PMID- 29903200
OWN - NLM
STAT- MEDLINE
DCOM- 20181127
LR  - 20181127
IS  - 1000-8020 (Print)
IS  - 1000-8020 (Linking)
VI  - 46
IP  - 6
DP  - 2017 Nov
TI  - [Interaction between alcohol-drinking and other factors of lifestyles on the risk 
      of type 2 diabetes mellitus].
PG  - 918-929
AB  - OBJECTIVE: To explore the interaction between alcohol-drinking and other factors 
      of lifestyles on the risk of type 2 diabetes mellitus( T2 DM). METHODS: From 
      June2015 to February 2016, 320 patients diagnosed with T2 DM in Huainan Eastern 
      Hospital and 640 healthy cases at the same time in local medical examination 
      center were randomlychosen to carry out the investigation, the differences 
      between the two groups about demography, alcohol-drinking, smoking, physical 
      activities and dietary habits were compared. Non-conditional logistic regression 
      and generalized multifactor dimensionality reduction( GMDR) were used for 
      statistical analysis. RESULTS: ( 1) Data from logistic regression analysis showed 
      that after adjusting confounding factors, compared with Q1, the intake marks of 
      grains( OR = 0. 310, 95% CI 0. 153-0. 628), vegetables-fruits( OR =0. 444, 95% CI 
      0. 245-0. 806), milk or dairy products( OR = 0. 510, 95% CI 0. 329-0. 790), 
      beans( OR = 0. 434, 95% CI 0. 212-0. 901), red meat( OR = 0. 461, 95% CI0. 229-0. 
      926), western food( OR = 0. 223, 95% CI 0. 076-0. 652), sugary drinks( OR = 0. 
      150, 95% CI 0. 035-0. 643) were Q5 and the BMI less than 24. 0( OR =0. 189, 95% 
      CI 0. 109-0. 329) were protective factors of T2 DM. However, frequent drinking( 
      OR = 3. 936, 95% CI 1. 145-8. 734) and moderate physical activities which were 
      equal to or more than five times per week( OR = 1. 558, 95% CI 1. 013-2. 876)were 
      risk factors of T2 DM. There were multiplied interaction between frequent 
      drinking and intake of grains( Q5)( OR = 0. 852, 95% CI 0. 765-0. 949) or 
      vegetables-fruits( Q5)( OR = 0. 862, 95% CI 0. 757-0. 982) or adequate moderate 
      physical activities( OR = 0. 613, 95% CI 0. 468-0. 803). There were additive 
      interactions between frequent drinking and high intake of red meat or sugary 
      drinks or adequate moderate physical activities. GMDR analysis showed that 
      interaction among sugary drinks, red meat and frequent drinking on the risk of T2 
      DM may exist( P = 0. 001). CONCLUSION: Frequent drinking and some other 
      controllable factors have combined effect to increase the risk of T2 DM.
FAU - Xue, Song
AU  - Xue S
AD  - Medicine College, Anhui University of Science and Technology, Huainan 232001, 
      China.
FAU - Mu, Min
AU  - Mu M
AD  - Medicine College, Anhui University of Science and Technology, Huainan 232001, 
      China.
FAU - Li, Wenyue
AU  - Li W
AD  - Medicine College, Anhui University of Science and Technology, Huainan 232001, 
      China.
FAU - Fang, Kehong
AU  - Fang K
AD  - Medicine College, Anhui University of Science and Technology, Huainan 232001, 
      China.
FAU - Shang, Jie
AU  - Shang J
AD  - Medicine College, Anhui University of Science and Technology, Huainan 232001, 
      China.
FAU - Liu, Kai
AU  - Liu K
AD  - Medicine College, Anhui University of Science and Technology, Huainan 232001, 
      China.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Wei Sheng Yan Jiu
JT  - Wei sheng yan jiu = Journal of hygiene research
JID - 9426367
SB  - IM
MH  - Alcohol Drinking/blood/*epidemiology
MH  - Diabetes Mellitus, Type 2/*epidemiology
MH  - *Diet
MH  - *Feeding Behavior
MH  - Female
MH  - Glucose Intolerance/*epidemiology
MH  - Humans
MH  - *Life Style
MH  - Male
MH  - Risk Factors
MH  - Vegetables
OTO - NOTNLM
OT  - alcohol-drinking
OT  - diet
OT  - interaction
OT  - physical activity
OT  - type 2 diabetes mellitus
EDAT- 2018/06/16 06:00
MHDA- 2018/11/28 06:00
CRDT- 2018/06/16 06:00
PHST- 2018/06/16 06:00 [entrez]
PHST- 2018/06/16 06:00 [pubmed]
PHST- 2018/11/28 06:00 [medline]
PST - ppublish
SO  - Wei Sheng Yan Jiu. 2017 Nov;46(6):918-929.