PMID- 30042071 OWN - NLM STAT- MEDLINE DCOM- 20181211 LR - 20181211 IS - 1532-2653 (Electronic) IS - 0967-5868 (Linking) VI - 56 DP - 2018 Oct TI - Sensory phenomena and obsessive-compulsive symptoms in Tourette syndrome following deep brain stimulation: Two case reports. PG - 199-201 LID - S0967-5868(18)30571-X [pii] LID - 10.1016/j.jocn.2018.06.046 [doi] AB - Here, we assess sensory phenomena (SP) and obsessive-compulsive symptoms (OCS) in two patients with refractory Tourette syndrome (TS) before and after deep brain stimulation (DBS) targeting the centromedian-parafascicular complex (CM-Pfc)-ventral oral nuclei of the bilateral thalami. Based on changes in these clinical features, we also aimed to elucidate useful information regarding the use of DBS in TS. We administered the Yale Global Tic Severity Scale (YGTSS) to assess tics, the Premonitory Urge for Tics Scale (PUTS) for premonitory urges, the University of Sao Paulo Sensory Phenomena Scale (USP-SPS) for broader SP, the Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS) for OCS, and the Global Assessment of Functioning (GAF) scale for global functioning. We report on two male patients who showed consistent improvement in tics, premonitory urges, and global functioning two years after DBS. In contrast, there were differences between the patients in broader SP, including "just right" perceptions, and OCS. Our results suggest that systematic assessment of a wide range of SP and OCS dimensions is necessary to elucidate the usefulness of DBS in TS. CI - Copyright (c) 2018 Elsevier Ltd. All rights reserved. FAU - Kano, Yukiko AU - Kano Y AD - Department of Child Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bukyo-ku, Tokyo 113-8655, Japan; Department of Child Psychiatry, The University of Tokyo Hospital, 7-3-1 Hongo, Bukyo-ku, Tokyo 113-8655, Japan. Electronic address: kano-tky@umin.ac.jp. FAU - Matsuda, Natsumi AU - Matsuda N AD - Department of Child Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bukyo-ku, Tokyo 113-8655, Japan; Department of Child Psychiatry, The University of Tokyo Hospital, 7-3-1 Hongo, Bukyo-ku, Tokyo 113-8655, Japan. FAU - Nonaka, Maiko AU - Nonaka M AD - Course of Clinical Psychology, Graduate School of Education, The University of Tokyo, 7-3-1 Hongo, Bukyo-ku, Tokyo 113-0033, Japan. FAU - Fujio, Miyuki AU - Fujio M AD - Department of Child Psychiatry, The University of Tokyo Hospital, 7-3-1 Hongo, Bukyo-ku, Tokyo 113-8655, Japan. FAU - Kono, Toshiaki AU - Kono T AD - Department of Child Psychiatry, The University of Tokyo Hospital, 7-3-1 Hongo, Bukyo-ku, Tokyo 113-8655, Japan; Department of Forensic Psychiatry, National Institute of Mental Health, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi-cho, Kodaira-shi, Tokyo 187-8553, Japan. FAU - Kaido, Takanobu AU - Kaido T AD - Department of Neurosurgery, National Center Hospital, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi-cho, Kodaira-shi, Tokyo 187-8551, Japan. LA - eng PT - Case Reports PT - Journal Article DEP - 20180702 PL - Scotland TA - J Clin Neurosci JT - Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia JID - 9433352 SB - IM MH - Adult MH - Deep Brain Stimulation/*adverse effects MH - Humans MH - Male MH - Middle Aged MH - Obsessive-Compulsive Disorder/*etiology MH - *Sensation MH - Tourette Syndrome/*therapy OTO - NOTNLM OT - Deep brain stimulation OT - Obsessive-compulsive symptoms OT - Refractory Tourette syndrome OT - Sensory phenomena OT - Tics EDAT- 2018/07/26 06:00 MHDA- 2018/12/12 06:00 CRDT- 2018/07/26 06:00 PHST- 2018/03/31 00:00 [received] PHST- 2018/06/25 00:00 [accepted] PHST- 2018/07/26 06:00 [pubmed] PHST- 2018/12/12 06:00 [medline] PHST- 2018/07/26 06:00 [entrez] AID - S0967-5868(18)30571-X [pii] AID - 10.1016/j.jocn.2018.06.046 [doi] PST - ppublish SO - J Clin Neurosci. 2018 Oct;56:199-201. doi: 10.1016/j.jocn.2018.06.046. Epub 2018 Jul 2.