PMID- 30023210
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2213-8803 (Electronic)
IS  - 2213-879X (Print)
IS  - 2213-879X (Linking)
VI  - 4
IP  - 2
DP  - 2016 Apr-Jun
TI  - Modulation of dendritic cell immune functions by plant components.
PG  - 55-62
LID - 10.1016/j.jmau.2016.01.001 [doi]
AB  - Dendritic cells (DCs) are the key linkage between innate and adoptive immune 
      response. DCs are classified as specialized antigen-presenting cells that 
      initiate T-cell immune responses during infection and hypersensitivity, and 
      maintain immune tolerance to self-antigens. Initiating T-cell immune responses 
      may be beneficial in infectious diseases or cancer management, while, 
      immunosuppressant or tolerogenic responses could be useful in controlling 
      autoimmunity, allergy or inflammatory diseases. Several types of plant-derived 
      components show promising properties in influencing DC functions. Various types 
      of these components have been proven useful in clinical application and 
      immune-based therapy. Therefore, focusing on the benefits of plant-based medicine 
      regulating DC functions may be useful, low-cost, and accessible strategies for 
      human health. This review illustrates recent studies, investigating the role of 
      plant components in manipulating DC phenotype and function towards 
      immunostimulating or immunosuppressing effects either in vitro or in vivo.
FAU - Aldahlawi, Alia M
AU  - Aldahlawi AM
AD  - Department of Biological Sciences, Faculty of Sciences, King Abdulaziz 
      University, Jeddah, Saudi Arabia.
AD  - Immunology Unit, King Fahd Medical Research Center, King Abdulaziz University, 
      Jeddah, Saudi Arabia.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20160108
PL  - India
TA  - J Microsc Ultrastruct
JT  - Journal of microscopy and ultrastructure
JID - 101709862
PMC - PMC6014213
OTO - NOTNLM
OT  - Dendritic cells
OT  - Herbal medicine
OT  - Immunostimulation
OT  - Immunosuppression
OT  - Plant extract
EDAT- 2016/04/01 00:00
MHDA- 2016/04/01 00:01
PMCR- 2016/04/01
CRDT- 2018/07/20 06:00
PHST- 2015/12/18 00:00 [received]
PHST- 2015/12/24 00:00 [revised]
PHST- 2016/01/01 00:00 [accepted]
PHST- 2018/07/20 06:00 [entrez]
PHST- 2016/04/01 00:00 [pubmed]
PHST- 2016/04/01 00:01 [medline]
PHST- 2016/04/01 00:00 [pmc-release]
AID - JMAU-4-55 [pii]
AID - 10.1016/j.jmau.2016.01.001 [doi]
PST - ppublish
SO  - J Microsc Ultrastruct. 2016 Apr-Jun;4(2):55-62. doi: 10.1016/j.jmau.2016.01.001. 
      Epub 2016 Jan 8.