PMID- 29920389
OWN - NLM
STAT- MEDLINE
DCOM- 20181016
LR  - 20181016
IS  - 1878-8769 (Electronic)
IS  - 1878-8750 (Linking)
VI  - 117
DP  - 2018 Sep
TI  - Long-Term Minimum Clinically Important Difference in Health-Related Quality of 
      Life Scores After Instrumented Lumbar Interbody Fusion for Low-Grade Isthmic 
      Spondylolisthesis.
PG  - e493-e499
LID - S1878-8750(18)31278-6 [pii]
LID - 10.1016/j.wneu.2018.06.063 [doi]
AB  - BACKGROUND: Despite its growing popularity, no comparative studies have explored 
      the minimum clinically important difference (MCID) of health-related quality of 
      life scores following lumbar interbody fusion (LIF) performed on a single-level 
      adult low-grade isthmic spondylolisthesis (LGIS). OBJECTIVE: The purpose of this 
      study is to investigate factors related to MCID of health-related quality of life 
      scores following instrumented LIF performed on a single-level adult LGIS. 
      METHODS: Consecutive patients who underwent instrumented LIF for single-level 
      LGIS were reviewed. The inclusion criteria were adult patients who underwent L4-5 
      or L5-S1, underwent anterior lumbar interbody fusion or transforaminal lumbar 
      interbody fusion with a posterior screw fixation, and had a minimum 36-month 
      postoperative follow-up period. MCID was defined as having an improved score of 
      visual analog scale (VAS) back and leg pain >3 and Oswestry Disability Index 
      (ODI) >12. Patients were subdivided into groups named "achievement" (A) and 
      "nonachievement" (N) depending on their postoperative MCID for each 
      health-related quality of life score category. RESULTS: One-hundred and five 
      patients met the inclusion criteria. The overall achievement of MCID for VAS 
      back, leg, and ODI was 80%, 73.3%, and 82.9%. MCID-VAS leg and ODI were less 
      achieved at the L5-S1 level than at the L4-5 level. Postoperatively, disk height 
      was higher and segmental lordosis (SL) was lower in group A of MCID-VAS leg. SL 
      was lower in group A of MCID-ODI. CONCLUSIONS: We postulate that excessive SL 
      does not affect lumbar lordosis; rather, it can result in lowering posterior disk 
      height. The decrease in posterior DH may lead to a decreased foraminal height 
      that, in turn, can lead to nerve root compression. Proper restoration of disk 
      height and bone fusion is more important than restoration of more segmental 
      lordosis or slip reduction for isthmic spondylolisthesis.
CI  - Copyright (c) 2018 Elsevier Inc. All rights reserved.
FAU - Seuk, Ju-Wan
AU  - Seuk JW
AD  - Department of Neurosurgery, Chungdam Wooridul Spine Hospital, Seoul, Republic of 
      Korea.
FAU - Bae, Junseok
AU  - Bae J
AD  - Department of Neurosurgery, Chungdam Wooridul Spine Hospital, Seoul, Republic of 
      Korea. Electronic address: jsbaemd@gmail.com.
FAU - Shin, Sang-Ha
AU  - Shin SH
AD  - Department of Neurosurgery, Chungdam Wooridul Spine Hospital, Seoul, Republic of 
      Korea.
FAU - Lee, Sang-Ho
AU  - Lee SH
AD  - Department of Neurosurgery, Chungdam Wooridul Spine Hospital, Seoul, Republic of 
      Korea.
LA  - eng
PT  - Journal Article
DEP - 20180618
PL  - United States
TA  - World Neurosurg
JT  - World neurosurgery
JID - 101528275
SB  - IM
MH  - Bone Screws
MH  - Female
MH  - Humans
MH  - Intervertebral Disc Degeneration/complications/surgery
MH  - Lordosis/diagnostic imaging/psychology/surgery
MH  - Lumbar Vertebrae/diagnostic imaging/*surgery
MH  - Male
MH  - Middle Aged
MH  - Postoperative Complications/etiology
MH  - Pseudarthrosis/complications/surgery
MH  - Quality of Life/psychology
MH  - Radiography
MH  - Retrospective Studies
MH  - Spinal Fusion/*methods
MH  - Spondylolisthesis/diagnostic imaging/psychology/*surgery
OTO - NOTNLM
OT  - Disk height
OT  - Low-grade isthmic spondylolisthesis
OT  - Lumbar interbody fusion
OT  - MCID
OT  - Segmental lordosis
EDAT- 2018/06/20 06:00
MHDA- 2018/10/17 06:00
CRDT- 2018/06/20 06:00
PHST- 2017/09/20 00:00 [received]
PHST- 2018/06/08 00:00 [revised]
PHST- 2018/06/09 00:00 [accepted]
PHST- 2018/06/20 06:00 [pubmed]
PHST- 2018/10/17 06:00 [medline]
PHST- 2018/06/20 06:00 [entrez]
AID - S1878-8750(18)31278-6 [pii]
AID - 10.1016/j.wneu.2018.06.063 [doi]
PST - ppublish
SO  - World Neurosurg. 2018 Sep;117:e493-e499. doi: 10.1016/j.wneu.2018.06.063. Epub 
      2018 Jun 18.