PMID- 29941755
OWN - NLM
STAT- MEDLINE
DCOM- 20180717
LR  - 20181114
IS  - 1998-3689 (Electronic)
IS  - 0301-4738 (Print)
IS  - 0301-4738 (Linking)
VI  - 66
IP  - 7
DP  - 2018 Jul
TI  - A case of human leukocyte antigen B-27-associated ocular hypotony successfully 
      treated with golimumab.
PG  - 1006-1008
LID - 10.4103/ijo.IJO_120_18 [doi]
AB  - A 42-year-old male presented to us after an episode of acute anterior human 
      leukocyte antigen (HLA)-B27-associated uveitis, and intraocular pressure (IOP) in 
      the right eye was 4 mmHg. Ultrasound biomicroscopy revealed ciliary body edema 
      with supraciliary effusion. He was on a frequent topical corticosteroid, and oral 
      steroid in addition to receiving a periocular injection depot corticosteroid 20 
      days back. He was started on treatment with subcutaneous golimumab (GLM). After a 
      month, his IOP in the right eye was 14 mm of Hg with UBM showing resolution of 
      ciliary body edema. GLM can be useful in the management of steroid-resistant 
      cases of HLA B-27-associated ocular hypotony.
FAU - Majumder, Parthopratim Dutta
AU  - Majumder PD
AD  - Department of Uvea and Intraocular Inflammation, Sankara Nethralaya, Chennai, 
      Tamil Nadu, India.
FAU - Lakra, Ruchika
AU  - Lakra R
AD  - Department of Uvea and Intraocular Inflammation, Sankara Nethralaya, Chennai, 
      Tamil Nadu, India.
FAU - Yamuna, G
AU  - Yamuna G
AD  - Department of Glaucoma, Sankara Nethralaya, Chennai, Tamil Nadu, India.
FAU - Majumder, Anindya Kishore
AU  - Majumder AK
AD  - Departement of Uvea, Sankara Nethralaya, Kolkata, India.
FAU - Kaushik, Viswanath
AU  - Kaushik V
AD  - Department of Rheumatology, Apollo Hospital, Chennai, Tamil Nadu, India.
LA  - eng
PT  - Case Reports
PL  - India
TA  - Indian J Ophthalmol
JT  - Indian journal of ophthalmology
JID - 0405376
RN  - 0 (Antibodies, Monoclonal)
RN  - 0 (HLA-B27 Antigen)
RN  - 91X1KLU43E (golimumab)
SB  - IM
MH  - Adult
MH  - Antibodies, Monoclonal/*administration & dosage
MH  - Ciliary Body/*diagnostic imaging
MH  - HLA-B27 Antigen/*immunology
MH  - Humans
MH  - Injections, Subcutaneous
MH  - Intraocular Pressure/*physiology
MH  - Male
MH  - Microscopy, Acoustic
MH  - Ocular Hypotension/drug therapy/*immunology/physiopathology
MH  - Tonometry, Ocular
PMC - PMC6032752
OTO - NOTNLM
OT  - Golimumab
OT  - human leukocyte antigen B-27
OT  - ocular hypotony
OT  - ultrasound biomicroscopy
COIS- There are no conflicts of interest
EDAT- 2018/06/27 06:00
MHDA- 2018/07/18 06:00
PMCR- 2018/07/01
CRDT- 2018/06/27 06:00
PHST- 2018/06/27 06:00 [entrez]
PHST- 2018/06/27 06:00 [pubmed]
PHST- 2018/07/18 06:00 [medline]
PHST- 2018/07/01 00:00 [pmc-release]
AID - IndianJOphthalmol_2018_66_7_1006_234957 [pii]
AID - IJO-66-1006 [pii]
AID - 10.4103/ijo.IJO_120_18 [doi]
PST - ppublish
SO  - Indian J Ophthalmol. 2018 Jul;66(7):1006-1008. doi: 10.4103/ijo.IJO_120_18.