PMID- 30024818 OWN - NLM STAT- MEDLINE DCOM- 20190314 LR - 20190314 IS - 1532-4109 (Electronic) IS - 0360-1234 (Linking) VI - 53 IP - 10 DP - 2018 TI - National short-term dietary exposure assessment of a selected group of pesticides in Argentina. PG - 639-651 LID - 10.1080/03601234.2018.1474552 [doi] AB - An evaluation of acute dietary exposure to pesticide residues, applying deterministic and stochastic methods, was performed for a selected group of pesticides in two representative age groups from Argentina. Thus, 28 active ingredients (a.i.) and 75 food items were evaluated for the group of 2-5-year-old children, while 9 a.i. and 59 food items were considered for the 10-49-year-old women group. A deterministic assessment was conducting following the Food and Agriculture Organization (FAO) and World Health Organization (WHO) procedure but using the national maximum residue limits (MRLs) as pesticide residue concentration data, while in the stochastic approach, a theoretical distribution modeled with the available information was used. Food consumption data were obtained from the 2004-2005 comprehensive national nutrition and health survey. The risk was estimated by comparing the short-term dietary exposure with the acute reference dose (ARfD) values for each pesticide-food combination evaluated. In the deterministic assessment, 173 (39.1%) and 40 (31.3%) combinations exceeded the ARfD thresholds for the 2-5-year-old children and 10-49-year-old women groups, respectively. This conservative study generated relevant information as a first stage of acute dietary risk assessment in Argentina. FAU - Maggioni, Dario A AU - Maggioni DA AD - a Program of Research and Analysis of Chemical Residues and Contaminants (PRINARC), Faculty of Chemical Engineering , National University of Littoral , Santa Fe , Argentina. FAU - Signorini, Marcelo L AU - Signorini ML AD - b Instituto Nacional de Tecnologia Agropecuaria, EEA Rafaela , Santa Fe , Argentina. FAU - Michlig, Nicolas AU - Michlig N AD - a Program of Research and Analysis of Chemical Residues and Contaminants (PRINARC), Faculty of Chemical Engineering , National University of Littoral , Santa Fe , Argentina. FAU - Repetti, Maria R AU - Repetti MR AD - a Program of Research and Analysis of Chemical Residues and Contaminants (PRINARC), Faculty of Chemical Engineering , National University of Littoral , Santa Fe , Argentina. FAU - Sigrist, Mirna E AU - Sigrist ME AD - a Program of Research and Analysis of Chemical Residues and Contaminants (PRINARC), Faculty of Chemical Engineering , National University of Littoral , Santa Fe , Argentina. FAU - Beldomenico, Horacio R AU - Beldomenico HR AD - a Program of Research and Analysis of Chemical Residues and Contaminants (PRINARC), Faculty of Chemical Engineering , National University of Littoral , Santa Fe , Argentina. LA - eng PT - Comparative Study PT - Journal Article DEP - 20180719 PL - England TA - J Environ Sci Health B JT - Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes JID - 7607167 RN - 0 (Pesticide Residues) SB - IM MH - Adolescent MH - Adult MH - Age Factors MH - Agriculture MH - Argentina MH - Child MH - Child, Preschool MH - Dietary Exposure/*adverse effects/statistics & numerical data MH - Environmental Exposure/statistics & numerical data MH - Environmental Monitoring/statistics & numerical data MH - Female MH - Food Analysis/*statistics & numerical data MH - Food Contamination/*analysis/statistics & numerical data MH - Humans MH - Male MH - Middle Aged MH - Pesticide Residues/*adverse effects/*analysis MH - Reference Values MH - Risk Assessment/*methods/statistics & numerical data MH - Young Adult OTO - NOTNLM OT - ARfD OT - Acute risk assessment OT - dietary exposure OT - pesticide residue OT - stochastic modeling EDAT- 2018/07/20 06:00 MHDA- 2019/03/15 06:00 CRDT- 2018/07/20 06:00 PHST- 2018/07/20 06:00 [pubmed] PHST- 2019/03/15 06:00 [medline] PHST- 2018/07/20 06:00 [entrez] AID - 10.1080/03601234.2018.1474552 [doi] PST - ppublish SO - J Environ Sci Health B. 2018;53(10):639-651. doi: 10.1080/03601234.2018.1474552. Epub 2018 Jul 19.