PMID- 29895011 OWN - NLM STAT- MEDLINE DCOM- 20181012 LR - 20181012 IS - 1423-0267 (Electronic) IS - 0030-3755 (Linking) VI - 240 IP - 3 DP - 2018 TI - Incidence of Macular Holes in the Fellow Eye without Vitreomacular Detachment at Baseline. PG - 135-142 LID - 10.1159/000488956 [doi] AB - PURPOSE: To determine the rate of macular holes (MH) occurring in the fellow eyes of eyes with MH depending on the vitreomacular interface at baseline. METHODS: This was a retrospective study of patients operated on for idiopathic MH, with persistent vitreofoveal attachment in the fellow eye assessed by spectral-domain optical coherence tomography (SD-OCT). Follow-up lasted 6 months or more, and the main outcome was the occurrence of an MH. RESULTS: The 77 fellow eyes included had a mean follow-up of 34.11 +/- 22.3 months (6-78.4). At baseline, 31 eyes had vitreomacular traction (VMT), 35 vitreomacular adhesion, and 11 no posterior vitreous detachment. MH occurred in 19.5% of the cases (15/77). The rate of MH was significantly higher among the eyes with VMT than among the eyes without VMT at baseline (35.5 vs. 8.7%; p = 0.009). CONCLUSION: One-third of eyes with VMT at baseline identified by SD-OCT will develop an MH in the following 5 years. CI - (c) 2018 S. Karger AG, Basel. FAU - Philippakis, Elise AU - Philippakis E FAU - Astroz, Polina AU - Astroz P FAU - Tadayoni, Ramin AU - Tadayoni R FAU - Gaudric, Alain AU - Gaudric A LA - eng PT - Journal Article DEP - 20180612 PL - Switzerland TA - Ophthalmologica JT - Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde JID - 0054655 SB - IM MH - Aged MH - Aged, 80 and over MH - Cell Adhesion MH - Female MH - Humans MH - Incidence MH - Macula Lutea/metabolism MH - Male MH - Middle Aged MH - Retinal Detachment/*complications MH - Retinal Perforations/diagnostic imaging/*epidemiology/surgery MH - Retrospective Studies MH - Risk Factors MH - Tomography, Optical Coherence MH - Vitreous Body/metabolism MH - Vitreous Detachment/*complications OTO - NOTNLM OT - Fellow eye OT - Macular hole OT - Posterior vitreous detachment OT - Spectral-domain optical coherence tomography OT - Vitreomacular adhesion OT - Vitreomacular traction EDAT- 2018/06/13 06:00 MHDA- 2018/10/13 06:00 CRDT- 2018/06/13 06:00 PHST- 2017/12/12 00:00 [received] PHST- 2018/04/03 00:00 [accepted] PHST- 2018/06/13 06:00 [pubmed] PHST- 2018/10/13 06:00 [medline] PHST- 2018/06/13 06:00 [entrez] AID - 000488956 [pii] AID - 10.1159/000488956 [doi] PST - ppublish SO - Ophthalmologica. 2018;240(3):135-142. doi: 10.1159/000488956. Epub 2018 Jun 12.