PMID- 29915975
OWN - NLM
STAT- MEDLINE
DCOM- 20190415
LR  - 20190415
IS  - 1435-604X (Electronic)
IS  - 0268-8921 (Linking)
VI  - 33
IP  - 9
DP  - 2018 Dec
TI  - Efficacy assessment of UVA1 and narrowband UVB for treatment of scalp psoriasis.
PG  - 1979-1982
LID - 10.1007/s10103-018-2564-z [doi]
AB  - To compare the efficacy and safety of UVA1 and narrowband UVB (NB-UVB) therapy in 
      the treatment of scalp psoriasis. Patients with scalp psoriasis were randomly 
      assigned to either UVA1 or NB-UVB therapy. Both treatments were performed three 
      times weekly for 6 weeks. Clinical efficacy was evaluated by using Psoriasis 
      Scalp Severity Index (PSSI), and patient-reported quality of life (QoL) was 
      assessed by Dermatology Life Quality Index (DLQI). Totally 68 patients completed 
      the study. Both UVA1 and NB-UVB phototherapy achieved a statistically significant 
      reduction of PSSI and DLQI scores at the end of the treatment period. Compared 
      with the NB-UVB group, the significantly greater improvements occurred in UVA1 
      treatment group at week 3, although differences declined thereafter through week 
      10. Both UVA1 and NB-UVB therapy were well-tolerated in this study, and the 
      occurrence of adverse events (AEs) was uncommon. Both UVA1 and NB-UVB 
      phototherapy could offer relief of scalp symptoms in patients with scalp 
      involvement. Furthermore, UVA1 treatment could improve the clinical 
      manifestations and QoL more quickly than NB-UVB therapy.
FAU - Zhou, Jing
AU  - Zhou J
AD  - Department of Dermatology, Shanghai Skin Disease Hospital, Shanghai, China.
FAU - Yi, Xuemei
AU  - Yi X
AD  - Department of Dermatology, Shanghai Skin Disease Hospital, Shanghai, China.
FAU - Li, Ying
AU  - Li Y
AD  - Department of Dermatology, Shanghai Skin Disease Hospital, Shanghai, China.
FAU - Ding, Yangfeng
AU  - Ding Y
AD  - Department of Dermatology, Shanghai Skin Disease Hospital, Shanghai, China. 
      dingyangfeng_dr@163.com.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20180618
PL  - England
TA  - Lasers Med Sci
JT  - Lasers in medical science
JID - 8611515
SB  - IM
MH  - Adult
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Psoriasis/*radiotherapy
MH  - Quality of Life
MH  - Scalp/*pathology/*radiation effects
MH  - Treatment Outcome
MH  - *Ultraviolet Therapy/adverse effects
MH  - Young Adult
OTO - NOTNLM
OT  - Narrowband UVB
OT  - Psoriasis
OT  - Scalp
OT  - UVA1
EDAT- 2018/06/20 06:00
MHDA- 2019/04/16 06:00
CRDT- 2018/06/20 06:00
PHST- 2018/03/19 00:00 [received]
PHST- 2018/06/12 00:00 [accepted]
PHST- 2018/06/20 06:00 [pubmed]
PHST- 2019/04/16 06:00 [medline]
PHST- 2018/06/20 06:00 [entrez]
AID - 10.1007/s10103-018-2564-z [pii]
AID - 10.1007/s10103-018-2564-z [doi]
PST - ppublish
SO  - Lasers Med Sci. 2018 Dec;33(9):1979-1982. doi: 10.1007/s10103-018-2564-z. Epub 
      2018 Jun 18.