PMID- 30033310 OWN - NLM STAT- MEDLINE DCOM- 20181106 LR - 20181106 IS - 1873-0191 (Electronic) IS - 0928-4931 (Linking) VI - 91 DP - 2018 Oct 1 TI - Bicomponent fibres for controlled release of volatile mosquito repellents. PG - 754-761 LID - S0928-4931(17)33694-9 [pii] LID - 10.1016/j.msec.2018.06.016 [doi] AB - Core-sheath structured fibres were developed for application as part of an alternative malaria vector control intervention aimed at reducing outdoor malaria transmission. The fibres were prepared by melt spinning of high density polyethylene (HDPE) as sheath and with a concentrate containing volatile N,N-Diethyl-m-toluamide (DEET) in poly(ethylene-co-vinyl acetate) (EVA) as core. The concentrate was prepared by a simple absorption processes to a content up to 40 wt% DEET. Scanning electron microscope imaging confirmed the formation of a bicomponent core-sheath fibre structure. Confocal Raman spectroscopy revealed the development of a concentration gradient of DEET in the sheath layer, suggesting a diffusion controlled release process. Excellent processability was demonstrated on an extrusion system melt spinning with take up speeds reaching 3000 m min(-1). Sample textiles knitted from such filaments showed high residual repellence activity even after 20 cold washes or after eight months ageing under laboratory conditions. These findings indicate that this technology offers an alternative way to prevent outdoor mosquito bites in an effective and affordable manner. CI - Copyright (c) 2018 Elsevier B.V. All rights reserved. FAU - Sibanda, Mthokozisi AU - Sibanda M AD - University of Pretoria Institute for Sustainable Malaria Control and MRC Collaborating Centre for malaria research, University of Pretoria, Private Bag X323, Pretoria 0001, South Africa; Institute of Applied Materials, Department of Chemical Engineering, University of Pretoria, Private Bag X20, Hatfield 0028, South Africa. FAU - Focke, Walter AU - Focke W AD - University of Pretoria Institute for Sustainable Malaria Control and MRC Collaborating Centre for malaria research, University of Pretoria, Private Bag X323, Pretoria 0001, South Africa; Institute of Applied Materials, Department of Chemical Engineering, University of Pretoria, Private Bag X20, Hatfield 0028, South Africa. Electronic address: walter.focke@up.ac.za. FAU - Braack, Leo AU - Braack L AD - University of Pretoria Institute for Sustainable Malaria Control and MRC Collaborating Centre for malaria research, University of Pretoria, Private Bag X323, Pretoria 0001, South Africa. FAU - Leuteritz, Andreas AU - Leuteritz A AD - Leibniz Institute of Polymer Research Dresden (IPF), Hohe Strasse 6, 01069 Dresden, Germany. FAU - Brunig, Harald AU - Brunig H AD - Leibniz Institute of Polymer Research Dresden (IPF), Hohe Strasse 6, 01069 Dresden, Germany. FAU - Tran, Nguyen Hoai An AU - Tran NHA AD - Leibniz Institute of Polymer Research Dresden (IPF), Hohe Strasse 6, 01069 Dresden, Germany; Technische Universitat Dresden, Fakultat Maschinenwesen, Institut fur Textilmaschinen und Textile Hochleistungswerkstofftechnik (ITM), 01062 Dresden, Germany. FAU - Wieczorek, Florian AU - Wieczorek F AD - Technische Universitat Dresden, Fakultat Maschinenwesen, Institut fur Textilmaschinen und Textile Hochleistungswerkstofftechnik (ITM), 01062 Dresden, Germany. FAU - Trumper, Wolfgang AU - Trumper W AD - Technische Universitat Dresden, Fakultat Maschinenwesen, Institut fur Textilmaschinen und Textile Hochleistungswerkstofftechnik (ITM), 01062 Dresden, Germany. LA - eng PT - Journal Article DEP - 20180615 PL - Netherlands TA - Mater Sci Eng C Mater Biol Appl JT - Materials science & engineering. C, Materials for biological applications JID - 101484109 RN - 0 (Delayed-Action Preparations) RN - 0 (Insect Repellents) RN - 134-62-3 (DEET) RN - 9002-88-4 (Polyethylene) SB - IM MH - Animals MH - Culicidae/*drug effects MH - DEET/*toxicity MH - Delayed-Action Preparations MH - Female MH - Imaging, Three-Dimensional MH - Insect Repellents/*toxicity MH - Polyethylene/*chemistry MH - Spectrum Analysis, Raman MH - Stress, Mechanical MH - Textiles MH - Thermogravimetry MH - Volatilization OTO - NOTNLM OT - Bicomponent fibre OT - Controlled release OT - Malaria OT - Mosquitoes OT - Repellent EDAT- 2018/07/24 06:00 MHDA- 2018/11/07 06:00 CRDT- 2018/07/24 06:00 PHST- 2017/09/13 00:00 [received] PHST- 2018/05/11 00:00 [revised] PHST- 2018/06/09 00:00 [accepted] PHST- 2018/07/24 06:00 [entrez] PHST- 2018/07/24 06:00 [pubmed] PHST- 2018/11/07 06:00 [medline] AID - S0928-4931(17)33694-9 [pii] AID - 10.1016/j.msec.2018.06.016 [doi] PST - ppublish SO - Mater Sci Eng C Mater Biol Appl. 2018 Oct 1;91:754-761. doi: 10.1016/j.msec.2018.06.016. Epub 2018 Jun 15.