PMID- 29895272 OWN - NLM STAT- MEDLINE DCOM- 20190702 LR - 20240318 IS - 1471-2458 (Electronic) IS - 1471-2458 (Linking) VI - 18 IP - 1 DP - 2018 Jun 13 TI - Association between sleep duration and metabolic syndrome: a cross-sectional study. PG - 720 LID - 10.1186/s12889-018-5557-8 [doi] LID - 720 AB - BACKGROUND: Both short and long sleep duration have been consistently studied as a risk factor for obesity, hyperglycemia and hypertension. In this cross-sectional study, we provide an updated analysis of the Health Examinees (HEXA) study on the association between sleep duration and metabolic syndrome (MetS) occurrence among Koreans age 40-69 year olds. METHODS: A total of 133,608 subjects (44,930 men, 88,678 women) were enrolled in the HEXA study 2004-2013. Sleep duration was categorized into 4 sleep categories (< 6 h, 6 to < 8 h, 8 to < 10 h, >/=10 h). MetS criterion was based on the National Cholesterol Education Program, Adult Treatment Panel III. Logistic regression was used to calculate adjusted odds ratios (ORs) and 95% confidence intervals (CIs). RESULTS: Compared with individuals sleeping 6 to < 8 h per day, less than 6 h of sleep was associated with MetS (multivariable adjusted OR: 1.12, 95% CI: 1.05-1.19) and elevated waist circumference (1.15, 1.08-1.23) among men; with elevated waist circumference (1.09, 1.04-1.14) among women. Greater than 10 h of sleep was associated with MetS (1.28, 1.08-1.50) and elevated triglycerides (1.33, 1.14-1.56) among men; with MetS (1.40, 1.24-1.58), elevated waist circumference (1.14, 1.02-1.27), elevated triglycerides (1.41, 1.25-1.58), reduced high-density lipoprotein cholesterol (HDL-C) (1.24, 1.12-1.38), and elevated fasting glucose (1.39, 1.23-1.57) among women. CONCLUSIONS: Less than 6 h of sleep is associated with elevated waist circumference among both men and women and with MetS among men only. Greater than 10 h of sleep is associated with MetS and elevated triglycerides among both men and women and with elevated waist circumference, reduced HDL-C, and elevated fasting glucose among women only. FAU - Kim, Claire E AU - Kim CE AD - Department of Preventive Medicine, Seoul National University College of Medicine, 102 Daehak-ro, Jongno-gu, Seoul, 03080, Korea. AD - Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea. FAU - Shin, Sangah AU - Shin S AD - Department of Food and Nutrition, Chung-Ang University, Seoul, Gyeonggi-do, 17546, Korea. FAU - Lee, Hwi-Won AU - Lee HW AD - Department of Preventive Medicine, Seoul National University College of Medicine, 102 Daehak-ro, Jongno-gu, Seoul, 03080, Korea. AD - Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea. FAU - Lim, Jiyeon AU - Lim J AD - Department of Preventive Medicine, Seoul National University College of Medicine, 102 Daehak-ro, Jongno-gu, Seoul, 03080, Korea. FAU - Lee, Jong-Koo AU - Lee JK AD - JW Lee Center for Global Medicine, Seoul National University College of Medicine, Seoul, Korea. AD - Department of Family Medicine, Seoul National University Hospital, Seoul, Korea. FAU - Shin, Aesun AU - Shin A AD - Department of Preventive Medicine, Seoul National University College of Medicine, 102 Daehak-ro, Jongno-gu, Seoul, 03080, Korea. FAU - Kang, Daehee AU - Kang D AUID- ORCID: 0000-0003-4031-5878 AD - Department of Preventive Medicine, Seoul National University College of Medicine, 102 Daehak-ro, Jongno-gu, Seoul, 03080, Korea. dhkang@snu.ac.kr. AD - Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea. dhkang@snu.ac.kr. AD - Institute of Environmental Medicine, Seoul National University Medical Research Center, Seoul, Korea. dhkang@snu.ac.kr. LA - eng GR - 2004-E71004-00; 2005-E71011-00; 2005-E71009-00; 2006-E71001-00; 2006-E71004-00; 2006-E71010-00; 2006- E71003-00; 2007-E71004-00; 2007-E71006-00; 2008-E71006- 00; 2008-E71008-00; 2009-E71009-00; 2010-E71006-00; 2011- E71006-00; 2012-E71001-00; 2013-E71009-00/Korea Centers for Disease Control & Prevention/International PT - Journal Article DEP - 20180613 PL - England TA - BMC Public Health JT - BMC public health JID - 100968562 RN - 0 (Cholesterol, HDL) SB - IM MH - Adult MH - Cholesterol, HDL/blood MH - Cross-Sectional Studies MH - Female MH - Humans MH - Hypertension/epidemiology MH - Hypertriglyceridemia/epidemiology MH - Logistic Models MH - Male MH - Metabolic Syndrome/blood/*epidemiology MH - Middle Aged MH - Obesity/blood/*epidemiology MH - Odds Ratio MH - Risk Factors MH - Sleep Deprivation/blood/*epidemiology MH - Waist Circumference PMC - PMC5998453 OTO - NOTNLM OT - Diabetes OT - Epidemiology OT - Metabolic disorder OT - Metabolic syndrome OT - Sleep duration COIS- ETHICS APPROVAL AND CONSENT TO PARTICIPATE: The HEXA study protocol was approved by the Institutional Review Board (IRB) of the Seoul National University Hospital, Seoul, Korea (IRB number 0608-018- 179) and the Korea National Institute of Health (IRB number 2014-08-02-3C-A). All study participants gave written informed consent prior to entering the study. COMPETING INTERESTS: The authors declare that they have no competing interests. PUBLISHER'S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. EDAT- 2018/06/14 06:00 MHDA- 2019/07/03 06:00 PMCR- 2018/06/13 CRDT- 2018/06/14 06:00 PHST- 2017/06/29 00:00 [received] PHST- 2018/05/10 00:00 [accepted] PHST- 2018/06/14 06:00 [entrez] PHST- 2018/06/14 06:00 [pubmed] PHST- 2019/07/03 06:00 [medline] PHST- 2018/06/13 00:00 [pmc-release] AID - 10.1186/s12889-018-5557-8 [pii] AID - 5557 [pii] AID - 10.1186/s12889-018-5557-8 [doi] PST - epublish SO - BMC Public Health. 2018 Jun 13;18(1):720. doi: 10.1186/s12889-018-5557-8.