PMID- 29975601
OWN - NLM
STAT- MEDLINE
DCOM- 20191121
LR  - 20191121
IS  - 1522-1601 (Electronic)
IS  - 0161-7567 (Linking)
VI  - 125
IP  - 4
DP  - 2018 Oct 1
TI  - Effect of quantity and quality of pre-exercise carbohydrate meals on central 
      fatigue.
PG  - 1021-1029
LID - 10.1152/japplphysiol.00221.2018 [doi]
AB  - Both the quantity and quality of pre-exercise carbohydrate (CHO) meals have been 
      shown to improve endurance performance. However, their role in attenuating 
      central fatigue (CF) is inconclusive. The use of neurophysiological techniques, 
      such as voluntary activation (VA) and the central activation ratio (CAR), 
      alongside maximum voluntary contraction (MVC) and sustained MVC (sMVC) can 
      provide information on CF. Hence, the objective of this study was to investigate 
      the effects of isocaloric pre-exercise meals: 1) a high versus low quantity of 
      CHO and 2) a high quantity of CHO with a high versus low glycemic index (GI) on 
      MVC, VA, and CAR following a 90-min run. The high and low quantity of CHO was 1.5 
      and 0.8 g/kg body wt, respectively, and high and low GI was ~75 and ~40, 
      respectively. Blood insulin, serotonin, tryptophan, and gaseous exchange were 
      also measured. High CHO preserved sMVC, VA, CAR, and serotonin postrunning with 
      greater CHO oxidation and insulin response, whereas in low CHO, greater 
      reductions in sMVC, VA, and CAR were accompanied by higher serotonin and fat 
      oxidation with lower insulin response. These observations indicate central 
      involvements. Meanwhile, high GI CHO better preserved force (sMVC), CAR, and 
      tryptophan with greater CHO oxidation and insulin response compared with low GI. 
      The findings of this study suggest that pre-exercise meals with varying quantity 
      and quality of CHO can have an effect on CF, where greater CHO oxidation and 
      insulin response found in both high CHO and high GI lead to attenuation of CF. 
      NEW & NOTEWORTHY This paper examined the effects of carbohydrate interventions 
      (high and low: quantity and quality wise) on central activity during prolonged 
      exercise using mainly neurophysiological techniques along with gaseous exchange 
      and blood insulin, serotonin, and tryptophan data.
FAU - Khong, Teng Keen
AU  - Khong TK
AD  - Centre of Sports and Exercise Sciences, University of Malaya , Kuala Lumpur , 
      Malaysia.
AD  - Department of Sports Sciences, Faculty of Applied Sciences, Tunku Abdul Rahman 
      University College , Kuala Lumpur , Malaysia.
FAU - Selvanayagam, Victor S
AU  - Selvanayagam VS
AD  - Centre of Sports and Exercise Sciences, University of Malaya , Kuala Lumpur , 
      Malaysia.
FAU - Hamzah, Sareena Hanim
AU  - Hamzah SH
AD  - Centre of Sports and Exercise Sciences, University of Malaya , Kuala Lumpur , 
      Malaysia.
FAU - Yusof, Ashril
AU  - Yusof A
AD  - Centre of Sports and Exercise Sciences, University of Malaya , Kuala Lumpur , 
      Malaysia.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20180705
PL  - United States
TA  - J Appl Physiol (1985)
JT  - Journal of applied physiology (Bethesda, Md. : 1985)
JID - 8502536
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Insulin)
RN  - 333DO1RDJY (Serotonin)
RN  - 8DUH1N11BX (Tryptophan)
SB  - IM
MH  - Adult
MH  - Cross-Over Studies
MH  - *Diet, Carbohydrate-Restricted
MH  - *Dietary Carbohydrates
MH  - Exercise
MH  - Fatigue/*prevention & control
MH  - *Glycemic Index
MH  - Humans
MH  - Insulin/blood
MH  - Male
MH  - Muscle Contraction
MH  - Oxidation-Reduction
MH  - *Physical Endurance
MH  - Serotonin/blood
MH  - Tryptophan/blood
MH  - Young Adult
OTO - NOTNLM
OT  - carbohydrate
OT  - central activation ratio
OT  - central fatigue
OT  - glycemic index
OT  - maximal voluntary force
EDAT- 2018/07/06 06:00
MHDA- 2019/11/22 06:00
CRDT- 2018/07/06 06:00
PHST- 2018/07/06 06:00 [pubmed]
PHST- 2019/11/22 06:00 [medline]
PHST- 2018/07/06 06:00 [entrez]
AID - 10.1152/japplphysiol.00221.2018 [doi]
PST - ppublish
SO  - J Appl Physiol (1985). 2018 Oct 1;125(4):1021-1029. doi: 
      10.1152/japplphysiol.00221.2018. Epub 2018 Jul 5.