PMID- 29983917
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 2046-1402 (Print)
IS  - 2046-1402 (Electronic)
IS  - 2046-1402 (Linking)
VI  - 7
DP  - 2018
TI  - Development of a human leukocyte antigen-based HIV vaccine.
LID - F1000 Faculty Rev-874 [pii]
LID - 10.12688/f1000research.13759.1 [doi]
AB  - Human immunodeficiency virus (HIV) carries abundant human cell proteins, 
      particularly human leukocyte antigen (HLA) molecules when the virus leaves host 
      cells. Immunization in macaques with HLAs protects the animals from simian 
      immunodeficiency virus infection. This finding offers an alternative approach to 
      the development of HLA molecule-based HIV vaccines. Decades of studies have 
      enhanced a great deal of our understanding of the mechanisms of allo-immune 
      response-mediated anti-HIV immunity. These include cell-mediated immunity, innate 
      immunity, and antibody response. These studies provided a rationale for the 
      future design of effective HIV vaccines.
FAU - Wang, Yufei
AU  - Wang Y
AUID- ORCID: 0000-0003-0346-0099
AD  - Mucosal Immunology Unit, Dental Institute, Kings College London, Guy's Campus, 
      London Bridge, London, SE1 9RT, UK.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20180622
PL  - England
TA  - F1000Res
JT  - F1000Research
JID - 101594320
PMC - PMC6020720
OTO - NOTNLM
OT  - HIV vaccines
OT  - HLA
OT  - allogeneic immune response
COIS- No competing interests were disclosed.No competing interests were disclosed.No 
      competing interests were disclosed.
EDAT- 2018/07/10 06:00
MHDA- 2018/07/10 06:01
PMCR- 2018/06/22
CRDT- 2018/07/10 06:00
PHST- 2018/06/18 00:00 [accepted]
PHST- 2018/07/10 06:00 [entrez]
PHST- 2018/07/10 06:00 [pubmed]
PHST- 2018/07/10 06:01 [medline]
PHST- 2018/06/22 00:00 [pmc-release]
AID - F1000 Faculty Rev-874 [pii]
AID - 10.12688/f1000research.13759.1 [doi]
PST - epublish
SO  - F1000Res. 2018 Jun 22;7:F1000 Faculty Rev-874. doi: 
      10.12688/f1000research.13759.1. eCollection 2018.