU - Guo, Yahui
AU  - Guo Y
AD  - State Key Laboratory of Food Science and Technology, School of Food Science and 
      Technology, Jiangnan University, Lihu Avenue, Wuxi 214122, China.
FAU - Shen, Fumiao
AU  - Shen F
FAU - Cheng, Yuliang
AU  - Cheng Y
FAU - Xie, Yunfei
AU  - Xie Y
FAU - Yu, Hang
AU  - Yu H
FAU - Yao, Weirong
AU  - Yao W
FAU - Li, Hung-Wing
AU  - Li HW
FAU - Qian, He
AU  - Qian H
FAU - Pei, Renjun
AU  - Pei R
LA  - eng
PT  - Journal Article
PL  - England
TA  - Nanoscale
JT  - Nanoscale
JID - 101525249
RN  - 0 (DNA, Single-Stranded)
RN  - 0 (Oligonucleotides)
RN  - 3M4G523W1G (Silver)
RN  - FXS1BY2PGL (Mercury)
SB  - IM
MH  - DNA, Single-Stranded/*chemistry
MH  - *Fluorescence
MH  - Mercury/analysis
MH  - Metal Nanoparticles/*chemistry
MH  - Oligonucleotides/chemistry
MH  - *Silver
MH  - Spectrometry, Fluorescence
EDAT- 2018/06/12 06:00
MHDA- 2019/01/25 06:00
CRDT- 2018/06/12 06:00
PHST- 2018/06/12 06:00 [pubmed]
PHST- 2019/01/25 06:00 [medline]
PHST- 2018/06/12 06:00 [entrez]
AID - 10.1039/c8nr02575d [doi]
PST - ppublish
SO  - Nanoscale. 2018 Jun 21;10(24):11517-11523. doi: 10.1039/c8nr02575d.