PMID- 30003709 OWN - NLM STAT- MEDLINE DCOM- 20190318 LR - 20221207 IS - 1753-0407 (Electronic) IS - 1753-0407 (Linking) VI - 11 IP - 2 DP - 2019 Feb TI - SLEep among diabetic patients and their GlycaEmic control (SLEDGE): A pilot observational study. PG - 122-128 LID - 10.1111/1753-0407.12825 [doi] AB - BACKGROUND: Recent cohort studies have proven the association between sleep deprivation and adverse glycemic control (GC). The aim of this study was to assess the prevalence of excessive daytime sleepiness (EDS), a subjective measure of sleep deprivation, among type 2 diabetic mellitus (T2DM) patients and its association with GC. METHODS: This cross-sectional study was conducted between July 2015 and June 2016 in five diabetes clinics in the district of Erode, Tamil Nadu, India. An equal number of consenting patients with T2DM was recruited consecutively from each of the centers, and EDS was measured subjectively using the Epworth sleepiness scale (ESS), whereas GC was assessed using HbA1c levels. RESULTS: In all, 126 patients were screened and 102 were found eligible for the study. The prevalence of EDS was 17.5% (95% confidence interval 10.13-24.87). The association between ESS scores and HbA1c levels was analyzed using linear regression after adjusting for age, dietary intake, inflammatory markers (erythrocyte sedimentation rate), depression (Patient Health Questionnaire-9 score) and stress (Perceived Stress Scale score): for every unit increase in the ESS score, HbA1c increased by 0.143 g/dL (P < 0.001). CONCLUSION: Subjective EDS was seen in approximately one-quarter of patients with diabetes in our population. There was a positive association between EDS and glycemic control. Screening of patients with diabetes for EDS should be part of routine diabetes management. CI - (c) 2018 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and John Wiley & Sons Australia, Ltd. FAU - Raj, Jeffrey P AU - Raj JP AUID- ORCID: 0000-0002-8621-6106 AD - Church of South India Hospital, Erode, India. AD - Department of Pharmacology, St. John's Medical College, Bangalore, India. FAU - Hansdak, Samuel G AU - Hansdak SG AD - Department of General Medicine, Christian Medical College, Vellore, India. FAU - Naik, Dukhabandhu AU - Naik D AD - Department of Endocrinology, Christian Medical College, Vellore, India. FAU - Mahendri, Narayani V AU - Mahendri NV AD - Department of Dietetics and Nutrition, Christian Medical College, Vellore, India. FAU - Thomas, Nihal AU - Thomas N AD - Department of Endocrinology, Christian Medical College, Vellore, India. LA - eng GR - IRB Min NO 8995/Christian Medical College and Hospital (Vellore, India)/ PT - Journal Article PT - Multicenter Study PT - Observational Study DEP - 20180812 PL - Australia TA - J Diabetes JT - Journal of diabetes JID - 101504326 RN - 0 (Glycated Hemoglobin A) SB - IM MH - Adult MH - Cohort Studies MH - Cross-Sectional Studies MH - Diabetes Mellitus, Type 2/blood/epidemiology/*physiopathology MH - Female MH - Glycated Hemoglobin/*metabolism MH - Humans MH - India/epidemiology MH - Male MH - Middle Aged MH - Pilot Projects MH - Prevalence MH - Risk Factors MH - Sleep/*physiology MH - Sleep Deprivation/*physiopathology MH - Surveys and Questionnaires OTO - NOTNLM OT - diabetes mellitus OT - excessive day time iness OT - glycemic control OT - sleep OT - sleep deprivation OT - 白天过度嗜睡 OT - 睡眠 OT - 睡眠不足 OT - 糖尿病 OT - 血糖控制 EDAT- 2018/07/14 06:00 MHDA- 2019/03/19 06:00 CRDT- 2018/07/14 06:00 PHST- 2017/12/29 00:00 [received] PHST- 2018/05/27 00:00 [revised] PHST- 2018/07/09 00:00 [accepted] PHST- 2018/07/14 06:00 [pubmed] PHST- 2019/03/19 06:00 [medline] PHST- 2018/07/14 06:00 [entrez] AID - 10.1111/1753-0407.12825 [doi] PST - ppublish SO - J Diabetes. 2019 Feb;11(2):122-128. doi: 10.1111/1753-0407.12825. Epub 2018 Aug 12.