PMID- 30018570
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 1664-042X (Print)
IS  - 1664-042X (Electronic)
IS  - 1664-042X (Linking)
VI  - 9
DP  - 2018
TI  - Significant Acute Response of Brain-Derived Neurotrophic Factor Following a 
      Session of Extreme Conditioning Program Is Correlated With Volume of Specific 
      Exercise Training in Trained Men.
PG  - 823
LID - 10.3389/fphys.2018.00823 [doi]
LID - 823
AB  - Several studies have demonstrated an acute and chronic increase of brain-derived 
      neurotrophic factor (BDNF) in relation to different types of physical exercise. 
      Currently, many individuals seek physical training strategies that present 
      different types of stimulation and volume/intensity. Thus, the extreme 
      conditioning methodology has gained great notoriety in the scientific and 
      non-scientific environment. Knowing that BDNF values increase in an 
      effort-dependent manner, it is necessary to study the effects of this strategy on 
      BDNF levels. This study aimed to evaluate the acute response of BDNF in trained 
      men submitted to an extreme conditioning program (ECP) session. Ten volunteers 
      underwent an acute ECP session using the "as many reps as possible" (WOD-AMRAP) 
      method, including three types of exercise (clean, wall ball and double or 
      single-unders) for 9 min. BDNF was measured in the plasma, being collected 
      baseline and immediately after the session. Total load of the clean exercise was 
      five times greater than wall ball exercise (p < 0.05; 2096.1 +/- 387.4 kg vs 415.8 
      +/- 81.03 kg), which influenced little in the total load (p < 0.05, 2511.9 +/- 358.52 
      kg) used. For the total volume, practitioners averaged 1.7 times more repetitions 
      in the wall ball exercise compared to clean (46.2 +/- 9 vs 29.5 +/- 3.8 repetitions). 
      The volunteers averaged 75.7 +/- 12.6 double-unders repetitions, bringing the total 
      volume of training to 151.4 +/- 23.7 repetitions. Regarding the BDNF values, there 
      was a significant difference (p = 0.05) between the pre- vs post-moments 
      (11209.85 +/- 1270.4 vs 12132.96 +/- 1441.93 pg/ml). Effect size for this change as 
      moderate (ES = 0.79). We found a positive correlation between total volume of 
      clean exercise and delta BDNF values (p = 0.049). In conclusion, a single extreme 
      conditioning session, through the practice of the WOD-AMRAP method, is capable of 
      increasing the acute concentrations of plasma BDNF. In practical terms, we may 
      suggest that future studies evaluate the effect of ECP as a strategy in the 
      treatment of disorders associated with central degenerative changes.
FAU - Pereira, Emy S
AU  - Pereira ES
AD  - Laboratory of Morphoquantitative Studies and Immunohistochemistry, Department of 
      Physical Education, Sao Judas Tadeu University, Sao Paulo, Brazil.
AD  - Laboratory of Body Perception and Movement, Department of Physical Education, Sao 
      Judas Tadeu University, Sao Paulo, Brazil.
FAU - Krause Neto, Walter
AU  - Krause Neto W
AD  - Laboratory of Morphoquantitative Studies and Immunohistochemistry, Department of 
      Physical Education, Sao Judas Tadeu University, Sao Paulo, Brazil.
FAU - Calefi, Atilio S
AU  - Calefi AS
AD  - Department of Pathology, Faculty of Veterinary Medicine and Animal Science, 
      University of Sao Paulo, Sao Paulo, Brazil.
FAU - Georgetti, Mariana
AU  - Georgetti M
AD  - Laboratory of Body Perception and Movement, Department of Physical Education, Sao 
      Judas Tadeu University, Sao Paulo, Brazil.
FAU - Guerreiro, Larissa
AU  - Guerreiro L
AD  - Laboratory of Body Perception and Movement, Department of Physical Education, Sao 
      Judas Tadeu University, Sao Paulo, Brazil.
FAU - Zocoler, Cesar A S
AU  - Zocoler CAS
AD  - Laboratory of Human Movement, Department of Physical Education, Sao Judas Tadeu 
      University, Sao Paulo, Brazil.
FAU - Gama, Eliane F
AU  - Gama EF
AD  - Laboratory of Morphoquantitative Studies and Immunohistochemistry, Department of 
      Physical Education, Sao Judas Tadeu University, Sao Paulo, Brazil.
AD  - Laboratory of Body Perception and Movement, Department of Physical Education, Sao 
      Judas Tadeu University, Sao Paulo, Brazil.
LA  - eng
PT  - Journal Article
DEP - 20180703
PL  - Switzerland
TA  - Front Physiol
JT  - Frontiers in physiology
JID - 101549006
EIN - Front Physiol. 2019 Dec 10;10:1492. PMID: 31857806
PMC - PMC6038715
OTO - NOTNLM
OT  - aerobics
OT  - cross training
OT  - effort
OT  - high-intensity interval training
OT  - neurotrophin
OT  - strength training
EDAT- 2018/07/19 06:00
MHDA- 2018/07/19 06:01
PMCR- 2018/07/03
CRDT- 2018/07/19 06:00
PHST- 2018/04/17 00:00 [received]
PHST- 2018/06/12 00:00 [accepted]
PHST- 2018/07/19 06:00 [entrez]
PHST- 2018/07/19 06:00 [pubmed]
PHST- 2018/07/19 06:01 [medline]
PHST- 2018/07/03 00:00 [pmc-release]
AID - 10.3389/fphys.2018.00823 [doi]
PST - epublish
SO  - Front Physiol. 2018 Jul 3;9:823. doi: 10.3389/fphys.2018.00823. eCollection 2018.