PMID- 29978346
OWN - NLM
STAT- MEDLINE
DCOM- 20181211
LR  - 20220409
IS  - 1573-2649 (Electronic)
IS  - 0962-9343 (Linking)
VI  - 27
IP  - 11
DP  - 2018 Nov
TI  - Psychometric properties of the EQ-5D-5L in patients with hip or knee 
      osteoarthritis: reliability, validity and responsiveness.
PG  - 2897-2908
LID - 10.1007/s11136-018-1929-x [doi]
AB  - PURPOSE: To study the psychometric properties, including reliability, validity 
      and responsiveness, of the Spanish EQ-5D-5L questionnaire for patients with hip 
      or knee osteoarthritis (OA). METHODS: We included 758 patients with hip or knee 
      OA who completed the EQ-5D-5L and Western Ontario and McMaster Universities 
      Osteoarthritis Index (WOMAC) at baseline, of whom 644 also did 6 months later. 
      The EQ-5D-5L contains five questions from which a utility index is derived. The 
      WOMAC covers three dimensions: pain, stiffness and physical function. Floor and 
      ceiling effects were calculated. Reliability was assessed using Cronbach's alpha. 
      Convergent validity was tested using the Spearman correlation coefficient between 
      EQ-5D-5L and WOMAC. We examined known-groups validity by comparing the EQ-5D-5L 
      between subgroups defined by WOMAC scores using ANOVA or the Kruskal-Wallis test. 
      Effect sizes were calculated to assess responsiveness, and minimal clinically 
      important difference (MCID) was estimated. RESULTS: The EQ-5D-5L showed minimal 
      floor and ceiling effects (< 3%). Cronbach's alpha was 0.86. The EQ-5D-5L index 
      was strongly correlated with WOMAC pain and function scores (- 0.688 and 
      - 0.782). Patients with higher WOMAC scores had significantly (p < 0.0001) lower 
      EQ-5D-5L index. The 20.19% had hip or knee replacement during the follow-up. 
      Effect sizes were small among non-surgical patients, but > 0.80 among "improved" 
      surgical patients, being the MCID for improvement 0.32 points. CONCLUSIONS: The 
      results support the reliability, validity and responsiveness of the EQ-5D-5L, 
      overcoming the limitations of the EQ-5D-3L in these patients. Therefore, the 
      EQ-5D-5L could be very useful as an outcome measure, at least in patients with 
      hip or knee OA.
FAU - Bilbao, Amaia
AU  - Bilbao A
AUID- ORCID: 0000-0002-2202-0753
AD  - Research Unit, Basurto University Hospital (Osakidetza), Avda. Montevideo, 18, 
      48013, Bilbao, Bizkaia, Spain. amaia.bilbaogonzalez@osakidetza.eus.
AD  - Health Service Research Network on Chronic Diseases (REDISSEC), Bilbao, Spain. 
      amaia.bilbaogonzalez@osakidetza.eus.
FAU - Garcia-Perez, Lidia
AU  - Garcia-Perez L
AD  - Health Service Research Network on Chronic Diseases (REDISSEC), Bilbao, Spain.
AD  - Canary Foundation for Health Research (FUNCANIS), La Laguna, Tenerife, Spain.
FAU - Arenaza, Juan Carlos
AU  - Arenaza JC
AD  - Health Service Research Network on Chronic Diseases (REDISSEC), Bilbao, Spain.
AD  - Traumatology and Orthopedic Surgery Service, Basurto University Hospital 
      (Osakidetza), Bilbao, Bizkaia, Spain.
FAU - Garcia, Isidoro
AU  - Garcia I
AD  - Traumatology and Orthopedic Surgery Service, Galdakao-Usansolo Hospital 
      (Osakidetza), Galdakao, Bizkaia, Spain.
FAU - Ariza-Cardiel, Gloria
AU  - Ariza-Cardiel G
AD  - Health Service Research Network on Chronic Diseases (REDISSEC), Bilbao, Spain.
AD  - Multiprofessional Teaching Unit of Primary and Community Care, Primary Healthcare 
      Management, Madrid Health Service, Madrid, Spain.
FAU - Trujillo-Martin, Elisa
AU  - Trujillo-Martin E
AD  - Rheumatology Service, University Hospital of the Canary Islands, Tenerife, Spain.
FAU - Forjaz, Maria Joao
AU  - Forjaz MJ
AD  - Health Service Research Network on Chronic Diseases (REDISSEC), Bilbao, Spain.
AD  - Carlos III Health Institute, National School of Public Health, Madrid, Spain.
FAU - Martin-Fernandez, Jesus
AU  - Martin-Fernandez J
AD  - Health Service Research Network on Chronic Diseases (REDISSEC), Bilbao, Spain.
AD  - Villamanta Clinic, Navalcarnero Health Centre, Madrid Health Service, Madrid, 
      Spain.
AD  - Health Sciences Faculty, Rey Juan Carlos University, Madrid, Spain.
LA  - eng
GR  - PI13/00560/Instituto de Salud Carlos III/
GR  - PI13/00518/Instituto de Salud Carlos III/
GR  - PI13/00648/Instituto de Salud Carlos III/
PT  - Journal Article
DEP - 20180705
PL  - Netherlands
TA  - Qual Life Res
JT  - Quality of life research : an international journal of quality of life aspects of 
      treatment, care and rehabilitation
JID - 9210257
SB  - IM
MH  - Aged
MH  - Female
MH  - Humans
MH  - Male
MH  - *Minimal Clinically Important Difference
MH  - Osteoarthritis, Hip/*diagnosis
MH  - Osteoarthritis, Knee/*diagnosis
MH  - Outcome Assessment, Health Care
MH  - Pain Measurement/*methods
MH  - Psychometrics/*methods
MH  - Quality of Life/*psychology
MH  - Reproducibility of Results
MH  - Surveys and Questionnaires
OTO - NOTNLM
OT  - EQ-5D-5L
OT  - Minimal clinically important difference
OT  - Osteoarthritis
OT  - Psychometric properties
OT  - Utility index
EDAT- 2018/07/07 06:00
MHDA- 2018/12/12 06:00
CRDT- 2018/07/07 06:00
PHST- 2018/07/03 00:00 [accepted]
PHST- 2018/07/07 06:00 [pubmed]
PHST- 2018/12/12 06:00 [medline]
PHST- 2018/07/07 06:00 [entrez]
AID - 10.1007/s11136-018-1929-x [pii]
AID - 10.1007/s11136-018-1929-x [doi]
PST - ppublish
SO  - Qual Life Res. 2018 Nov;27(11):2897-2908. doi: 10.1007/s11136-018-1929-x. Epub 
      2018 Jul 5.