PMID- 30039284
OWN - NLM
STAT- MEDLINE
DCOM- 20181108
LR  - 20181114
IS  - 1559-1166 (Electronic)
IS  - 0895-8696 (Linking)
VI  - 65
IP  - 4
DP  - 2018 Aug
TI  - Association Between Objectively Measured Physical Activity and Plasma BDNF in 
      Adolescents: DADOS Study.
PG  - 467-471
LID - 10.1007/s12031-018-1122-2 [doi]
AB  - Brain-derived neurotrophic factor (BDNF) is suggested to play a key role in 
      moderating the benefits of physical activity (PA) on cognition. Previous research 
      found that PA may have an impact on peripheral BDNF expression. The aim of our 
      study was to analyze the association between objectively measured PA with 
      circulating BDNF in a group of active adolescents. Two hundred thirty-four 
      adolescents (132 boys) aged 13.9 +/- 0.3 years old from the DADOS study were 
      included in this cross-sectional analysis. PA was assessed by GENEActiv triaxial 
      accelerometer. Participants wore the accelerometer on their non-dominant wrist 
      for 6 consecutive 24-h days, including weekends. PA was expressed as the average 
      (min/day) of light, moderate, and vigorous PA. Fasting plasma BDNF concentrations 
      at rest were measured using an enzyme-linked immunosorbent assay. Partial 
      correlations and linear regression analyses were performed with a significance 
      level established at p < 0.05. No correlations were found between BDNF and PA 
      variables. Plasma levels of BDNF at rest were not significantly associated with 
      daily PA in either boys or girls (p > 0.05). Based on previous research and our 
      own data, the association between daily PA and baseline levels of BDNF remains 
      inconclusive. Further research is needed to shed light on the relationship 
      between regular PA and BDNF in adolescents.
FAU - Beltran-Valls, M R
AU  - Beltran-Valls MR
AD  - LIFE Research Group, University Jaume I, Av. de Vicent Sos Baynat, s/n, 12071, 
      Castellon de la Plana, Castellon, Spain.
AD  - EUSES Health and Sport Sciences School, Rovira i Virgili University, C/ Sebastia 
      Joan Arbo, 2, 43870, Amposta, Tarragona, Spain.
FAU - Adelantado-Renau, M
AU  - Adelantado-Renau M
AD  - LIFE Research Group, University Jaume I, Av. de Vicent Sos Baynat, s/n, 12071, 
      Castellon de la Plana, Castellon, Spain.
FAU - Moliner-Urdiales, D
AU  - Moliner-Urdiales D
AD  - LIFE Research Group, University Jaume I, Av. de Vicent Sos Baynat, s/n, 12071, 
      Castellon de la Plana, Castellon, Spain. dmoliner@uji.es.
LA  - eng
GR  - DEP2013-45515-R/Spanish Ministry of Economy and Competitiveness/
GR  - P1 1A2015-05/University Jaume I of Castellon/
GR  - PREDOC/2015/13/University Jaume I of Castellon/
PT  - Journal Article
DEP - 20180723
PL  - United States
TA  - J Mol Neurosci
JT  - Journal of molecular neuroscience : MN
JID - 9002991
RN  - 0 (Brain-Derived Neurotrophic Factor)
SB  - IM
MH  - Adolescent
MH  - Brain-Derived Neurotrophic Factor/*blood
MH  - Ergometry/methods/standards
MH  - *Exercise
MH  - Humans
MH  - Male
OTO - NOTNLM
OT  - Active behavior
OT  - Adolescence
OT  - Cognition
OT  - Health
OT  - Neurotrophins
EDAT- 2018/07/25 06:00
MHDA- 2018/11/09 06:00
CRDT- 2018/07/25 06:00
PHST- 2018/05/17 00:00 [received]
PHST- 2018/07/11 00:00 [accepted]
PHST- 2018/07/25 06:00 [pubmed]
PHST- 2018/11/09 06:00 [medline]
PHST- 2018/07/25 06:00 [entrez]
AID - 10.1007/s12031-018-1122-2 [pii]
AID - 10.1007/s12031-018-1122-2 [doi]
PST - ppublish
SO  - J Mol Neurosci. 2018 Aug;65(4):467-471. doi: 10.1007/s12031-018-1122-2. Epub 2018 
      Jul 23.