PMID- 30016936
OWN - NLM
STAT- MEDLINE
DCOM- 20190610
LR  - 20190613
IS  - 1471-2261 (Electronic)
IS  - 1471-2261 (Linking)
VI  - 18
IP  - 1
DP  - 2018 Jul 17
TI  - Metabolic syndrome among type 2 diabetic patients in Ethiopia: a cross-sectional 
      study.
PG  - 149
LID - 10.1186/s12872-018-0880-7 [doi]
LID - 149
AB  - BACKGROUND: Metabolic syndrome (MetS) increases risk of cardiovascular diseases 
      (CVD), premature death as well as cost related to health care.This study was 
      aimed at investigating the prevalence of MetS and its determinant factors among 
      type2 diabetes mellitus (T2DM) patients attending a specialized hospital. 
      METHODS: A cross-sectional study was conducted on a total of 256 T2DM patients 
      from the first march to 30th May 2017 at university of gondar comprehensive 
      specialized hospital (UGCSH). Data was collected based on STROBE (strengthening 
      the reporting of observational studies in epidemiology) statement. Bivariable and 
      multivariable logistic regression analysis were run to identify predictors of 
      MetS from the independent variables and significance test was set at P <  0.05. 
      RESULTS: The prevalence of MetS in this study was 70.3, 57 & 45.3% and it is more 
      common in females (66.1, 83.3 & 70.7%) by using national cholesterol education 
      program adult treatment panel III (NCEP-ATP III), International diabetic 
      federation (IDF) and world health organization (WHO) criteria respectively. The 
      most prevalent components of MetS were low level of high density lipoprotein 
      (HDL) and triglyceride(TG). By usingIDF criteria, female gender was significantly 
      associated with MetS (AOR = 0.2 at 95%CI: 0.1, 0.6 P = 0.00). Where as by 
      NCEP-ATP IIIcriteria, age between 51 and 64 years old (AOR = 2.4 95% CI: 1.0,5.8, 
      P = 0.04), self employment (AOR = 2.7 95% CI:1.1, 6.5, P = 0.03), and 
      completetion of secondary school and above (AOR = 3.2, 95% CI:1.6,6.7, P = 0.001) 
      were predictors for the development of MetS. In the WHO criteria, being single in 
      marital status was significantly associated with MetS (AOR = 17 at 95%CI: 1.8, 
      166, P = 0.000). CONCLUSIONS: This study demonstrates that Metabolic syndrome is 
      a major health concern for diabetic patients in Ethiopia and they are at 
      increased risk of developing complications such as cardiovascular diseases and 
      premature mortality. The predictors female gender, age between 51 and 64 years 
      old, urban area residence, and being single are modifiable.Thus,health 
      authorities shall provide targeted interventions such as life style modifications 
      to these most at risk sub-populations of diabetic patients.
FAU - Birarra, Mequanent Kassa
AU  - Birarra MK
AUID- ORCID: 0000-0002-8700-0614
AD  - Department of Clinical Pharmacy, School of Pharmacy,College of Medicine and 
      Health Sciences, University of Gondar, Lideta Street, P.o.box: 196, Gondar, 
      Ethiopia. mekuanentk@gmail.com.
FAU - Gelayee, Dessalegn Asmelashe
AU  - Gelayee DA
AD  - Department of Pharmacology, School of Pharmacy,College of Medicine and Health 
      Sciences, University of Gondar, Gondar, Ethiopia.
LA  - eng
PT  - Journal Article
DEP - 20180717
PL  - England
TA  - BMC Cardiovasc Disord
JT  - BMC cardiovascular disorders
JID - 100968539
SB  - IM
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/diagnosis/*epidemiology
MH  - Ethiopia/epidemiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Metabolic Syndrome/diagnosis/*epidemiology
MH  - Middle Aged
MH  - Prevalence
MH  - Prospective Studies
MH  - Risk Factors
MH  - Sex Factors
MH  - Single Person
MH  - Urban Health
PMC - PMC6050670
OTO - NOTNLM
OT  - Metabolic syndrome
OT  - Type 2 diabetes mellitus
OT  - University of Gondar, Ethiopia
COIS- ETHICS APPROVAL AND CONSENT TO PARTICIPATE: Letter of ethical clearance was 
      obtained from Ethical Review Committee of School of Pharmacy, College of Medicine 
      and Health Sciences University of Gondar, as well as medical director of 
      University of Gondar hospital. Informed verbal consent was obtained from each 
      study participant with respect to their willingness to take part in the study 
      after explaining the objective of the study. This was approved by the Ethical 
      Review Committee of School of Pharmacy, College of Medicine and Health Sciences 
      University of Gondar, as well as medical director of UGCSH. CONSENT FOR 
      PUBLICATION: Not applicable. COMPETING INTERESTS: The authors declare that they 
      have no competing interests. PUBLISHER'S NOTE: Springer Nature remains neutral 
      with regard to jurisdictional claims in published maps and institutional 
      affiliations.
EDAT- 2018/07/19 06:00
MHDA- 2019/06/14 06:00
PMCR- 2018/07/17
CRDT- 2018/07/19 06:00
PHST- 2018/01/08 00:00 [received]
PHST- 2018/07/03 00:00 [accepted]
PHST- 2018/07/19 06:00 [entrez]
PHST- 2018/07/19 06:00 [pubmed]
PHST- 2019/06/14 06:00 [medline]
PHST- 2018/07/17 00:00 [pmc-release]
AID - 10.1186/s12872-018-0880-7 [pii]
AID - 880 [pii]
AID - 10.1186/s12872-018-0880-7 [doi]
PST - epublish
SO  - BMC Cardiovasc Disord. 2018 Jul 17;18(1):149. doi: 10.1186/s12872-018-0880-7.