PMID- 29903682
OWN - NLM
STAT- MEDLINE
DCOM- 20190726
LR  - 20190726
IS  - 1532-8422 (Electronic)
IS  - 1053-0770 (Linking)
VI  - 32
IP  - 6
DP  - 2018 Dec
TI  - Impact of Obesity on Noninvasive Cardiac Hemodynamic Measurement by Electrical 
      Cardiometry in Adults With Aortic Stenosis.
PG  - 2505-2511
LID - S1053-0770(18)30271-4 [pii]
LID - 10.1053/j.jvca.2018.04.040 [doi]
AB  - OBJECTIVES: There are substantial potential benefits to noninvasive cardiac 
      monitoring methods, such as electrical cardiometry (EC), over more invasive 
      methods, including significantly reduced risk of complications, lower up-front 
      and operational costs, ease of use, and continuous monitoring. To take advantage 
      of these technologies, clinical equivalence to currently established methods must 
      be determined. The authors sought to determine if the noninvasive measurement of 
      cardiac index (CI) by EC was clinically equivalent to thermodilution (TD) in 
      adult patients with aortic stenosis (AS). DESIGN: This is a cross-sectional study 
      comparing measurement devices in a single patient group. SETTING: Single-center, 
      university teaching hospital. PARTICIPANTS: The study included 52 adult patients 
      with aortic stenosis undergoing right heart catheterization. INTERVENTIONS: 
      Cardiac output (CO) was measured concurrently using EC with an ICON device and TD 
      in 52 participants with AS. CI values were to determine the accuracy and 
      precision of EC in reference to TD. Percentage error (PE) was used to assess 
      their clinical equivalence. The participants were divided further into groups 
      (normal and overweight/obese) based on body mass index and the analysis was 
      repeated. MEASUREMENTS AND MAIN RESULTS: CO measurement made by EC in adult 
      patients with obesity or overweight was reduced significantly relative to TD. 
      This was not observed in normal-weight adult AS patients. EC provided clinically 
      equivalent measurements to TD for measuring CI in normal-weight adult AS patients 
      (PE = 25.0%), but not for those adult AS patients with overweight or obesity (PE 
      = 42.3%). CONCLUSION: Overall, the ICON device produced lower CO and index 
      measurements relative to TD in adult patients with AS. Overweight and obesity 
      also significantly affected the relative precision and accuracy of the ICON 
      electrical cardiometric device to measure CI in these patients.
CI  - Copyright (c) 2018 Elsevier Inc. All rights reserved.
FAU - Teefy, Patrick
AU  - Teefy P
AD  - Department of Paediatrics, Division of Paediatric Cardiology, Western University, 
      London, Canada.
FAU - Bagur, Rodrigo
AU  - Bagur R
AD  - Department of Paediatrics, Division of Paediatric Cardiology, Western University, 
      London, Canada.
FAU - Phillips, Chantal
AU  - Phillips C
AD  - Department of Paediatrics, Division of Paediatric Cardiology, Western University, 
      London, Canada.
FAU - Karimi-Shahri, Kourosh
AU  - Karimi-Shahri K
AD  - Department of Paediatrics, Division of Paediatric Cardiology, Western University, 
      London, Canada.
FAU - Teefy, John
AU  - Teefy J
AD  - Department of Paediatrics, Division of Paediatric Cardiology, Western University, 
      London, Canada.
FAU - Sule, Raksha
AU  - Sule R
AD  - Department of Paediatrics, Division of Paediatric Cardiology, Western University, 
      London, Canada.
FAU - Dempsey, Adam A
AU  - Dempsey AA
AD  - Department of Paediatrics, Division of Paediatric Cardiology, Western University, 
      London, Canada; Children's Health Research Institute, London, Canada; Paediatric 
      Cardiopulmonary Research Laboratory, London Health Sciences Centre, London, 
      Canada.
FAU - Norozi, Kambiz
AU  - Norozi K
AD  - Department of Paediatrics, Division of Paediatric Cardiology, Western University, 
      London, Canada; Children's Health Research Institute, London, Canada; Paediatric 
      Cardiopulmonary Research Laboratory, London Health Sciences Centre, London, 
      Canada; Department of Paediatric Cardiology and Intensive Care Medicine, Hannover 
      Medical School, Hannover, Germany; Department of Paediatric Cardiology and 
      Intensive Care Medicine, University of Goettingen, Goettingen, Germany. 
      Electronic address: kambiz.norozi@lhsc.on.ca.
LA  - eng
PT  - Journal Article
DEP - 20180426
PL  - United States
TA  - J Cardiothorac Vasc Anesth
JT  - Journal of cardiothoracic and vascular anesthesia
JID - 9110208
MH  - Aged
MH  - Aortic Valve Stenosis/complications/diagnosis/*physiopathology
MH  - Blood Flow Velocity/physiology
MH  - Cardiac Catheterization/*methods
MH  - Cardiac Output/physiology
MH  - Cross-Sectional Studies
MH  - Electric Impedance
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Obesity/*complications/physiopathology
MH  - Reproducibility of Results
MH  - Retrospective Studies
MH  - Systole
MH  - Thermodilution/methods
OTO - NOTNLM
OT  - aortic valve stenosis
OT  - bioimpedance
OT  - cardiac output
OT  - electrical cardiometry
OT  - obesity
OT  - thermodilution
EDAT- 2018/06/16 06:00
MHDA- 2019/07/28 06:00
CRDT- 2018/06/16 06:00
PHST- 2018/02/20 00:00 [received]
PHST- 2018/06/16 06:00 [pubmed]
PHST- 2019/07/28 06:00 [medline]
PHST- 2018/06/16 06:00 [entrez]
AID - S1053-0770(18)30271-4 [pii]
AID - 10.1053/j.jvca.2018.04.040 [doi]
PST - ppublish
SO  - J Cardiothorac Vasc Anesth. 2018 Dec;32(6):2505-2511. doi: 
      10.1053/j.jvca.2018.04.040. Epub 2018 Apr 26.