PMID- 30017270 OWN - NLM STAT- MEDLINE DCOM- 20181029 LR - 20181029 IS - 1872-7727 (Electronic) IS - 0720-048X (Linking) VI - 105 DP - 2018 Aug TI - Cardiac magnetic resonance characteristics in young survivors of aborted sudden cardiac death. PG - 141-147 LID - S0720-048X(18)30209-2 [pii] LID - 10.1016/j.ejrad.2018.06.004 [doi] AB - PURPOSE: We aimed to identify and assess cardiac abnormalities by cardiovascular magnetic resonance (CMR) in a non-ischaemic aborted sudden cardiac death (SCD) population and to establish possible predictors of SCD. METHODS: Thirty-six consecutive SCD survivors [median age 37.6 years (IQR 24.1-43.2), 31% female] with no previous cardiac history or evidence of ischaemic heart disease underwent CMR on day 6 (IQR 4-10) after admission. Data on ventricular volumes and the extent of late gadolinium enhancement (LGE) were collected. Systolic strain analysis was performed using feature tracking software. RESULTS: Left ventricular (LV) and right ventricular (RV) indexed diastolic volumes were 92.9 +/- 28.4 ml/m(2) and 94.1 +/- 29 ml/m(2), respectively. LV ejection fraction (EF) and RV EF were 56.8 +/- 10.7% and 53.7 +/- 10.7%, respectively. Global peak endocardial longitudinal, circumferential, and radial strain were -17.9 +/- 4.28%, -23.2 +/- 5.8%, and 32.8 +/- 10.6%, respectively. Compared to normal range, global longitudinal endocardial strain, longitudinal epicardial strain, circumferential endocardial strain, radial strain, and circumferential endocardial strain rate were impaired. Median volume of LGE was 0.25% (IQR 0.12-1.12) of the LV myocardium with highest prevalence in the inferolateral wall. Patients with cardiomyopathy diagnosis (n = 16) had lower LV strain rate compared to patients without cardiomyopathy (n = 20). CONCLUSIONS: CMR findings in young patients with aborted SCD due to non-ischaemic heart disease seem to be minor. Although only present in small amounts, LGE appears to have a predilection towards the inferolateral wall in this population. CI - Copyright (c) 2018 Elsevier B.V. All rights reserved. FAU - Zaremba, Tomas AU - Zaremba T AD - Department of Cardiology, Aalborg University Hospital, Hobrovej 18-22, DK-9100, Aalborg, Denmark. Electronic address: tz@rn.dk. FAU - Brondberg, Anders Krogh AU - Brondberg AK AD - Department of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, DK-8200, Aarhus N, Denmark. Electronic address: anders.kragh@clin.au.dk. FAU - Jensen, Henrik Kjaerulf AU - Jensen HK AD - Department of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, DK-8200, Aarhus N, Denmark. Electronic address: hkjensen@clin.au.dk. FAU - Kim, Won Yong AU - Kim WY AD - Department of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, DK-8200, Aarhus N, Denmark. Electronic address: yong.kim@clin.au.dk. LA - eng PT - Journal Article DEP - 20180615 PL - Ireland TA - Eur J Radiol JT - European journal of radiology JID - 8106411 RN - 0 (Contrast Media) RN - K2I13DR72L (Gadolinium DTPA) SB - IM MH - Adolescent MH - Adult MH - Cardiomyopathies/pathology MH - Contrast Media MH - Cross-Sectional Studies MH - Death, Sudden, Cardiac/*pathology MH - Female MH - Gadolinium DTPA MH - Heart Ventricles/physiopathology MH - Humans MH - Magnetic Resonance Angiography/methods MH - Magnetic Resonance Imaging, Cine/methods MH - Male MH - Middle Aged MH - Myocardium/pathology MH - Prevalence MH - Prospective Studies MH - Retrospective Studies MH - Survivors MH - Ventricular Function, Left/physiology MH - Ventricular Function, Right/physiology MH - Young Adult OTO - NOTNLM OT - Arrhythmic syndromes OT - CMR OT - Cardiomyopathies OT - Sudden cardiac death OT - Ventricular arrhythmias EDAT- 2018/07/19 06:00 MHDA- 2018/10/30 06:00 CRDT- 2018/07/19 06:00 PHST- 2018/02/18 00:00 [received] PHST- 2018/05/18 00:00 [revised] PHST- 2018/06/04 00:00 [accepted] PHST- 2018/07/19 06:00 [entrez] PHST- 2018/07/19 06:00 [pubmed] PHST- 2018/10/30 06:00 [medline] AID - S0720-048X(18)30209-2 [pii] AID - 10.1016/j.ejrad.2018.06.004 [doi] PST - ppublish SO - Eur J Radiol. 2018 Aug;105:141-147. doi: 10.1016/j.ejrad.2018.06.004. Epub 2018 Jun 15.