PMID- 29893336 OWN - NLM STAT- MEDLINE DCOM- 20181101 LR - 20220317 IS - 1998-4138 (Electronic) IS - 1998-4138 (Linking) VI - 14 IP - 3 DP - 2018 Apr-Jun TI - Application of bi-nanoparticle on dose enhancement effect in two different polymer gel dosimeter using spectrophotometer. PG - 662-665 LID - 10.4103/0973-1482.187295 [doi] AB - PURPOSE: This study aimed at proving the ability of bismuth-nanoparticle (Bi-np) in dose enhancement effect (DEE) using the polymer gel dosimeter. Two different polymer gels, namely poly acrylamide gelatin tetrakis hydroxymethyl phosphonium chloride (PAGAT) and N-isopropylacrylamide (NIPAM) gels were chosen for this study. MATERIALS AND METHODS: The gels were doped with Bi-np particle with various concentrations of 0.5 mM, 1 mM, and 2.5 mM and were then irradiated with a CO-60 gamma radiation source of energy 1.25 MeV. Gel samples were analyzed by spectrophotometer. The dose enhancement factor (DEF) was calculated for both gels for all concentrations of Bi-np particle. RESULTS: The higher DEF for PAGAT and NIPAM was calculated as 1.3415 and 1.1823, respectively, for 0.5 mM concentration of Bi-np. CONCLUSION: From our results, we infer that 0.5 mM is the optimal concentration in polymer gel to obtain good DEEs in the energy range of 1.25 MeV. FAU - Sathiyaraj, P AU - Sathiyaraj P AD - Department of Physics, Medical Dosimetry Laboratory, School of Advanced Sciences, VIT-University, Vellore, Tamil Nadu, India. FAU - Jebaseelan Samuel, E James AU - Jebaseelan Samuel EJ AD - Photonics, Nuclear and Medical Physics Division, VIT University, Vellore, Tamil Nadu, India. LA - eng PT - Journal Article PL - India TA - J Cancer Res Ther JT - Journal of cancer research and therapeutics JID - 101249598 RN - 0 (Acrylamides) RN - 0 (Acrylic Resins) RN - 0 (Gels) RN - 0 (Polymers) RN - 9000-70-8 (Gelatin) RN - 9003-05-8 (polyacrylamide) RN - B7GFF17L9U (N-isopropylacrylamide) SB - IM MH - Acrylamides/chemistry MH - Acrylic Resins/chemistry MH - Dose-Response Relationship, Radiation MH - Gelatin/chemistry MH - *Gels MH - Humans MH - Nanoparticles/*chemistry MH - *Phantoms, Imaging MH - Polymers/*chemistry MH - Radiometry/*instrumentation/*methods MH - Spectrophotometry/*methods OTO - NOTNLM OT - Dose enhancements OT - N-isopropylacrylamide OT - poly acrylamide gelatin tetrakis hydroxymethyl phosphonium chloride OT - spectrophotometer COIS- There are no conflicts of interest EDAT- 2018/06/13 06:00 MHDA- 2018/11/02 06:00 CRDT- 2018/06/13 06:00 PHST- 2018/06/13 06:00 [entrez] PHST- 2018/06/13 06:00 [pubmed] PHST- 2018/11/02 06:00 [medline] AID - JCanResTher_2018_14_3_662_187295 [pii] AID - 10.4103/0973-1482.187295 [doi] PST - ppublish SO - J Cancer Res Ther. 2018 Apr-Jun;14(3):662-665. doi: 10.4103/0973-1482.187295.