PMID- 30015170 OWN - NLM STAT- MEDLINE DCOM- 20180927 LR - 20181004 IS - 1879-2057 (Electronic) IS - 0001-4575 (Linking) VI - 119 DP - 2018 Oct TI - A study on correlation of pedestrian head injuries with physical parameters using in-depth traffic accident data and mathematical models. PG - 91-103 LID - S0001-4575(18)30310-5 [pii] LID - 10.1016/j.aap.2018.07.012 [doi] AB - The objective of the present study is to predict brain injuries and injury severities from realworld traffic accidents via in-depth investigation of head impact responses, injuries and brain injury tolerances. Firstly, a total of 43 passenger car versus adult pedestrian accidents were selected from two databases of the In-depth Investigation of Vehicle Accidents in Changsha of China (IVAC) and the German In-Depth Accident Study (GIDAS). In a previous study the 43 accidents were reconstructed by using the multi-body system (MBS) model (Peng et al., 2013a) for determining the initial conditions of the head-windscreen impact in each accident. Then, a study of the head injuries and injury mechanisms is carried out via 43 finite element (FE) modelings of a head strike to a windscreen, in which the boundary and loading conditions are defined according to results from accident reconstructions, including impact velocity, position and orientation of the head FE model. The brain dynamic responses were calculated for the physical parameters of the coup/countercoup pressure, von Mises and maximum shear stresses at the cerebrum, the callosum, the cerebellum and the brain stem. In addition, head injury criteria, including the cumulative strain damage measure (CSDM) (with tissue level strain threshold 0.20) and the dilatational damage measure (DDM), were developed in order to predict the diffuse axonal injury (DAI) and contusions, respectively. The correlations between calculated parameters and brain injuries were determined via comparing the simulation results with the observed injuries in accident data. The regression models were developed for predicting the injury risks in terms of the brain dynamic responses and the calculated CSDM and DDM values. The results indicate that the predicted values of 50% probability causing head injuries in the Abbreviated Injury Scale (AIS) 2+ correspond to coup pressure 167 kPa, countercoup pressure -117 kPa, von Mises 16.3 kPa and shear stress 7.9 kPa respectively, and causing AIS 3+ head injuries were 227 kPa, -169 kPa, 24.2 kPa and 12.2 kPa respectively. The results also suggest that a 50% probability of contusions corresponds to CSDM value of 48% at strain levels of 0.2, and the 50% probability of contusions corresponds to a DDM value of 6.7%. CI - Copyright (c) 2018 Elsevier Ltd. All rights reserved. FAU - Huang, Jing AU - Huang J AD - Research Center of Vehicle and Traffic Safety (VTS), State Key Laboratory of Advanced Design and Manufacture for Vehicle Body, Hunan University, 410082, China. FAU - Peng, Yong AU - Peng Y AD - Research Center of Vehicle and Traffic Safety (VTS), State Key Laboratory of Advanced Design and Manufacture for Vehicle Body, Hunan University, 410082, China; Key Laboratory of Traffic Safety on Track of Ministry of Education, School of Traffic & Transportation Engineering, Central South University, Changsha, 410075, China. FAU - Yang, Jikuang AU - Yang J AD - Research Center of Vehicle and Traffic Safety (VTS), State Key Laboratory of Advanced Design and Manufacture for Vehicle Body, Hunan University, 410082, China; Department of Applied Mechanics, Chalmers University of Technology, Sweden. Electronic address: jikuangyang@hnu.edu.cn. FAU - Otte, Dietmar AU - Otte D AD - Accident Research Unit, Medical University of Hannover, 30625, Germany. FAU - Wang, Bingyu AU - Wang B AD - Research Center of Vehicle and Traffic Safety (VTS), State Key Laboratory of Advanced Design and Manufacture for Vehicle Body, Hunan University, 410082, China; Xiamen University of Technology, China. LA - eng PT - Journal Article DEP - 20180714 PL - England TA - Accid Anal Prev JT - Accident; analysis and prevention JID - 1254476 SB - IM MH - Abbreviated Injury Scale MH - *Accidents, Traffic MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Brain/*physiology MH - Brain Injuries/*etiology MH - China MH - Contusions/etiology MH - Craniocerebral Trauma/*etiology MH - Diffuse Axonal Injury/etiology MH - Female MH - Humans MH - Male MH - Middle Aged MH - Models, Biological MH - Models, Theoretical MH - *Motor Vehicles MH - *Pedestrians MH - Physical Examination MH - Pressure MH - Stress, Mechanical MH - Young Adult OTO - NOTNLM OT - Brain injury mechanism OT - Human head FE model OT - Pedestrian safety OT - Reconstruction OT - Tolerance threshold OT - Traffic accident EDAT- 2018/07/18 06:00 MHDA- 2018/09/28 06:00 CRDT- 2018/07/18 06:00 PHST- 2018/02/11 00:00 [received] PHST- 2018/07/03 00:00 [revised] PHST- 2018/07/04 00:00 [accepted] PHST- 2018/07/18 06:00 [pubmed] PHST- 2018/09/28 06:00 [medline] PHST- 2018/07/18 06:00 [entrez] AID - S0001-4575(18)30310-5 [pii] AID - 10.1016/j.aap.2018.07.012 [doi] PST - ppublish SO - Accid Anal Prev. 2018 Oct;119:91-103. doi: 10.1016/j.aap.2018.07.012. Epub 2018 Jul 14.