PMID- 29964321 OWN - NLM STAT- MEDLINE DCOM- 20190118 LR - 20190118 IS - 1865-1682 (Electronic) IS - 1865-1674 (Linking) VI - 65 IP - 6 DP - 2018 Dec TI - Collared peccary (Pecari tajacu) are susceptible to porcine reproductive and respiratory syndrome virus (PRRSV). PG - 1712-1719 LID - 10.1111/tbed.12944 [doi] AB - Collared peccary (Pecari tajacu) and pigs (Sus scrofa) are two members of superfamily Suoidea that coexist in the Americas and share some of the same viral infections. Although porcine reproductive and respiratory syndrome virus (PRRSV) is among the most impactful pathogens of swine on a worldwide basis, the susceptibility of peccaries to PRRSV has not been investigated. In this study, three peccaries were intramuscularly inoculated with a PRRSV-2 field virus. One PRRSV-inoculated pig served as a positive control and two pigs and one peccary as negative controls. Serum samples were collected at regular intervals over a 23-day observation period and tested by PRRSV rtRT-PCR and isotype-specific (IgM, IgA, IgG) PRRSV ELISAs. The detection of viremia (DPI 3-23) and a PRRSV-specific humoural immune response (>/=DPI 10) supported the conclusion that collared peccary are susceptible to PRRSV. The results raise questions regarding the natural history of PRRSV in non-Sus members of superfamily Suoidea and, more broadly, their role in the evolution and ecology of PRRSV. CI - (c) 2018 Blackwell Verlag GmbH. FAU - Molina-Barrios, Ramon AU - Molina-Barrios R AD - Departamento de Ciencias Agronomicas y Veterinarias, Instituto Tecnologico de Sonora (ITSON), Cd. Obregon, Sonora, Mexico. FAU - Luevano-Adame, Jose AU - Luevano-Adame J AUID- ORCID: 0000-0003-1639-9717 AD - Departamento de Ciencias Agronomicas y Veterinarias, Instituto Tecnologico de Sonora (ITSON), Cd. Obregon, Sonora, Mexico. FAU - Henao-Diaz, Yuly Alexandra AU - Henao-Diaz YA AUID- ORCID: 0000-0002-1821-7641 AD - Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA. FAU - Gimenez-Lirola, Luis AU - Gimenez-Lirola L AUID- ORCID: 0000-0002-4407-7996 AD - Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA. FAU - Pineyro, Pablo AU - Pineyro P AD - Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA. FAU - Magtoto, Ronaldo AU - Magtoto R AD - Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA. FAU - Cedillo-Cobian, Jesus AU - Cedillo-Cobian J AD - Departamento de Ciencias Agronomicas y Veterinarias, Instituto Tecnologico de Sonora (ITSON), Cd. Obregon, Sonora, Mexico. FAU - Diaz-Rayo, Concepcion AU - Diaz-Rayo C AD - Departamento de Ciencias Agronomicas y Veterinarias, Instituto Tecnologico de Sonora (ITSON), Cd. Obregon, Sonora, Mexico. FAU - Hernandez, Jesus AU - Hernandez J AD - Laboratorio de Inmunologia, Centro de Investigacion en Alimentacion y Desarrollo A.C (CIAD), Hermosillo, Sonora, Mexico. FAU - Zimmerman, Jeffrey AU - Zimmerman J AUID- ORCID: 0000-0002-8107-2422 AD - Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, USA. LA - eng GR - Diagnostico Integral en Patologia Animal SC (DIPA, ITSON, Mexico)/ GR - Grupo SOLES (Mexico)/ GR - Secretaria de Educacion Publica/ GR - Programa de Fortalecimiento de la Calidad Educativa (PFCE 2018, Mexico)/ GR - Iowa State University Veterinary Diagnostic Laboratory/ PT - Journal Article DEP - 20180702 PL - Germany TA - Transbound Emerg Dis JT - Transboundary and emerging diseases JID - 101319538 RN - 0 (Antibodies, Viral) SB - IM MH - Animals MH - Antibodies, Viral/blood MH - Artiodactyla/*virology MH - Disease Susceptibility MH - Enzyme-Linked Immunosorbent Assay/veterinary MH - Female MH - Immunity, Humoral MH - Porcine Reproductive and Respiratory Syndrome/*virology MH - Porcine respiratory and reproductive syndrome virus/immunology/*isolation & purification MH - Swine MH - Viremia/*veterinary/virology OTO - NOTNLM OT - PRRSV OT - host OT - peccary OT - pigs OT - susceptibility EDAT- 2018/07/03 06:00 MHDA- 2019/01/19 06:00 CRDT- 2018/07/03 06:00 PHST- 2018/03/27 00:00 [received] PHST- 2018/05/16 00:00 [revised] PHST- 2018/06/05 00:00 [accepted] PHST- 2018/07/03 06:00 [pubmed] PHST- 2019/01/19 06:00 [medline] PHST- 2018/07/03 06:00 [entrez] AID - 10.1111/tbed.12944 [doi] PST - ppublish SO - Transbound Emerg Dis. 2018 Dec;65(6):1712-1719. doi: 10.1111/tbed.12944. Epub 2018 Jul 2.