PMID- 29994663
OWN - NLM
STAT- MEDLINE
DCOM- 20190311
LR  - 20190311
IS  - 1940-9990 (Electronic)
IS  - 1932-4545 (Linking)
VI  - 12
IP  - 4
DP  - 2018 Aug
TI  - A Parasitic Insensitive Catheter-Based Capacitive Force Sensor for Cardiovascular 
      Diagnosis.
PG  - 812-823
LID - 10.1109/TBCAS.2018.2832172 [doi]
AB  - This paper presents a catheter-based capacitive force sensor interface for 
      cardiovascular diagnosis. The force sensor is implemented on a flexible printed 
      circuit board (FPCB) substrate with a force-sensitive polydimethylsiloxane 
      (PDMS), and a force-induced change in a capacitance of the sensor is measured by 
      a precision capacitive sensor interface. To recover the performance degradation 
      caused by the large parasitic capacitance $\rm C_\rm P$ of a long catheter, 
      we present a parasitic insensitive analog front-end (AFE) with active $\rm 
      C_\rm P$ cancellation, which employs a charge amplifier and a negative 
      capacitor at the virtual ground of the charge amplifier. The prototype sensor was 
      measured with a force loader in whole blood. The proposed AFE successfully 
      cancels $\rm C_\rm P$ of 348 pF in a 0.9-m-long sensor and measurement 
      results show the SNR of 53.8 dB and the capacitance resolution of 16 aF, a 
      19.6 dB improvement by canceling nonideal effect of $\rm C_\rm P$ . This 
      corresponds to a force resolution of 2.22 gf, which is 9.29 $\times$ reduction 
      compared to the work without the $\rm C_\rm P$ cancellation. The proposed 
      sensor interface is insensitive to $\rm C_\rm P$ from hundreds to 1-nF level, 
      and the force-dependent stiffness of two different tissues has been successfully 
      distinguished with an ex-vivo experiment. The proposed sensor interface enables 
      the integration of capacitive force sensors in a smart catheter.
FAU - Jeon, Sangkuk
AU  - Jeon S
FAU - Lee, JiYong
AU  - Lee J
FAU - Hwang, Hyunseok
AU  - Hwang H
FAU - Ryu, WonHyoung
AU  - Ryu W
FAU - Chae, Youngcheol
AU  - Chae Y
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180615
PL  - United States
TA  - IEEE Trans Biomed Circuits Syst
JT  - IEEE transactions on biomedical circuits and systems
JID - 101312520
SB  - IM
MH  - Biosensing Techniques/*methods
MH  - *Catheters
MH  - *Electric Capacitance
MH  - Equipment Design
EDAT- 2018/07/12 06:00
MHDA- 2019/03/12 06:00
CRDT- 2018/07/12 06:00
PHST- 2018/07/12 06:00 [pubmed]
PHST- 2019/03/12 06:00 [medline]
PHST- 2018/07/12 06:00 [entrez]
AID - 10.1109/TBCAS.2018.2832172 [doi]
PST - ppublish
SO  - IEEE Trans Biomed Circuits Syst. 2018 Aug;12(4):812-823. doi: 
      10.1109/TBCAS.2018.2832172. Epub 2018 Jun 15.