PMID- 29959451
OWN - NLM
STAT- MEDLINE
DCOM- 20190103
LR  - 20190103
IS  - 1433-9285 (Electronic)
IS  - 0933-7954 (Linking)
VI  - 53
IP  - 11
DP  - 2018 Nov
TI  - Which mental disorders are associated with the greatest impairment in 
      functioning?
PG  - 1265-1276
LID - 10.1007/s00127-018-1554-6 [doi]
AB  - OBJECTIVE: The objective of this study is to estimate the comparative 
      associations of mental disorders with three measures of functional impairment: 
      the Global Assessment of Functioning (GAF); the number of days in the past 
      12 months of total inability to work or carry out normal activities because of 
      emotions, nerves, or mental health (i.e., days out of role); and a modified 
      version of the World Health Organization Disability Assessment Schedule 2.0 
      (WHODAS 2.0). METHODS: Secondary data analysis of the linked Mental Health 
      Surveillance Study and the National Survey on Drug Use and Health (n = 5653), 
      nationally representative population surveys conducted in the United States. 
      Generalized linear models assessed the independent effects of mental disorders on 
      each measure of functional impairment, controlling for mental disorder 
      comorbidity, physical health disorders, and sociodemographic factors. RESULTS: 
      The results varied across measures of functional impairment. However, mood 
      disorders generally tended to be associated with the greatest functional 
      impairment, anxiety disorders with intermediate impairment, and substance use 
      disorders with the least impairment. All 15 disorders were significantly 
      associated with the GAF score in multiple regression models, eight disorders were 
      significantly associated with the WHODAS score, and three disorders were 
      significantly associated with days out of role. CONCLUSIONS: Our results 
      highlight the value of complementary measures of functional impairment.
FAU - Edlund, Mark J
AU  - Edlund MJ
AD  - Behavioral and Urban Health, RTI International, 3040 E. Cornwallis Road, P.O. Box 
      12194, Research Triangle Park, NC, 27709-2194, USA. medlund@rti.org.
FAU - Wang, Jiantong
AU  - Wang J
AD  - Social Statistics, RTI International, University Center, Suite 119, 2951 Flowers 
      Road South, Atlanta, GA, 30341-5533, USA.
FAU - Brown, Kristen Gulledge
AU  - Brown KG
AD  - Behavioral Statistics, RTI International, 3040 E. Cornwallis Road, P.O. Box 
      12194, Research Triangle Park, NC, 27709-2194, USA.
FAU - Forman-Hoffman, Valerie L
AU  - Forman-Hoffman VL
AD  - Behavioral and Urban Health, RTI International, 3040 E. Cornwallis Road, P.O. Box 
      12194, Research Triangle Park, NC, 27709-2194, USA.
FAU - Calvin, Sara L
AU  - Calvin SL
AD  - Behavioral Health Surveillance and Analysis, RTI International, 3040 E. 
      Cornwallis Road, P.O. Box 12194, Research Triangle Park, NC, 27709-2194, USA.
FAU - Hedden, Sarra L
AU  - Hedden SL
AD  - Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental 
      Health Services Administration, 5600 Fishers Lane, Rockville, MD, 20857, USA.
FAU - Bose, Jonaki
AU  - Bose J
AD  - Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental 
      Health Services Administration, 5600 Fishers Lane, Rockville, MD, 20857, USA.
LA  - eng
GR  - HHSS283201000003C/Substance Abuse and Mental Health Services Administration/
PT  - Journal Article
DEP - 20180629
PL  - Germany
TA  - Soc Psychiatry Psychiatr Epidemiol
JT  - Social psychiatry and psychiatric epidemiology
JID - 8804358
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Disability Evaluation
MH  - Female
MH  - Health Surveys
MH  - Humans
MH  - Male
MH  - *Mental Disorders/complications/epidemiology
MH  - Middle Aged
MH  - *Severity of Illness Index
MH  - United States/epidemiology
MH  - Young Adult
OTO - NOTNLM
OT  - Disability
OT  - Functional impairment
OT  - Global Assessment of Functioning
OT  - Mental disorders
EDAT- 2018/07/01 06:00
MHDA- 2019/01/04 06:00
CRDT- 2018/07/01 06:00
PHST- 2017/06/13 00:00 [received]
PHST- 2018/06/14 00:00 [accepted]
PHST- 2018/07/01 06:00 [pubmed]
PHST- 2019/01/04 06:00 [medline]
PHST- 2018/07/01 06:00 [entrez]
AID - 10.1007/s00127-018-1554-6 [pii]
AID - 10.1007/s00127-018-1554-6 [doi]
PST - ppublish
SO  - Soc Psychiatry Psychiatr Epidemiol. 2018 Nov;53(11):1265-1276. doi: 
      10.1007/s00127-018-1554-6. Epub 2018 Jun 29.