PMID- 2996982
OWN - NLM
STAT- MEDLINE
DCOM- 19851218
LR  - 20210915
IS  - 0016-6731 (Print)
IS  - 0016-6731 (Linking)
VI  - 111
IP  - 3
DP  - 1985 Nov
TI  - Cellular genes in the mouse regulate in trans the expression of endogenous mouse 
      mammary tumor viruses.
PG  - 597-615
AB  - The transcriptional activities of the eleven mouse mammary tumor virus (MMTV) 
      proviruses endogenous to two sets of recombinant inbred (RI) mouse strains, BXD 
      and BXH, were characterized. Comparison of the levels of virus-specific RNA 
      quantitated in each strain showed no direct relationship between the presence of 
      a particular endogenous provirus or with increasing numbers of proviruses. 
      Association of specific genetic markers with the level of MMTV-specific RNA was 
      examined by using multiple regression analysis. Several cellular loci as well as 
      proviral loci were identified that were significantly associated with viral 
      expression. Importantly, these cellular loci associated with MMTV expression 
      segregated independently of viral sequences.
FAU - Traina-Dorge, V L
AU  - Traina-Dorge VL
FAU - Carr, J K
AU  - Carr JK
FAU - Bailey-Wilson, J E
AU  - Bailey-Wilson JE
FAU - Elston, R C
AU  - Elston RC
FAU - Taylor, B A
AU  - Taylor BA
FAU - Cohen, J C
AU  - Cohen JC
LA  - eng
GR  - R01-CA-28198/CA/NCI NIH HHS/United States
GR  - R01-CA-34823/CA/NCI NIH HHS/United States
GR  - R01-GM-18684/GM/NIGMS NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Genetics
JT  - Genetics
JID - 0374636
RN  - 0 (Lipopolysaccharides)
RN  - 0 (RNA, Viral)
SB  - IM
MH  - Alleles
MH  - Animals
MH  - Cell Transformation, Neoplastic
MH  - Female
MH  - Genes, Viral
MH  - Lipopolysaccharides/pharmacology
MH  - Mammary Tumor Virus, Mouse/drug effects/*genetics
MH  - Mice
MH  - Mice, Inbred Strains
MH  - Nucleic Acid Hybridization
MH  - *Oncogenes
MH  - RNA, Viral/genetics/isolation & purification
MH  - Species Specificity
MH  - *Transcription, Genetic
PMC - PMC1202660
EDAT- 1985/11/01 00:00
MHDA- 1985/11/01 00:01
PMCR- 1986/02/01
CRDT- 1985/11/01 00:00
PHST- 1985/11/01 00:00 [pubmed]
PHST- 1985/11/01 00:01 [medline]
PHST- 1985/11/01 00:00 [entrez]
PHST- 1986/02/01 00:00 [pmc-release]
AID - 10.1093/genetics/111.3.597 [doi]
PST - ppublish
SO  - Genetics. 1985 Nov;111(3):597-615. doi: 10.1093/genetics/111.3.597.