PMID- 29906421
OWN - NLM
STAT- MEDLINE
DCOM- 20190708
LR  - 20191210
IS  - 1532-821X (Electronic)
IS  - 0003-9993 (Linking)
VI  - 99
IP  - 11
DP  - 2018 Nov
TI  - Effectiveness of Pulmonary Rehabilitation in Patients With Chronic Obstructive 
      Pulmonary Disease With Different Degrees of Static Lung Hyperinflation.
PG  - 2279-2286.e3
LID - S0003-9993(18)30358-7 [pii]
LID - 10.1016/j.apmr.2018.05.011 [doi]
AB  - OBJECTIVE: To evaluate the effect of pulmonary rehabilitation (PR) on exercise 
      performance and quality of life in patients with chronic obstructive pulmonary 
      disease (COPD) with different degrees of static lung hyperinflation (LH). DESIGN: 
      Retrospective cohort study. SETTING: PR network. PARTICIPANTS: A cohort of 1981 
      patients with COPD (55% men; age: 66.8+/-9.3y; forced expiratory volume in the 
      first second%: 50.7+/-19.5; residual volume [RV]%: 163.0+/-49.7). INTERVENTION: An 
      interdisciplinary PR program for patients with COPD consisting of 40 sessions. 
      MAIN OUTCOME MEASURES: Participants were stratified into 5 quintiles according to 
      baseline RV and were evaluated on the basis of pre- and post-PR 6-minute walk 
      distance (6MWD), constant work rate test (CWRT), and Saint George's Respiratory 
      Questionnaire (SGRQ), among other clinical parameters. RESULTS: With increasing 
      RV quintile, patients were younger, more frequently women, had lower forced 
      expiratory volume in the first second%, lower body mass index and fat-free mass 
      index, shorter 6MWD, shorter CWRT, and worse SGRQ scores (P<.01). All RV strata 
      improved after PR in all 3 outcomes (P<.001). Nevertheless, higher, compared to 
      lower RV categories, had lower DeltaCWRT (P<.01) but similar Delta6MWD (P=.948) and DeltaSGRQ 
      (P=.086) after PR. CONCLUSIONS: LH in COPD is related to younger age, female sex, 
      lower body weight, worse exercise capacity and health status, but did not prevent 
      patients from benefitting from PR. LH, however, influences walking and cycling 
      response after PR differently.
CI  - Copyright (c) 2018 American Congress of Rehabilitation Medicine. Published by 
      Elsevier Inc. All rights reserved.
FAU - Vanfleteren, Michiel J
AU  - Vanfleteren MJ
AD  - Department of Research and Education, Center of Expertise for Chronic Organ 
      Failure (CIRO), Horn, the Netherlands; Department of Respiratory Medicine, 
      Maastricht University Medical Centre (MUMC+), Maastricht, the Netherlands. 
      Electronic address: michielvanfleteren@msn.com.
FAU - Koopman, Maud
AU  - Koopman M
AD  - Department of Research and Education, Center of Expertise for Chronic Organ 
      Failure (CIRO), Horn, the Netherlands.
FAU - Spruit, Martijn A
AU  - Spruit MA
AD  - Department of Research and Education, Center of Expertise for Chronic Organ 
      Failure (CIRO), Horn, the Netherlands.
FAU - Pennings, Herman-Jan
AU  - Pennings HJ
AD  - Department of Respiratory Medicine, St. Laurentius Hospital, Roermond, the 
      Netherlands.
FAU - Smeenk, Frank
AU  - Smeenk F
AD  - Department of Respiratory Medicine, Catharina Hospital, Eindhoven, the 
      Netherlands.
FAU - Pieters, Willem
AU  - Pieters W
AD  - Department of Respiratory Medicine, Elkerliek Hospital, Helmond, the Netherlands.
FAU - van den Bergh, Jan J
AU  - van den Bergh JJ
AD  - Department of Respiratory Medicine, St. Jans Gasthuis, Weert, the Netherlands.
FAU - Michels, Arent-Jan
AU  - Michels AJ
AD  - Department of Respiratory Medicine, St Anna Hospital, Geldrop, the Netherlands.
FAU - Wouters, Emiel F
AU  - Wouters EF
AD  - Department of Research and Education, Center of Expertise for Chronic Organ 
      Failure (CIRO), Horn, the Netherlands; Department of Respiratory Medicine, 
      Maastricht University Medical Centre (MUMC+), Maastricht, the Netherlands.
FAU - Groenen, Miriam T
AU  - Groenen MT
AD  - Department of Research and Education, Center of Expertise for Chronic Organ 
      Failure (CIRO), Horn, the Netherlands.
FAU - Franssen, Frits M
AU  - Franssen FM
AD  - Department of Research and Education, Center of Expertise for Chronic Organ 
      Failure (CIRO), Horn, the Netherlands; Department of Respiratory Medicine, 
      Maastricht University Medical Centre (MUMC+), Maastricht, the Netherlands.
FAU - Vanfleteren, Lowie E
AU  - Vanfleteren LE
AD  - Department of Research and Education, Center of Expertise for Chronic Organ 
      Failure (CIRO), Horn, the Netherlands; Department of Respiratory Medicine, 
      Maastricht University Medical Centre (MUMC+), Maastricht, the Netherlands; COPD 
      Center, Sahlgrenska University Hospital, Goteborg, Sweden.
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
DEP - 20180612
PL  - United States
TA  - Arch Phys Med Rehabil
JT  - Archives of physical medicine and rehabilitation
JID - 2985158R
SB  - IM
MH  - Aged
MH  - Female
MH  - Forced Expiratory Volume
MH  - Humans
MH  - Hyperventilation/etiology/physiopathology/*rehabilitation
MH  - Lung/physiopathology
MH  - Male
MH  - Middle Aged
MH  - Pulmonary Disease, Chronic 
      Obstructive/complications/physiopathology/*rehabilitation
MH  - Residual Volume
MH  - Respiratory Function Tests
MH  - Respiratory Therapy/*methods
MH  - Retrospective Studies
MH  - Treatment Outcome
MH  - Walk Test
MH  - Walking
OTO - NOTNLM
OT  - COPD
OT  - Rehabilitation
EDAT- 2018/06/16 06:00
MHDA- 2019/07/10 06:00
CRDT- 2018/06/16 06:00
PHST- 2017/10/04 00:00 [received]
PHST- 2018/03/31 00:00 [revised]
PHST- 2018/05/07 00:00 [accepted]
PHST- 2018/06/16 06:00 [pubmed]
PHST- 2019/07/10 06:00 [medline]
PHST- 2018/06/16 06:00 [entrez]
AID - S0003-9993(18)30358-7 [pii]
AID - 10.1016/j.apmr.2018.05.011 [doi]
PST - ppublish
SO  - Arch Phys Med Rehabil. 2018 Nov;99(11):2279-2286.e3. doi: 
      10.1016/j.apmr.2018.05.011. Epub 2018 Jun 12.