PMID- 29951563 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200929 IS - 2326-3253 (Print) IS - 2326-3253 (Electronic) IS - 2326-3253 (Linking) VI - 5 DP - 2018 TI - Infliximab-Induced Aseptic Meningitis in a Patient with Crohn's Disease. PG - e48 LID - 10.14309/crj.2018.48 [doi] LID - e48 AB - Infliximab is an anti-tumor necrosis factor alpha (TNFalpha) monoclonal antibody that treats moderate-to-severe Crohn's disease. In rare cases, infliximab has been associated with drug-induced aseptic meningitis. We present a 46-year-old woman with migraines and inflammatory Crohn's colitis treated with intravenous infliximab and methotrexate. She developed nuchal rigidity, photophobia, and headache 2 days after each of her infliximab infusions, with symptom resolution 1 week post-infusion. Her exam, imaging, and cerebrospinal fluid analysis were consistent with drug-induced aseptic meningitis. She discontinued infliximab and started vedolizumab with continued remission of her Crohn's disease. FAU - Junga, Zachary AU - Junga Z AD - Gastroenterology Service, Department of Medicine, Walter Reed National Military Medical Center, Bethesda, MD. FAU - Theeler, Brett AU - Theeler B AD - Neurology Service, Department of Medicine, Walter Reed National Military Medical Center, Bethesda, MD. FAU - Singla, Manish AU - Singla M AD - Gastroenterology Service, Department of Medicine, Walter Reed National Military Medical Center, Bethesda, MD. LA - eng PT - Case Reports DEP - 20180620 PL - United States TA - ACG Case Rep J JT - ACG case reports journal JID - 101638398 PMC - PMC6013687 EDAT- 2018/06/29 06:00 MHDA- 2018/06/29 06:01 PMCR- 2018/06/20 CRDT- 2018/06/29 06:00 PHST- 2018/03/01 00:00 [received] PHST- 2018/05/02 00:00 [accepted] PHST- 2018/06/29 06:00 [entrez] PHST- 2018/06/29 06:00 [pubmed] PHST- 2018/06/29 06:01 [medline] PHST- 2018/06/20 00:00 [pmc-release] AID - crj.2018.48 [pii] AID - 10.14309/crj.2018.48 [doi] PST - epublish SO - ACG Case Rep J. 2018 Jun 20;5:e48. doi: 10.14309/crj.2018.48. eCollection 2018.