PMID- 29975560
OWN - NLM
STAT- MEDLINE
DCOM- 20181009
LR  - 20181009
IS  - 1744-8344 (Electronic)
IS  - 1477-9072 (Linking)
VI  - 16
IP  - 8
DP  - 2018 Aug
TI  - The use of hemodynamics to predict mortality in patients undergoing primary PCI 
      for ST-elevation myocardial infarction.
PG  - 551-557
LID - 10.1080/14779072.2018.1497484 [doi]
AB  - Challenges remain in predicting mortality and severe myocardial dysfunction in 
      patients undergoing primary percutaneous coronary intervention (PPCI) for ST 
      elevation myocardial infarction (STEMI). Areas covered: Cardiogenic shock is 
      associated with a high mortality rate. Less well characterized are patients who 
      are not in cardiogenic shock but will die from pump failure as a result of a 
      STEMI. There is a long history of using hemodynamics to risk stratify patients 
      with acute MI with the Killip class being shown to provide prognostic information 
      in the prereperfusion, thrombolytic and PPCI eras. Recent studies have identified 
      low systolic blood pressure (SBP), elevated heart rate, elevated left ventricular 
      end diastolic pressure (LVEDP), and low SBP/LVEDP ratio as hemodynamic parameters 
      associated with early mortality in patients undergoing PPCI. Although 
      infrequently used, prognostic information can be obtained from right heart 
      catheterization in the setting of STEMI with the best-studied parameters being 
      cardiac power, pulmonary capillary wedge pressure (PCWP), cardiac output, right 
      atrial pressure/PCWP ratio, and pulmonary artery pulsatility index. Expert 
      commentary: Hemodynamic parameters measured at the time of PPCI provide important 
      prognostic information. Whether hemodynamics can be used to determine which 
      patients benefit from early initiation of mechanical support remains to be 
      determined.
FAU - Goins, Allie E
AU  - Goins AE
AD  - a Division of Cardiology and McAllister Heart Institute , University of North 
      Carolina , Chapel Hill , NC , USA.
FAU - Rayson, Robert
AU  - Rayson R
AD  - a Division of Cardiology and McAllister Heart Institute , University of North 
      Carolina , Chapel Hill , NC , USA.
FAU - Yeung, Michael
AU  - Yeung M
AD  - a Division of Cardiology and McAllister Heart Institute , University of North 
      Carolina , Chapel Hill , NC , USA.
FAU - Stouffer, George A
AU  - Stouffer GA
AD  - a Division of Cardiology and McAllister Heart Institute , University of North 
      Carolina , Chapel Hill , NC , USA.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20180713
PL  - England
TA  - Expert Rev Cardiovasc Ther
JT  - Expert review of cardiovascular therapy
JID - 101182328
RN  - 0 (Fibrinolytic Agents)
SB  - IM
MH  - Cardiac Catheterization
MH  - Fibrinolytic Agents/adverse effects/therapeutic use
MH  - *Hemodynamics
MH  - Humans
MH  - Percutaneous Coronary Intervention/adverse effects/*methods
MH  - Prognosis
MH  - ST Elevation Myocardial Infarction/mortality/physiopathology/*therapy
MH  - Shock, Cardiogenic/mortality
MH  - Treatment Outcome
OTO - NOTNLM
OT  - STEMI
OT  - hemodynamics
OT  - left ventricular end diastolic pressure
OT  - primary angioplasty
OT  - systolic blood pressure
EDAT- 2018/07/06 06:00
MHDA- 2018/10/10 06:00
CRDT- 2018/07/06 06:00
PHST- 2018/07/06 06:00 [pubmed]
PHST- 2018/10/10 06:00 [medline]
PHST- 2018/07/06 06:00 [entrez]
AID - 10.1080/14779072.2018.1497484 [doi]
PST - ppublish
SO  - Expert Rev Cardiovasc Ther. 2018 Aug;16(8):551-557. doi: 
      10.1080/14779072.2018.1497484. Epub 2018 Jul 13.