PMID- 29941728
OWN - NLM
STAT- MEDLINE
DCOM- 20180716
LR  - 20181114
IS  - 1998-3689 (Electronic)
IS  - 0301-4738 (Print)
IS  - 0301-4738 (Linking)
VI  - 66
IP  - 7
DP  - 2018 Jul
TI  - Polypoidal choroidal vasculopathy: Pearls in diagnosis and management.
PG  - 896-908
LID - 10.4103/ijo.IJO_1136_17 [doi]
AB  - Polypoidal choroidal vasculopathy (PCV) is increasingly recognized as an 
      important cause of exudative maculopathy in Asians as against Wet age-related 
      macular degeneration in Caucasians. A panel of retinal experts methodically 
      evaluated pertinent updated literature on PCV with thorough PubMed/MEDLINE 
      search. Based on this, the panel agreed upon and proposed the current consensus 
      recommendations in the diagnosis (clinical and imaging), management and follow-up 
      schedule of PCV. Diagnosis of PCV should be based on the gold standard 
      indocyanine green angiography which demonstrates early nodular hyperfluorescence 
      signifying the polyp with additional features such as abnormal vascular network 
      (AVN). Optical coherence tomography is an excellent adjuvant for diagnosing PCV, 
      monitoring disease activity, and decision-making regarding the treatment. Current 
      treatment modalities for PCV include photodynamic therapy, anti-vascular 
      endothelial growth factor agents, and thermal laser. Choice of specific treatment 
      modality and prognosis depends on multiple factors such as the location and size 
      of PCV lesion, presence or absence of polyp with residual AVN, amount of 
      submacular hemorrhage, presence or absence of leakage on fundus fluorescein 
      angiography, visual acuity, and so on. Current recommendations would be 
      invaluable for the treating physician in diagnosing PCV and in formulating the 
      best possible individualized treatment strategy for optimal outcomes in PCV 
      management.
FAU - Anantharaman, Giridhar
AU  - Anantharaman G
AD  - Department of Vitreoretina, Giridhar Eye Institute, Kochi, Kerala, India.
FAU - Sheth, Jay
AU  - Sheth J
AD  - Department of Vitreoretina, Giridhar Eye Institute, Kochi, Kerala, India.
FAU - Bhende, Muna
AU  - Bhende M
AD  - Department of Vitreoretinal Services, Sri Bhagwan Mahavir Vitreoretinal Services, 
      Medical Research Foundation, Chennai, Tamil Nadu, India.
FAU - Narayanan, Raja
AU  - Narayanan R
AD  - Smt. Kanuri Santhamma Centre for Vitreo Retinal Diseases, LV Prasad Eye 
      Institute, Hyderabad, Telangana, India.
FAU - Natarajan, Sundaram
AU  - Natarajan S
AD  - Department of Vitreoretina, Aditya Jyot Eye Hospital Pvt. Ltd., Mumbai, 
      Maharashtra, India.
FAU - Rajendran, Anand
AU  - Rajendran A
AD  - Retina-Vitreous Service, Aravind Eye Hospital, Postgraduate Institute of 
      Ophthalmology, Madurai, Tamil Nadu, India.
FAU - Manayath, George
AU  - Manayath G
AD  - Department of Retina and Ocular Oncology, Aravind Eye Hospital, Coimbatore, Tamil 
      Nadu, India.
FAU - Sen, Parveen
AU  - Sen P
AD  - Department of Vitreoretinal Services, Sri Bhagwan Mahavir Vitreoretinal Services, 
      Medical Research Foundation, Chennai, Tamil Nadu, India.
FAU - Biswas, Rupak
AU  - Biswas R
AD  - Department of Vitreoretina, B. B. Eye Foundation, Kolkata, West Bengal, India.
FAU - Banker, Alay
AU  - Banker A
AD  - Bankers Retina Clinic and Laser Centre, Ahmedabad, Gujarat, India.
FAU - Gupta, Charu
AU  - Gupta C
AD  - Shroff Eye Center, New Delhi, India.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - India
TA  - Indian J Ophthalmol
JT  - Indian journal of ophthalmology
JID - 0405376
SB  - IM
MH  - Choroid/*blood supply
MH  - Choroid Diseases/*diagnosis/*therapy
MH  - *Disease Management
MH  - Humans
MH  - Polyps/*diagnosis/*therapy
PMC - PMC6032720
OTO - NOTNLM
OT  - Abnormal vascular network
OT  - indocyanine green angiography
OT  - optical coherence tomography
OT  - photodynamic therapy
OT  - polypoidal choroidal vasculopathy
OT  - thermal laser
COIS- There are no conflicts of interest
EDAT- 2018/06/27 06:00
MHDA- 2018/07/17 06:00
PMCR- 2018/07/01
CRDT- 2018/06/27 06:00
PHST- 2018/06/27 06:00 [entrez]
PHST- 2018/06/27 06:00 [pubmed]
PHST- 2018/07/17 06:00 [medline]
PHST- 2018/07/01 00:00 [pmc-release]
AID - IndianJOphthalmol_2018_66_7_896_234954 [pii]
AID - IJO-66-896 [pii]
AID - 10.4103/ijo.IJO_1136_17 [doi]
PST - ppublish
SO  - Indian J Ophthalmol. 2018 Jul;66(7):896-908. doi: 10.4103/ijo.IJO_1136_17.