PMID- 29931125
OWN - NLM
STAT- MEDLINE
DCOM- 20190201
LR  - 20190201
IS  - 1749-5024 (Electronic)
IS  - 1749-5016 (Print)
IS  - 1749-5016 (Linking)
VI  - 13
IP  - 7
DP  - 2018 Sep 4
TI  - Higher levels of trait emotional awareness are associated with more efficient 
      global information integration throughout the brain: a graph-theoretic analysis 
      of resting state functional connectivity.
PG  - 665-675
LID - 10.1093/scan/nsy047 [doi]
AB  - Previous studies have suggested that trait differences in emotional awareness 
      (tEA) are clinically relevant, and associated with differences in neural 
      structure/function. While multiple leading theories suggest that conscious 
      awareness requires widespread information integration across the brain, no study 
      has yet tested the hypothesis that higher tEA corresponds to more efficient 
      brain-wide information exchange. Twenty-six healthy volunteers (13 females) 
      underwent a resting state functional magnetic resonance imaging scan, and 
      completed the Levels of Emotional Awareness Scale (LEAS; a measure of tEA) and 
      the Wechsler Abbreviated Scale of Intelligence (WASI-II; a measure of general 
      intelligence quotient [IQ]). Using a whole-brain (functionally defined) region of 
      interest (ROI) atlas, we computed several graph theory metrics to assess the 
      efficiency of brain-wide information exchange. After statistically controlling 
      for differences in age, gender and IQ, we first observed a significant 
      relationship between higher LEAS scores and greater average degree (i.e. overall 
      whole-brain network density). When controlling for average degree, we found that 
      higher LEAS scores were also associated with shorter average path lengths across 
      the collective network of all included ROIs. These results jointly suggest that 
      individuals with higher tEA display more efficient global information exchange 
      throughout the brain. This is consistent with the idea that conscious awareness 
      requires global accessibility of represented information.
FAU - Smith, Ryan
AU  - Smith R
AD  - Department of Psychiatry, University of Arizona, Tucson, AZ, USA.
FAU - Sanova, Anna
AU  - Sanova A
AD  - Department of Psychiatry, University of Arizona, Tucson, AZ, USA.
FAU - Alkozei, Anna
AU  - Alkozei A
AD  - Department of Psychiatry, University of Arizona, Tucson, AZ, USA.
FAU - Lane, Richard D
AU  - Lane RD
AD  - Department of Psychiatry, University of Arizona, Tucson, AZ, USA.
FAU - Killgore, William D S
AU  - Killgore WDS
AD  - Department of Psychiatry, University of Arizona, Tucson, AZ, USA.
LA  - eng
PT  - Journal Article
PL  - England
TA  - Soc Cogn Affect Neurosci
JT  - Social cognitive and affective neuroscience
JID - 101288795
SB  - IM
MH  - Adult
MH  - Awareness/*physiology
MH  - Brain/*physiology
MH  - Brain Mapping
MH  - Emotions/*physiology
MH  - Female
MH  - Healthy Volunteers
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Mental Processes/*physiology
MH  - Neural Pathways/*physiology
MH  - Rest/physiology
MH  - Wechsler Scales
MH  - Young Adult
PMC - PMC6121141
EDAT- 2018/06/23 06:00
MHDA- 2019/02/02 06:00
PMCR- 2018/07/19
CRDT- 2018/06/23 06:00
PHST- 2018/01/18 00:00 [received]
PHST- 2018/06/18 00:00 [accepted]
PHST- 2018/06/23 06:00 [pubmed]
PHST- 2019/02/02 06:00 [medline]
PHST- 2018/06/23 06:00 [entrez]
PHST- 2018/07/19 00:00 [pmc-release]
AID - 5042249 [pii]
AID - nsy047 [pii]
AID - 10.1093/scan/nsy047 [doi]
PST - ppublish
SO  - Soc Cogn Affect Neurosci. 2018 Sep 4;13(7):665-675. doi: 10.1093/scan/nsy047.