PMID- 29997426 OWN - NLM STAT- MEDLINE DCOM- 20181024 LR - 20190610 IS - 1945-5763 (Electronic) IS - 1082-0744 (Print) IS - 1082-0744 (Linking) VI - 24 IP - 3 DP - 2018 Summer TI - Comparison of Responsiveness and Minimal Clinically Important Difference of the Capabilities of Upper Extremity Test (CUE-T) and the Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP). PG - 227-238 LID - 10.1310/sci2403-227 [doi] AB - Background: The Capabilities of Upper Extremity Test (CUE-T) and the Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP) were both developed to detect change in upper extremity (UE) function in persons with tetraplegia. Objective: To compare the responsiveness and minimal clinically important difference (MCID) of the CUE-T and the quantitative prehension (QtP) scale of the GRASSP. Methods: Subjects included 69 persons with tetraplegia: 60 with acute and 9 with chronic injuries. Subjects were assessed twice 3 months apart using the CUE-T, QtP-GRASSP, and upper extremity motor scores (UEMS). Subjects rated their impression of change in overall and right/left UE function from -7 to +7. The standardized response mean (SRM) was determined for acute subjects. MCID was estimated using a small subjective change (2-3 points) and change in UEMS. Results: Subjects were 41.9 +/- 18.1 years old, neurological levels C1-C7; 25 were motor complete. For acute subjects, the SRMs for total/side CUE-T scores were 1.07/0.96, and for the QtP-GRASSP they were 0.88/0.78. MCIDs based on subjective change for total/side CUE-T scores were 11.7/6.1 points and for QtP-GRASSP were 6.4/3.0 points. Based on change in UEMS, MCIDs for total/side were 11.9/6.3 points for CUE-T and 6.0/3.3 points for QtP-GRASSP. Some subjects had changes in the CUE-T due to its arm items that were not seen with the QtP-GRASSP. Conclusion: Both the CUE-T and QtP-GRASSP are responsive to change in persons with acute cervical spinal cord injury with large SRMs. The CUE-T detects some changes in UE function not seen with the QtP-GRASSP. FAU - Marino, Ralph J AU - Marino RJ AD - Department of Rehabilitation Medicine, Sidney Kimmel Medical College, Jefferson (Philadelphia University + Thomas Jefferson University), Philadelphia, Pennsylvania. FAU - Sinko, Rebecca AU - Sinko R AD - Department of Occupational Therapy, Jefferson College of Health Professions, Jefferson (Philadelphia University + Thomas Jefferson University), Philadelphia, Pennsylvania. FAU - Bryden, Anne AU - Bryden A AD - Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio. FAU - Backus, Deborah AU - Backus D AD - Crawford Research Institute, Shepherd Center Hospital, Atlanta, Georgia. FAU - Chen, David AU - Chen D AD - Department of Physical Medicine and Rehabilitation, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. AD - Center for Rehabilitation Outcomes Research, Shirley Ryan AbilityLab, Chicago, Illinois. FAU - Nemunaitis, Gregory A AU - Nemunaitis GA AD - MetroHealth Medical Center/MetroHealth Rehabilitation Institute of Ohio, Cleveland, Ohio. AD - Department of Physical Medicine & Rehabilitation, Case Western Reserve University School of Medicine, Cleveland, Ohio. FAU - Leiby, Benjamin E AU - Leiby BE AD - Division of Biostatics, Department of Pharmacology and Experimental Therapeutics, Sidney Kimmel Medical College at, Jefferson (Philadelphia University + Thomas Jefferson University), Philadelphia, Pennsylvania. LA - eng PT - Comparative Study PT - Journal Article PL - United States TA - Top Spinal Cord Inj Rehabil JT - Topics in spinal cord injury rehabilitation JID - 9515174 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Cervical Vertebrae MH - *Disability Evaluation MH - Female MH - Hand Strength/*physiology MH - Humans MH - Male MH - Middle Aged MH - Minimal Clinically Important Difference MH - Quadriplegia/*physiopathology MH - Recovery of Function/physiology MH - Spinal Cord Injuries/*physiopathology MH - Upper Extremity/*physiopathology MH - Young Adult PMC - PMC6037321 OTO - NOTNLM OT - outcome assessment OT - tetraplegia OT - upper extremity COIS- Contact the corresponding author for information on how to obtain the CUE-T kit and testing instructions. Thomas Jefferson University and the Department of Rehabilitation Medicine receive payment for preparation and supply of the CUE-T kits if these are provided by the Department. Dr. Marino does not receive payment for the kits. The remaining authors have nothing to disclose. EDAT- 2018/07/13 06:00 MHDA- 2018/10/26 06:00 PMCR- 2019/06/01 CRDT- 2018/07/13 06:00 PHST- 2018/07/13 06:00 [entrez] PHST- 2018/07/13 06:00 [pubmed] PHST- 2018/10/26 06:00 [medline] PHST- 2019/06/01 00:00 [pmc-release] AID - 10.1310/sci2403-227 [doi] PST - ppublish SO - Top Spinal Cord Inj Rehabil. 2018 Summer;24(3):227-238. doi: 10.1310/sci2403-227.