PMID- 29938158 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230926 IS - 2191-1363 (Print) IS - 2191-1363 (Electronic) IS - 2191-1363 (Linking) VI - 7 IP - 6 DP - 2018 Jun TI - A Multiple Stimuli-Sensitive Low-Molecular-Weight Gel with an Aggregate-Induced Emission Effect for Sol-Gel Transition Detection. PG - 457-462 LID - 10.1002/open.201800063 [doi] AB - A low-molecular-weight gel (LMWG) with a hydrazone moiety and an aggregate-induced emission (AIE) unit was fabricated; the self-assembly and disassembly of the LMWG under different stimuli conditions were studied. The LMWG exhibited multiple stimuli sensitivity with temperature, light, ions, and ionic strength. The hydrazone was integrated into the gelator to act as ion sensing sites and hydrogen bond donor groups to fulfil the task of ion recognition of Ni(2+), BH(4)(-), and OH(-), as well as ion-controlled reversible sol-gel recovery by adding H(+) for deprotonation; it also broke under UV irradiation to evoke light-sensitivity. In addition, the sol-gel transition of the gel was detected by the AIE effect. The research provided an effective strategy in fabricating multiple stimuli-sensitive LMWGs for potential biomedical applications. FAU - Wang, Hao AU - Wang H AD - College of Chemistry and Materials Engineering Wenzhou University, Chashan Town 325000 Wenzhou City Zhejiang Province P. R. China. FAU - Liu, Qihong AU - Liu Q AD - College of Chemistry and Materials Engineering Wenzhou University, Chashan Town 325000 Wenzhou City Zhejiang Province P. R. China. FAU - Hu, Yalong AU - Hu Y AD - College of Chemistry and Materials Engineering Wenzhou University, Chashan Town 325000 Wenzhou City Zhejiang Province P. R. China. FAU - Liu, Miaochang AU - Liu M AD - College of Chemistry and Materials Engineering Wenzhou University, Chashan Town 325000 Wenzhou City Zhejiang Province P. R. China. FAU - Huang, Xiaobo AU - Huang X AD - College of Chemistry and Materials Engineering Wenzhou University, Chashan Town 325000 Wenzhou City Zhejiang Province P. R. China. FAU - Gao, Wenxia AU - Gao W AUID- ORCID: 0000-0002-3373-9827 AD - College of Chemistry and Materials Engineering Wenzhou University, Chashan Town 325000 Wenzhou City Zhejiang Province P. R. China. FAU - Wu, Huayue AU - Wu H AD - College of Chemistry and Materials Engineering Wenzhou University, Chashan Town 325000 Wenzhou City Zhejiang Province P. R. China. LA - eng PT - Journal Article DEP - 20180619 PL - Germany TA - ChemistryOpen JT - ChemistryOpen JID - 101594811 PMC - PMC6010791 OTO - NOTNLM OT - aggregate-induced emission effect OT - biomedical applications OT - low-molecular-weight gels OT - multiple stimuli sensitivity OT - sensing EDAT- 2018/06/26 06:00 MHDA- 2018/06/26 06:01 PMCR- 2018/06/01 CRDT- 2018/06/26 06:00 PHST- 2018/04/18 00:00 [received] PHST- 2018/06/26 06:00 [entrez] PHST- 2018/06/26 06:00 [pubmed] PHST- 2018/06/26 06:01 [medline] PHST- 2018/06/01 00:00 [pmc-release] AID - OPEN201800063 [pii] AID - 10.1002/open.201800063 [doi] PST - epublish SO - ChemistryOpen. 2018 Jun 19;7(6):457-462. doi: 10.1002/open.201800063. eCollection 2018 Jun.