PMID- 29990412 OWN - NLM STAT- MEDLINE DCOM- 20190426 LR - 20190426 IS - 0038-3317 (Print) IS - 0038-3317 (Linking) VI - 71 IP - 2 DP - 2018 Feb TI - Successful Resolution of a Large Left Ventricular Thrombus with Rivaroxaban Therapy after Acute Myocardial Infarction. PG - 62-63 AB - Left ventricular (LV) thrombus is a major complication of acute systolic cardiomyopathy especially after a large anterior myocardial infarction (AMI), and it poses a significant embolic risk, up to five times higher than the general population. Current guidelines for LV thrombi recommend vitamin K antagonist for anticoagulation in contrast to novel oral anticoagulants (NOACs) which have not been studied well in cases of LV thrombus. We present a case of patient with AMI, who was noted to have severe systolic dysfunction and a large LV thrombus which was successfully treated with rivaroxaban therapy with complete resolution of LV thrombus on two months follow-up. CI - Copyright(c) South Dakota State Medical Association. FAU - Bhatnagar, Udit Bhaskar AU - Bhatnagar UB AD - Department of Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota. FAU - Rezkalla, Josh AU - Rezkalla J AD - University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota. FAU - Sethi, Prince AU - Sethi P AD - Department of Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota. FAU - Stys, Adam AU - Stys A AD - Division of Cardiology, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota. AD - Interventional Cardiology Fellowship Program, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota. LA - eng PT - Case Reports PL - United States TA - S D Med JT - South Dakota medicine : the journal of the South Dakota State Medical Association JID - 101265265 RN - 0 (Anticoagulants) RN - 9NDF7JZ4M3 (Rivaroxaban) SB - IM MH - Administration, Oral MH - Anticoagulants/administration & dosage/*therapeutic use MH - Heart Diseases/*drug therapy/etiology MH - Humans MH - Myocardial Infarction/*complications MH - Rivaroxaban/administration & dosage/*therapeutic use MH - Thrombosis/*drug therapy/etiology MH - Time Factors EDAT- 2018/07/11 06:00 MHDA- 2019/04/27 06:00 CRDT- 2018/07/11 06:00 PHST- 2018/07/11 06:00 [entrez] PHST- 2018/07/11 06:00 [pubmed] PHST- 2019/04/27 06:00 [medline] PST - ppublish SO - S D Med. 2018 Feb;71(2):62-63.