PMID- 30010046
OWN - NLM
STAT- MEDLINE
DCOM- 20200103
LR  - 20200103
IS  - 1878-1632 (Electronic)
IS  - 1529-9430 (Linking)
VI  - 19
IP  - 1
DP  - 2019 Jan
TI  - Minimum clinically important difference of the health-related quality of life 
      scales in adult spinal deformity calculated by latent class analysis: is it 
      appropriate to use the same values for surgical and nonsurgical patients?
PG  - 71-78
LID - S1529-9430(18)30650-8 [pii]
LID - 10.1016/j.spinee.2018.07.005 [doi]
AB  - BACKGROUND CONTEXT: Health-related quality of life (HRQOL) parameters have been 
      shown to be reliable and valid in patients with adult spinal deformity (ASD). 
      Minimum clinically important difference (MCID) has become increasingly important 
      to clinicians in evaluating patients with a threshold of improvement that is 
      clinically relevant. PURPOSE: To calculate MCID and minimum detectable change 
      (MDC) values of total scores of the Core Outcome Measures Index (COMI), Oswestry 
      Disability Index (ODI), Physical Component Summary (PCS), Mental Component 
      Summary (MCS) of the Short Form 36 (SF-36), and Scoliosis Research Society 22R 
      (SRS-22R) in surgically and nonsurgically treated ASD patients who have completed 
      an anchor question at pretreatment and 1-year follow-up. STUDY DESIGN/SETTING: 
      Prospective cohort. PATIENT SAMPLE: Surgical and nonsurgical patients from a 
      multicenter ASD database. OUTCOME MEASURES: Self-reported HRQOL measures (COMI, 
      ODI, SF-36, SRS-22R, and anchor question). METHODS: A total of 185 surgical and 
      86 nonsurgical patients from a multicenter ASD database who completed 
      pretreatment and 1-year follow-up HRQOL scales and the anchor question at the 
      first year follow-up were included. The anchor question was used to determine 
      MCID for each HRQOL measure. MCIDs were calculated by an anchor-based method 
      using latent class analysis (LCA) and MDCs by a distribution-based method. 
      RESULTS: All differences between means of baseline and first year postoperative 
      total score measures for all scales demonstrated statistically significant 
      improvements in the overall population as well as the surgically treated patients 
      but not in the nonsurgical group. The calculated MDC and MCID values of HRQOL 
      parameters in the entire study population were 1.34 and 2.62 for COMI, 10.65 and 
      14.31 for ODI, 6.09 and 7.33 for SF-36 PCS, 6.14 and 4.37 for SF-36 MCS, and 0.42 
      and 0.71 for SRS-22R. The calculated MCID values for surgical and non-surgical 
      treatment groups were 2.76 versus 1.20 for COMI, 14.96 versus 2.45 for ODI, 7.83 
      versus 2.15 for SF-36 PCS, 5.14 versus 2.03 for SF-36 MCS, and 0.94 versus 0.11 
      for SRS-22R; the MDC values for surgical and nonsurgical treatment groups were 
      1.22 versus 1.51 for COMI, 10.27 versus 9.45 for ODI, 5.16 versus 6.77 for SF-36 
      PCS, 6.05 versus 5.67 for SF-36 MCS, and 0.38 versus 0.43 for SRS-22R. 
      CONCLUSIONS: This study has demonstrated that MCID calculations for the HRQOL 
      scales in ASD using LCA yield values comparable to other studies that had used 
      different methodologies. The most important finding was the significantly 
      different MCIDs for COMI, ODI, SF-36 PCS and SRS-22 in the surgically and 
      nonsurgically treated cohorts. This finding suggests that a universal MCID value, 
      inherent to a specific HRQOL for an entire cohort of ASD may not exist. Use of 
      different MCIDs for surgical and nonsurgical patients may be warranted.
CI  - Copyright (c) 2019 Elsevier Inc. All rights reserved.
FAU - Yuksel, Selcen
AU  - Yuksel S
AD  - Department of Biostatistics, Yildirim Beyazit University, Ankara, Turkey.
FAU - Ayhan, Selim
AU  - Ayhan S
AD  - ARTES Spine Center, Ankara, Turkey; Vocational School of Health Sciences, 
      Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
FAU - Nabiyev, Vugar
AU  - Nabiyev V
AD  - ARTES Spine Center, Ankara, Turkey.
FAU - Domingo-Sabat, Montse
AU  - Domingo-Sabat M
AD  - Hospital Universitari Vall d'Hebron, Barcelona, Spain.
FAU - Vila-Casademunt, Alba
AU  - Vila-Casademunt A
AD  - Hospital Universitari Vall d'Hebron, Barcelona, Spain.
FAU - Obeid, Ibrahim
AU  - Obeid I
AD  - Bordeaux University Hospital, Bordeaux, France.
FAU - Perez-Grueso, Francisco Sanchez
AU  - Perez-Grueso FS
AD  - Hospital Universitari La Paz, Madrid, Spain.
FAU - Acaroglu, Emre
AU  - Acaroglu E
AD  - Ankara Spine Center, Ankara, Turkey. Electronic address: acaroglue@gmail.com.
CN  - European Spine Study Group (ESSG)
AD  - Hospital Universitari Vall d'Hebron, Barcelona, Spain.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180827
PL  - United States
TA  - Spine J
JT  - The spine journal : official journal of the North American Spine Society
JID - 101130732
SB  - IM
MH  - Adult
MH  - Aged
MH  - Disability Evaluation
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Patient Reported Outcome Measures
MH  - *Quality of Life
MH  - Scoliosis/*surgery
MH  - Self Report
OTO - NOTNLM
OT  - Adult spinal deformity
OT  - COMI
OT  - MCID
OT  - MDC
OT  - ODI
OT  - Outcome
OT  - SF-36
OT  - SRS-22R
OT  - Surgery
EDAT- 2018/07/17 06:00
MHDA- 2020/01/04 06:00
CRDT- 2018/07/17 06:00
PHST- 2018/01/30 00:00 [received]
PHST- 2018/07/04 00:00 [revised]
PHST- 2018/07/05 00:00 [accepted]
PHST- 2018/07/17 06:00 [pubmed]
PHST- 2020/01/04 06:00 [medline]
PHST- 2018/07/17 06:00 [entrez]
AID - S1529-9430(18)30650-8 [pii]
AID - 10.1016/j.spinee.2018.07.005 [doi]
PST - ppublish
SO  - Spine J. 2019 Jan;19(1):71-78. doi: 10.1016/j.spinee.2018.07.005. Epub 2018 Aug 
      27.