PMID- 30008398
OWN - NLM
STAT- MEDLINE
DCOM- 20190311
LR  - 20190311
IS  - 1873-7544 (Electronic)
IS  - 0306-4522 (Linking)
VI  - 386
DP  - 2018 Aug 21
TI  - Somatosensory Inputs Induced by Passive Movement Facilitate Primary Motor Cortex 
      Excitability Depending on the Interstimulus Interval, Movement Velocity, and 
      Joint Angle.
PG  - 194-204
LID - S0306-4522(18)30460-3 [pii]
LID - 10.1016/j.neuroscience.2018.06.042 [doi]
AB  - Somatosensory inputs affect primary motor cortex (M1) excitability; however, the 
      effect of movement-induced somatosensory inputs on M1 excitability is unknown. 
      This study examined whether M1 excitability is modulated by somatosensory inputs 
      with passive movement in 29 healthy subjects. Motor-evoked potentials (MEPs), 
      elicited by transcranial magnetic stimulation (TMS) were recorded from the first 
      dorsal interosseous (FDI) muscle (Experiment 1). M- and F-waves were measured 
      from the FDI muscle (Experiment 2). Passive movements of the index finger were 
      performed in the adduction direction. TMS pulses were preceded by starting 
      passive movements with interstimulus intervals (ISIs) of 30, 60, 90, 120, 150, 
      180, and 210 ms. TMS or electrical stimulation was performed in the midrange of 
      the metacarpophalangeal joint during passive movements. MEPs were significantly 
      facilitated at 90, 120, and 150 ms (p < 0.05). No M- or F-wave changes were 
      observed for any ISI. In addition, we investigated whether MEP changes were 
      dependent on passive movement velocity and joint angle. Passive movement was 
      performed at two movement velocities (Experiment 3) or joint angles (Experiment 
      4). MEP facilitation was observed depending on the movement velocities or joint 
      angles. These experiments demonstrated that somatosensory inputs induced by 
      passive movements facilitated M1 excitability depending on the ISIs, passive 
      movement velocity, and joint angle.
CI  - Copyright (c) 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.
FAU - Sasaki, Ryoki
AU  - Sasaki R
AD  - Institute for Human Movement and Medical Sciences, Niigata University of Health 
      and Welfare, Niigata City, Niigata, Japan. Electronic address: 
      hwd17005@nuhw.ac.jp.
FAU - Tsuiki, Shota
AU  - Tsuiki S
AD  - Institute for Human Movement and Medical Sciences, Niigata University of Health 
      and Welfare, Niigata City, Niigata, Japan.
FAU - Miyaguchi, Shota
AU  - Miyaguchi S
AD  - Institute for Human Movement and Medical Sciences, Niigata University of Health 
      and Welfare, Niigata City, Niigata, Japan.
FAU - Kojima, Sho
AU  - Kojima S
AD  - Institute for Human Movement and Medical Sciences, Niigata University of Health 
      and Welfare, Niigata City, Niigata, Japan.
FAU - Saito, Kei
AU  - Saito K
AD  - Institute for Human Movement and Medical Sciences, Niigata University of Health 
      and Welfare, Niigata City, Niigata, Japan.
FAU - Inukai, Yasuto
AU  - Inukai Y
AD  - Institute for Human Movement and Medical Sciences, Niigata University of Health 
      and Welfare, Niigata City, Niigata, Japan.
FAU - Otsuru, Naofumi
AU  - Otsuru N
AD  - Institute for Human Movement and Medical Sciences, Niigata University of Health 
      and Welfare, Niigata City, Niigata, Japan.
FAU - Onishi, Hideaki
AU  - Onishi H
AD  - Institute for Human Movement and Medical Sciences, Niigata University of Health 
      and Welfare, Niigata City, Niigata, Japan.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180704
PL  - United States
TA  - Neuroscience
JT  - Neuroscience
JID - 7605074
SB  - IM
MH  - Adult
MH  - Electric Stimulation/methods
MH  - Evoked Potentials, Motor/*physiology
MH  - Evoked Potentials, Somatosensory/*physiology
MH  - Female
MH  - Finger Joint/*physiology
MH  - Humans
MH  - Male
MH  - Motor Cortex/*physiology
MH  - Movement/*physiology
MH  - Transcranial Magnetic Stimulation/methods
MH  - Young Adult
OTO - NOTNLM
OT  - afferent facilitation
OT  - joint angle
OT  - motor-evoked potential
OT  - movement velocity
OT  - passive movement
OT  - somatosensory input
EDAT- 2018/07/17 06:00
MHDA- 2019/03/12 06:00
CRDT- 2018/07/17 06:00
PHST- 2018/01/19 00:00 [received]
PHST- 2018/06/01 00:00 [revised]
PHST- 2018/06/25 00:00 [accepted]
PHST- 2018/07/17 06:00 [pubmed]
PHST- 2019/03/12 06:00 [medline]
PHST- 2018/07/17 06:00 [entrez]
AID - S0306-4522(18)30460-3 [pii]
AID - 10.1016/j.neuroscience.2018.06.042 [doi]
PST - ppublish
SO  - Neuroscience. 2018 Aug 21;386:194-204. doi: 10.1016/j.neuroscience.2018.06.042. 
      Epub 2018 Jul 4.