PMID- 29935047 OWN - NLM STAT- MEDLINE DCOM- 20190412 LR - 20190412 IS - 1540-8159 (Electronic) IS - 0147-8389 (Linking) VI - 41 IP - 9 DP - 2018 Sep TI - Effect of radiofrequency on epicardial myocardium after ablation of ventricular arrhythmias from within coronary sinus. PG - 1060-1068 LID - 10.1111/pace.13429 [doi] AB - BACKGROUND: Radiofrequency (RF) ablation of idiopathic ventricular arrhythmias (IVA) from the coronary venous system (CVS) has been increasingly performed, but real effect of ablation lesions from CVS on epicardial myocardium has not been studied. OBJECTIVE: To compare effects of RF delivered inside the distal CVS during ablation of IVAs originating from left ventricular summit (LVS) with IVAs ablated from right ventricular outflow tract (RVOT) using cardiac magnetic resonance imaging (CMRI). METHODS: Twenty consecutive patients with IVAs who underwent acutely successful RF ablation at initial appropriate sites, i.e., distal CVS (Group 1, n = 10) or RVOT (Group 2; n = 10) were enrolled. Detailed contrast-enhanced CMRI of each patient was performed 3 months later. Presence and location of scars, distance of CVS to epicardial ventricular myocardium were measured and analyzed. RESULTS: Group 1 consisted of 10 and Group 2 consisted of 10 patients. Three months after the ablation, only three patients in Group 1 had detectable late gadolinium enhancement (LGE) on CMRI while nine out of 10 patients in Group 2 had evident LGE on CMRI (P: 0.02). The mean distance of distal CVS to epicardial anterobasal myocardium was measured to be 8.8 +/- 1.6 mm in Group 1. In three cases that had detectable scar on superior anterobasal LV epicardium, the mean distance was 7.4 +/- 1.1 mm. CONCLUSIONS: RF delivery inside the CVS is less likely to produce detectable LGE on CMRI compared to RVOT. This may partially explain less than ideal long-term results after ablation of LVS IVAs from within the great cardiac vein/anterior interventricular vein. CI - (c) 2018 Wiley Periodicals, Inc. FAU - Candemir, Basar AU - Candemir B AUID- ORCID: 0000-0003-2657-7601 AD - Cardiology Department, Ankara University, Ankara, Turkiye. FAU - Ozyurek, Elif AU - Ozyurek E AD - Magnetic Resonance Imaging Division, Department of Radiology, Ankara University, Ankara, Turkiye. FAU - Vurgun, Kutay AU - Vurgun K AD - Cardiology Department, Ankara University, Ankara, Turkiye. FAU - Turan, Nazli AU - Turan N AD - Cardiology Department, Ankara University, Ankara, Turkiye. FAU - Duzen, Veysel AU - Duzen V AD - Cardiology Department, Gaziantep Ersin Arslan Research Hospital, Ankara, Turkiye. FAU - Goksuluk, Huseyin AU - Goksuluk H AD - Cardiology Department, Ankara University, Ankara, Turkiye. FAU - Ozyuncu, Nil AU - Ozyuncu N AD - Cardiology Department, Ankara University, Ankara, Turkiye. FAU - Kurklu, Seda AU - Kurklu S AD - Cardiology Department, Ankara University, Ankara, Turkiye. FAU - Altin, Timucin AU - Altin T AD - Cardiology Department, Ankara University, Ankara, Turkiye. FAU - Akyurek, Omer AU - Akyurek O AD - Cardiology Department, Ankara University, Ankara, Turkiye. FAU - Erol, Cetin AU - Erol C AD - Cardiology Department, Ankara University, Ankara, Turkiye. LA - eng PT - Journal Article DEP - 20180719 PL - United States TA - Pacing Clin Electrophysiol JT - Pacing and clinical electrophysiology : PACE JID - 7803944 RN - 0 (Contrast Media) SB - IM CIN - Pacing Clin Electrophysiol. 2018 Sep;41(9):1069-1070. PMID: 29935024 MH - Adult MH - Computed Tomography Angiography MH - Contrast Media MH - Coronary Angiography MH - Coronary Sinus/diagnostic imaging/physiopathology/*surgery MH - Coronary Vessels/diagnostic imaging/physiopathology/surgery MH - Echocardiography MH - Electrocardiography MH - Electrophysiologic Techniques, Cardiac MH - Female MH - Humans MH - Magnetic Resonance Imaging/methods MH - Male MH - Middle Aged MH - Pericardium/diagnostic imaging/physiopathology/surgery MH - Radiofrequency Ablation/*methods MH - Tachycardia, Ventricular/diagnostic imaging/physiopathology/*surgery MH - Treatment Outcome MH - Ventricular Outflow Obstruction/diagnostic imaging/physiopathology/surgery OTO - NOTNLM OT - cardiac magnetic resonance imaging OT - coronary sinus OT - idiopathic ventricular arrhythmias OT - left ventricular summit OT - radiofrequency ablation EDAT- 2018/06/24 06:00 MHDA- 2019/04/13 06:00 CRDT- 2018/06/24 06:00 PHST- 2018/01/16 00:00 [received] PHST- 2018/03/16 00:00 [revised] PHST- 2018/03/27 00:00 [accepted] PHST- 2018/06/24 06:00 [pubmed] PHST- 2019/04/13 06:00 [medline] PHST- 2018/06/24 06:00 [entrez] AID - 10.1111/pace.13429 [doi] PST - ppublish SO - Pacing Clin Electrophysiol. 2018 Sep;41(9):1060-1068. doi: 10.1111/pace.13429. Epub 2018 Jul 19.