PMID- 29901460 OWN - NLM STAT- MEDLINE DCOM- 20190617 LR - 20190617 IS - 1531-7072 (Electronic) IS - 1070-5295 (Linking) VI - 24 IP - 4 DP - 2018 Aug TI - Mechanical circulatory devices in acute heart failure. PG - 286-291 LID - 10.1097/MCC.0000000000000520 [doi] AB - PURPOSE OF REVIEW: Temporary circulatory support (TCS) with short-term mechanical circulatory support (MCS) devices is increasingly used as a salvage therapy for patients with refractory cardiogenic shock. This article provides an overview of current devices, their indications and management, and discusses results of recent case series and trials. RECENT FINDINGS: Percutaneous active MCS devices (Impella, TandemHeart...) and venoarterial extracorporeal membrane oxygenation (VA-ECMO) are utilized as a bridge to 'decision' that includes weaning after cardiac function recovery, transplantation, long-term MCS and withdrawal in case of futility. VA-ECMO is considered the first-line TCS since it allows rapid improvement in oxygenation, is less expensive, and is also suitable for patients with biventricular failure. Combining Impella or intra-aortic balloon pump support with ECMO might decrease left ventricular pressure and improve outcomes. Sepsis-associated cardiomyopathy, massive pulmonary embolism, arrhythmic storm and Takotsubo-like cardiomyopathy are among emerging indications for TCS. SUMMARY: TCS have become the cornerstone of the management of patients with cardiogenic shock, although the evidence supporting their efficacy is limited. VA-ECMO is considered the first-line option, with a growing number of accepted and emerging indications. Randomized clinical trials are now needed to determine the respective place of different MCS devices in cardiogenic shock treatment strategies. FAU - Pineton de Chambrun, Marc AU - Pineton de Chambrun M AD - Service de Medecine Intensive-Reanimation, Institut de Cardiologie, APHP Hopital Pitie-Salpetriere. AD - Sorbonne Universite, INSERM, UMRS_1166-ICAN, Institute of Cardiometabolism and Nutrition, Paris, France. FAU - Brechot, Nicolas AU - Brechot N AD - Service de Medecine Intensive-Reanimation, Institut de Cardiologie, APHP Hopital Pitie-Salpetriere. AD - Sorbonne Universite, INSERM, UMRS_1166-ICAN, Institute of Cardiometabolism and Nutrition, Paris, France. FAU - Combes, Alain AU - Combes A AD - Service de Medecine Intensive-Reanimation, Institut de Cardiologie, APHP Hopital Pitie-Salpetriere. AD - Sorbonne Universite, INSERM, UMRS_1166-ICAN, Institute of Cardiometabolism and Nutrition, Paris, France. LA - eng PT - Journal Article PT - Review PL - United States TA - Curr Opin Crit Care JT - Current opinion in critical care JID - 9504454 SB - IM MH - Assisted Circulation/*methods MH - *Critical Care MH - Extracorporeal Membrane Oxygenation MH - Health Services Needs and Demand MH - Heart Failure/physiopathology/*therapy MH - Humans MH - Intra-Aortic Balloon Pumping MH - Practice Guidelines as Topic MH - Randomized Controlled Trials as Topic MH - Shock, Cardiogenic/physiopathology/*therapy MH - Time Factors EDAT- 2018/06/15 06:00 MHDA- 2019/06/18 06:00 CRDT- 2018/06/15 06:00 PHST- 2018/06/15 06:00 [pubmed] PHST- 2019/06/18 06:00 [medline] PHST- 2018/06/15 06:00 [entrez] AID - 10.1097/MCC.0000000000000520 [doi] PST - ppublish SO - Curr Opin Crit Care. 2018 Aug;24(4):286-291. doi: 10.1097/MCC.0000000000000520.