PMID- 29989889
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240416
IS  - 1911-6470 (Print)
IS  - 1920-1214 (Electronic)
IS  - 1911-6470 (Linking)
VI  - 12
IP  - 11
DP  - 2018 Nov
TI  - Prevalence estimates for lower urinary tract symptom severity among men in Uganda 
      and sub-Saharan Africa based on regional prevalence data.
PG  - E447-E452
LID - 10.5489/cuaj.5105 [doi]
AB  - INTRODUCTION: In the absence of specific regional data, the prevalence of urinary 
      symptoms in the developing world is currently estimated. Regional prevalence data 
      and estimates based on them have relevance for accurate planning/provision of 
      future healthcare. We sought to extrapolate prevalence estimates for lower 
      urinary tract symptom (LUTS) severity and associated sexual dysfunction for 
      Uganda as a whole and sub-Saharan Africa (SSA) using newly available regional 
      data from a community-based cohort of men in Uganda. METHODS: Global Burden of 
      Disease Study (GBDS) population statistics were applied to a regional dataset to 
      provide prevalence estimates for Uganda and SSA; 415 men >55 years from five 
      rural Ugandan communities had completed the International Prostate Symptom Scale 
      (IPSS) and Epstein inventory to grade their LUTS severity and satisfaction with 
      sexual function. RESULTS: Prevalence rates for moderate and severe LUTS were 
      40.5% and 20%, respectively, in men >55 in the Ugandan regional data; associated 
      scores for all four Epstein sexual satisfaction measures were low. GBDS 
      population figures (2016) for men >55 years are 942 115 (Uganda) and 33.9 million 
      (SSA); hence, scaling up from regional prevalence data suggests 381 557 and 188 
      423 men >55 years in Uganda, and 13 729 500 and 6 780 000 in SSA have moderate 
      and severe LUTS, respectively, and the majority will have compromise of elements 
      of their sexual function. CONCLUSIONS: Extrapolation from a small regional 
      dataset (for which we have no guarantee of national or SSA representability) 
      provides the first prevalence estimates for LUTS severity based on African data, 
      and suggests a large proportion of men >55 years are troubled with LUTS and 
      associated sexual dysfunction.
FAU - Bajunirwe, Francis
AU  - Bajunirwe F
AD  - Department of Community Health, Mbarara University of Science and Technology, 
      Mbarara, Uganda.
FAU - Stothers, Lynn
AU  - Stothers L
AD  - Department of Urologic Sciences, and Associate Member School of Population and 
      Public Health Division of Global Health, University of British Columbia, 
      Vancouver, BC, Canada, and Principal Investigator, International Collaboration on 
      Repair Discoveries (ICORD).
FAU - Berkowitz, Jonathan
AU  - Berkowitz J
AD  - Department of Family Practice, Sauder School of Business, University of British 
      Columbia, Vancouver, BC, Canada.
FAU - Macnab, Andrew J
AU  - Macnab AJ
AD  - Stellenbosch Institute for Advanced Study, Wallenberg Research Centre, 
      Stellenbosch, South Africa, and Department of Urologic Sciences, University of 
      British Columbia, Vancouver, BC, Canada.
LA  - eng
PT  - Journal Article
DEP - 20180608
PL  - Canada
TA  - Can Urol Assoc J
JT  - Canadian Urological Association journal = Journal de l'Association des urologues 
      du Canada
JID - 101312644
PMC - PMC6217950
COIS- Competing interests: The authors report no competing personal or financial 
      interests.
EDAT- 2018/07/11 06:00
MHDA- 2018/07/11 06:01
PMCR- 2018/11/01
CRDT- 2018/07/11 06:00
PHST- 2018/07/11 06:00 [pubmed]
PHST- 2018/07/11 06:01 [medline]
PHST- 2018/07/11 06:00 [entrez]
PHST- 2018/11/01 00:00 [pmc-release]
AID - cuaj.5105 [pii]
AID - cuaj-11-e447 [pii]
AID - 10.5489/cuaj.5105 [doi]
PST - ppublish
SO  - Can Urol Assoc J. 2018 Nov;12(11):E447-E452. doi: 10.5489/cuaj.5105. Epub 2018 
      Jun 8.