PMID- 29949834 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200929 IS - 2092-7355 (Print) IS - 2092-7363 (Electronic) IS - 2092-7355 (Linking) VI - 10 IP - 4 DP - 2018 Jul TI - Factors Affecting Food Allergy-Related Quality of Life From Parents' Perception in Turkish Children. PG - 379-386 LID - 10.4168/aair.2018.10.4.379 [doi] AB - PURPOSE: Food allergy (FA) affects the daily lives of children and parents in varying degrees. The Food Allergy Quality of Life Questionnaire-Parent Form (FAQLQ-PF) is a valid and reliable instrument to assess the quality of life (QoL) of children from parents' perception. The aim of this study was to validate and determine the reliability of the Turkish FAQLQ-PF and to assess QoL in food-allergic children. METHODS: Children aged between 0 and 12 years and diagnosed with immunoglobulin E (IgE)-mediated FA for at least 1 month were enrolled. The English FAQLQ-PF was translated into Turkish according to the World Health Organization guidelines. The Food Allergy Independent Measure and the Turkish Child Health Questionnaire-Parent Form 50 were used for construct validity. RESULTS: One hundred and fifty-seven patients participated. The median age of patients and FA duration were 2.4 years (1.2-5.2 years, interquartile-ranges) and 2 years (0.8-5.1), respectively. Ninety-six (61.1%) patients had anaphylaxis. The Cronbach's alpha coefficient and intra-class correlation coefficient for test-retest reliability was good for all age groups of children (<4, 4-6, and 7-12 years). Patients with either asthma or anaphylaxis had worse scores than others. Total scores of FAQLQ-PF tended to increase with age. Patients aged 7-12 had the highest total scores among all patients (2.2+/-0.1, 3.0+/-0.2, and 3.3+/-0.3 for <4, 4-6, and 7-12 years, respectively, P<0.001, P for trend <0.001). Other factors causing the poor QoL were cow's milk allergy, sibling allergy, mother's age over 30 years, mother's high education level and lower number of persons in household. CONCLUSIONS: The Turkish FAQLQ-PF is a valid and reliable scale. FA-related QoL was significantly worse with age. Coexistent asthma, anaphylaxis regardless of its severity, cow's milk allergy, sibling allergy and the older and educated mothers seem to poorly affect QoL. CI - Copyright (c) 2018 The Korean Academy of Asthma, Allergy and Clinical Immunology . The Korean Academy of Pediatric Allergy and Respiratory Disease. FAU - Arik Yilmaz, Ebru AU - Arik Yilmaz E AUID- ORCID: 0000-0002-6204-2754 AD - Department of Pediatric Allergy, Hacettepe University School of Medicine, Ankara, Turkey. FAU - Cavkaytar, Ozlem AU - Cavkaytar O AUID- ORCID: 0000-0002-5747-7032 AD - Department of Pediatric Allergy, Hacettepe University School of Medicine, Ankara, Turkey. FAU - Buyuktiryaki, Betul AU - Buyuktiryaki B AD - Department of Pediatric Allergy, Hacettepe University School of Medicine, Ankara, Turkey. FAU - Soyer, Ozge AU - Soyer O AD - Department of Pediatric Allergy, Hacettepe University School of Medicine, Ankara, Turkey. FAU - Sahiner, Umit M AU - Sahiner UM AD - Department of Pediatric Allergy, Hacettepe University School of Medicine, Ankara, Turkey. FAU - Sekerel, Bulent E AU - Sekerel BE AUID- ORCID: 0000-0003-4232-3396 AD - Department of Pediatric Allergy, Hacettepe University School of Medicine, Ankara, Turkey. FAU - DunnGalvin, Audrey AU - DunnGalvin A AUID- ORCID: 0000-0002-1540-3959 AD - Department of Paediatrics and Child Health, Cork University Hospital, Wilton, Cork, Ireland. FAU - Karabulut, Erdem AU - Karabulut E AUID- ORCID: 0000-0002-7811-8215 AD - Department of Statistics, Hacettepe University School of Medicine, Ankara, Turkey. FAU - Sackesen, Cansin AU - Sackesen C AUID- ORCID: 0000-0002-1115-9805 AD - Department of Pediatric Allergy, Hacettepe University School of Medicine, Ankara, Turkey. AD - Department of Pediatric Allergy, Koc University School of Medicine, Istanbul, Turkey. csackesen@ku.edu.tr. LA - eng PT - Journal Article PL - Korea (South) TA - Allergy Asthma Immunol Res JT - Allergy, asthma & immunology research JID - 101518382 PMC - PMC6021590 OTO - NOTNLM OT - Age OT - children OT - food allergy OT - quality of life OT - validation COIS- There are no financial or other issues that might lead to conflict of interest. EDAT- 2018/06/28 06:00 MHDA- 2018/06/28 06:01 PMCR- 2018/07/01 CRDT- 2018/06/28 06:00 PHST- 2017/11/10 00:00 [received] PHST- 2018/04/16 00:00 [revised] PHST- 2018/04/18 00:00 [accepted] PHST- 2018/07/01 00:00 [pmc-release] PHST- 2018/06/28 06:00 [entrez] PHST- 2018/06/28 06:00 [pubmed] PHST- 2018/06/28 06:01 [medline] AID - 10.379 [pii] AID - 10.4168/aair.2018.10.4.379 [doi] PST - ppublish SO - Allergy Asthma Immunol Res. 2018 Jul;10(4):379-386. doi: 10.4168/aair.2018.10.4.379.