PMID- 29945809
OWN - NLM
STAT- MEDLINE
DCOM- 20190128
LR  - 20190128
IS  - 1776-2588 (Electronic)
IS  - 0761-8425 (Linking)
VI  - 35
IP  - 7
DP  - 2018 Sep
TI  - [Osteochondroplastic tracheobronchopathy: About three cases].
PG  - 738-744
LID - S0761-8425(18)30193-1 [pii]
LID - 10.1016/j.rmr.2017.10.668 [doi]
AB  - INTRODUCTION: Osteochondroplastic tracheobronchopathy (OCTB) is a rare disorder 
      of unknown cause that affects the tracheobronchial tree. It is characterized by 
      multiple cartilaginous formations or bone nodules projecting into the tracheal or 
      proximal bronchial lumen. It is usually asymptomatic because of the slow 
      progression of the nodules. However, chronic cough, recurrent hemoptysis or 
      recurrent respiratory infections have been reported. OBSERVATIONS: We describe 
      the cases of three patients with symptomatic OCTB: two men and one woman 
      consulting for bronchial infections or pneumonia with sputum difficulties (2 
      cases) or simply for chronic cough (1 case). In all three cases, the diagnosis 
      was suspected because of irregularities of the tracheal or bronchial wall with 
      calcification seen on imaging and confirmed at bronchoscopy with biopsy 
      specimens. No specific therapy was initiated in these patients except for the 
      treatment of associated complications or comorbidities. CONCLUSION: OCTB is a 
      benign pathology which can lead to bronchial symptoms ranging from mild cough to 
      severe airway obstruction due to tracheobronchial stenosis. A key to diagnosis, 
      limiting non-essential examinations and biopsies, is to consider OCTB based on CT 
      scan or bronchoscopy based on irregularities of the tracheal or bronchial wall 
      with calcification.
CI  - Copyright (c) 2018 SPLF. Published by Elsevier Masson SAS. All rights reserved.
FAU - Ferreira, M
AU  - Ferreira M
AD  - Service de pneumologie et d'explorations fonctionnels respiratoires, centre 
      hospitalier universitaire de Tours, 37000 Tours, France. Electronic address: 
      marion-ferreira@hotmail.fr.
FAU - Morel, H
AU  - Morel H
AD  - Service de pneumologie et d'oncologie thoracique, centre hospitalier Regional 
      d'Orleans, 45067 Orleans, France.
FAU - Dixmier, A
AU  - Dixmier A
AD  - Service de pneumologie et d'oncologie thoracique, centre hospitalier Regional 
      d'Orleans, 45067 Orleans, France.
FAU - Arbion, F
AU  - Arbion F
AD  - Service d'anatomie et cytologie pathologiques, centre hospitalier universitaire 
      de Tours, 37000 Tours, France.
FAU - Marchand-Adam, S
AU  - Marchand-Adam S
AD  - Service de pneumologie et d'explorations fonctionnels respiratoires, centre 
      hospitalier universitaire de Tours, 37000 Tours, France; Inserm U1100, faculte de 
      medecine de Tours, universite Francois Rabelais, 37000 Tours, France.
LA  - fre
PT  - Case Reports
PT  - Journal Article
TT  - Tracheobronchopathie osteochondroplastique : a propos de 3 cas.
DEP - 20180623
PL  - France
TA  - Rev Mal Respir
JT  - Revue des maladies respiratoires
JID - 8408032
SB  - IM
MH  - Aged
MH  - Airway Obstruction/diagnosis/etiology/pathology
MH  - Bronchial Diseases/*diagnosis/pathology
MH  - Bronchoscopy
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Osteochondrodysplasias/*diagnosis/pathology
MH  - Tracheal Diseases/*diagnosis/pathology
OTO - NOTNLM
OT  - Calcification
OT  - Cough
OT  - Dyspnea
OT  - Dyspnee
OT  - Infection
OT  - Toux
OT  - Tracheal diseases
OT  - Trachee
EDAT- 2018/06/28 06:00
MHDA- 2019/01/29 06:00
CRDT- 2018/06/28 06:00
PHST- 2017/05/27 00:00 [received]
PHST- 2017/10/25 00:00 [accepted]
PHST- 2018/06/28 06:00 [pubmed]
PHST- 2019/01/29 06:00 [medline]
PHST- 2018/06/28 06:00 [entrez]
AID - S0761-8425(18)30193-1 [pii]
AID - 10.1016/j.rmr.2017.10.668 [doi]
PST - ppublish
SO  - Rev Mal Respir. 2018 Sep;35(7):738-744. doi: 10.1016/j.rmr.2017.10.668. Epub 2018 
      Jun 23.