PMID- 29995063 OWN - NLM STAT- MEDLINE DCOM- 20180719 LR - 20221207 IS - 1807-3107 (Electronic) IS - 1806-8324 (Linking) VI - 32 DP - 2018 Jul 10 TI - Stability and bone loss around submerged and non-submerged implants in diabetic and non-diabetic patients: a 7-year follow-up. PG - e57 LID - S1806-83242018000100249 [pii] LID - 10.1590/1807-3107bor-2018.vol32.0057 [doi] AB - To evaluate peri-implant bone loss (PIBL) and stability around submerged and non-submerged dental implants in patients with and without type 2 diabetes mellitus (T2DM). Thirty-five T2DM and non-diabetic (NT2DM) patients were included in this study. Demographic data were recorded using a questionnaire and PIBL was measured on digital radiographs. Resonance frequency analysis (RFA) was carried out for each implant at the time of fixture placement and at 3 months in both groups. P values less than 0.05 were considered statistically significant. One hundred and eighteen dental implants with a mean height of 10 to 12 mm and 3.3 to 4.1 mm in diameter were placed. The comparison of the mean RFA values at baseline and at 3 months was statistically significant (p = 0.008) in T2DM patients. The inter-group mean RFA values at baseline and at 3 months were not significant (p > 0.05). PIBL was significantly high in T2DM as compared to NT2DM patients at each follow-up (p < 0.05). At 2, 3, and 7 years, non-submerged dental implants showed significantly high PIBL in T2DM patients as compared to NT2DM individuals (p<0.05). The results of the present clinical study demonstrate increased PIBL around non-submerged single-tooth implant-supported restorations in T2DM patients, which may be due to the immune inflammatory status. FAU - Al Zahrani, Saeed AU - Al Zahrani S AD - Ministry of National Guard Health Affairs, Division of Prosthodontics, Department of Dental Services, Riyadh, Saudi Arabia. FAU - Al Mutairi, Abdullah Abdulaziz AU - Al Mutairi AA AD - Ministry of National Guard Health Affairs, Division of Advanced Education in General Dentistry, Department of Dental Services, Riyadh, Saudi Arabia. LA - eng PT - Clinical Trial PT - Journal Article DEP - 20180710 PL - Brazil TA - Braz Oral Res JT - Brazilian oral research JID - 101307187 RN - 0 (Dental Implants) RN - 0 (Glycated Hemoglobin A) RN - 0 (hemoglobin A1c protein, human) SB - IM MH - Adult MH - Alveolar Bone Loss/etiology/*physiopathology MH - Bone-Implant Interface MH - Dental Implantation, Endosseous/*methods MH - *Dental Implants MH - Dental Prosthesis Design MH - Diabetes Mellitus, Type 2/complications/*physiopathology MH - Female MH - Follow-Up Studies MH - Glycated Hemoglobin/analysis MH - Humans MH - Male MH - Middle Aged MH - Osseointegration/physiology MH - Prospective Studies MH - Reference Values MH - Resonance Frequency Analysis MH - Statistics, Nonparametric MH - Time Factors MH - Treatment Outcome EDAT- 2018/07/12 06:00 MHDA- 2018/07/20 06:00 CRDT- 2018/07/12 06:00 PHST- 2017/09/17 00:00 [received] PHST- 2018/05/10 00:00 [accepted] PHST- 2018/07/12 06:00 [entrez] PHST- 2018/07/12 06:00 [pubmed] PHST- 2018/07/20 06:00 [medline] AID - S1806-83242018000100249 [pii] AID - 10.1590/1807-3107bor-2018.vol32.0057 [doi] PST - epublish SO - Braz Oral Res. 2018 Jul 10;32:e57. doi: 10.1590/1807-3107bor-2018.vol32.0057.