PMID- 30022231
OWN - NLM
STAT- MEDLINE
DCOM- 20181120
LR  - 20181120
IS  - 1432-1920 (Electronic)
IS  - 0028-3940 (Linking)
VI  - 60
IP  - 9
DP  - 2018 Sep
TI  - Comparison of field-of-view optimized and constrained undistorted single-shot 
      diffusion-weighted imaging and conventional diffusion-weighted imaging of optic 
      nerve and chiasma at 3T.
PG  - 903-912
LID - 10.1007/s00234-018-2058-5 [doi]
AB  - PURPOSE: Single-shot echo-planar imaging is the conventional diffusion-weighted 
      imaging (C-DWI) sequence for evaluating orbital disease. However, its utility is 
      restricted in small organs like the chiasma and optic nerve. This study was 
      conducted to investigate the utility of field-of-view optimized and constrained 
      undistorted single-shot diffusion-weighted imaging (FOCUS-DWI) for evaluating the 
      chiasma and optic nerve in acute optic neuritis, making comparisons with C-DWI. 
      METHODS: FOCUS-DWI and C-DWI were performed on 36 acute optic neuritis patients 
      and 16 normal controls. Two readers assessed image quality using 5-point Likert 
      scales. Differences in the visual assessments and apparent diffusion coefficient 
      (ADC) values between C-DWI and FOCUS-DWI were evaluated. Inter-observer agreement 
      in the qualitative data was assessed using Cohen's kappa coefficients. Inter- and 
      intra-observer agreements in the ADC values were evaluated using intraclass 
      correlation coefficients. RESULTS: FOCUS-DWI was superior to C-DWI in all aspects 
      of the image evaluations. The Cohen's kappa coefficients for FOCUS-DWI were 
      almost perfect (0.81-1) or substantial (0.61-0.80) for all the image quality 
      categories. In the FOCUS-DWI images, the structural conspicuity of the chiasma 
      and canalicular and cisternal segments was significantly superior on coronal 
      views than on axial views (P < 0.0001). ROC analysis showed that in optic 
      neuritis patients, the diagnostic value of ADC measurements on FOCUS-DWI was 
      higher than ADC values measured on C-DWI. CONCLUSION: The FOCUS-DWI technique can 
      provide substantial improvements over C-DWI for imaging different aspects of the 
      optic nerve and chiasma. The coronal scan direction is more suitable than the 
      axial scan direction for FOCUS-DWI.
FAU - Tian, Yuan
AU  - Tian Y
AD  - Department of Radiology, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 
      China.
AD  - Department of Radiology, 309th Hospital of Chinese People's Liberation Army, 
      Beijing, China.
FAU - Wang, Junqing
AU  - Wang J
AD  - Department of Ophthalmology, Chinese PLA General Hospital, Beijing, China.
FAU - Li, Mingge
AU  - Li M
AD  - Department of Radiology, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 
      China.
FAU - Lou, Xin
AU  - Lou X
AD  - Department of Radiology, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 
      China.
FAU - Tang, Jing
AU  - Tang J
AD  - Department of Radiology, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 
      China.
FAU - Xu, Quangang
AU  - Xu Q
AD  - Department of Ophthalmology, Chinese PLA General Hospital, Beijing, China.
FAU - Zhang, Yingkui
AU  - Zhang Y
AD  - HCS Application-MR, Economic & Technology Development Area, GE Healthcare, 
      Beijing, China.
FAU - Wei, Shihui
AU  - Wei S
AD  - Department of Ophthalmology, Chinese PLA General Hospital, Beijing, China.
FAU - Ma, Lin
AU  - Ma L
AD  - Department of Radiology, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 
      China. cjr.malin@vip.163.com.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20180719
PL  - Germany
TA  - Neuroradiology
JT  - Neuroradiology
JID - 1302751
SB  - IM
MH  - Adult
MH  - Case-Control Studies
MH  - Diffusion Magnetic Resonance Imaging/*methods
MH  - Echo-Planar Imaging/methods
MH  - Female
MH  - Humans
MH  - Male
MH  - Optic Chiasm/*diagnostic imaging
MH  - Optic Nerve/*diagnostic imaging
MH  - Optic Neuritis/*diagnostic imaging
OTO - NOTNLM
OT  - Acute optic neuritis
OT  - Diffusion-weighted imaging
OT  - Magnetic resonance imaging
OT  - Optic nerves
EDAT- 2018/07/20 06:00
MHDA- 2018/11/21 06:00
CRDT- 2018/07/20 06:00
PHST- 2018/04/18 00:00 [received]
PHST- 2018/07/10 00:00 [accepted]
PHST- 2018/07/20 06:00 [pubmed]
PHST- 2018/11/21 06:00 [medline]
PHST- 2018/07/20 06:00 [entrez]
AID - 10.1007/s00234-018-2058-5 [pii]
AID - 10.1007/s00234-018-2058-5 [doi]
PST - ppublish
SO  - Neuroradiology. 2018 Sep;60(9):903-912. doi: 10.1007/s00234-018-2058-5. Epub 2018 
      Jul 19.