PMID- 29978011
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220318
IS  - 2364-3722 (Print)
IS  - 2196-9736 (Electronic)
IS  - 2196-9736 (Linking)
VI  - 6
IP  - 7
DP  - 2018 Jul
TI  - EUS-guided sampling with 25G biopsy needle as a rescue strategy for diagnosis of 
      small subepithelial lesions of the upper gastrointestinal tract.
PG  - E892-E897
LID - 10.1055/a-0603-3578 [doi]
AB  - BACKGROUND AND STUDY AIMS:  This study was designed to evaluate the impact of 
      additional tissue obtained with endoscopic ultrasound (EUS)-guided 25-gauge core 
      biopsy needle (25G-PC) following an unsuccessful fine-needle biopsy (FNB) 
      performed with larger-bore needles for the characterization of gastrointestinal 
      subepithelial lesions (GI-SELs). PATIENTS AND METHODS:  We prospectively 
      collected and retrospectively analyzed information in our database from January 
      2013 to June 2017 for all patients with GI-SELs who received a EUS-guided FNB 
      (EUS-FNB) with 25G-PC during the same procedure after failure of biopsy performed 
      with larger-bore needle. Diagnostic yield, diagnostic accuracy and procedural 
      complications were evaluated. RESULTS: Sixteen patients were included in this 
      study, 10 men and 6 women, median age 67.8 (range 43 to 76 years). Five patients 
      were found to have a SEL localized in the distal duodenum, five in the gastric 
      antrum, two in the gastric fundus and four in the gastric body. The mean size of 
      the lesions was 20.5 mm (range 18 - 24 mm). EUS-FNB with 25G-PC enabled final 
      diagnosis in nine patients (56.2 %). Regarding the subgroup of duodenal lesions, 
      the procedure was successful in four of five (80 %). Final diagnoses with 
      EUS-guided sampling were GIST (n = 6), leiomyoma (n = 2) and metastatic ovarian 
      carcinoma (n = 1). No procedure-related complications were recorded. CONCLUSION: 
       In patients with small GI-SELs, additional tissue obtained with 25G-PC could 
      represents a "rescue" strategy after an unsuccessful procedure with larger-bore 
      needles, especially when lesions are localized in the distal duodenum.
FAU - Antonini, Filippo
AU  - Antonini F
AD  - Department of Gastroenterology, A. Murri Hospital, Polytechnic University of 
      Marche, Fermo, Italy.
FAU - Giorgini, Sara
AU  - Giorgini S
AD  - Pathological Anatomy and Histopathology, Department of Biomedical Sciences and 
      Public Health, Polytechnic University of Marche, Ancona, Italy.
FAU - Fuccio, Lorenzo
AU  - Fuccio L
AD  - Department of Medical and Surgical Sciences, S. Orsola-Malpighi Hospital, 
      University of Bologna, Bologna, Italy.
FAU - Angelelli, Lucia
AU  - Angelelli L
AD  - Medical Oncology, Mazzoni Hospital, Ascoli Piceno, Italy.
FAU - Macarri, Giampiero
AU  - Macarri G
AD  - Department of Gastroenterology, A. Murri Hospital, Polytechnic University of 
      Marche, Fermo, Italy.
LA  - eng
PT  - Journal Article
DEP - 20180704
PL  - Germany
TA  - Endosc Int Open
JT  - Endoscopy international open
JID - 101639919
PMC - PMC6032639
COIS- Competing interests None
EDAT- 2018/07/07 06:00
MHDA- 2018/07/07 06:01
PMCR- 2018/07/01
CRDT- 2018/07/07 06:00
PHST- 2018/01/06 00:00 [received]
PHST- 2018/03/13 00:00 [accepted]
PHST- 2018/07/07 06:00 [entrez]
PHST- 2018/07/07 06:00 [pubmed]
PHST- 2018/07/07 06:01 [medline]
PHST- 2018/07/01 00:00 [pmc-release]
AID - 10.1055/a-0603-3578 [doi]
PST - ppublish
SO  - Endosc Int Open. 2018 Jul;6(7):E892-E897. doi: 10.1055/a-0603-3578. Epub 2018 Jul 
      4.