PMID- 300438 OWN - NLM STAT- MEDLINE DCOM- 19770520 LR - 20161017 IS - 0098-7484 (Print) IS - 0098-7484 (Linking) VI - 237 IP - 15 DP - 1977 Apr 11 TI - Isolated aortic valve replacement in patients older than 65 years. PG - 1578-81 AB - The results of 196 isolated aortic valve replacements in patients older than 65 years were analyzed. Eighty-four percent of patients were in New York Heart Association (NYHA) functional class III or IV preoperatively. The operative mortality was 12% for all cases and 9% for elective cases. Actuarial probability of five-year survival was 55% for the entire group and 61% for discharged patients. Myocardial failure and congestive heart failure were the most common causes of early and late postoperative death, respectively. Embolic strokes occurred in 16% of discharged patients and caused substantial disability in 9%. At the termination of the study, 94% of surviving patients were in NYHA class I or II, and none were in class IV. Aortic valve replacement in elderly patients entails reasonable operative risk, and results in satisfactory postoperative rehabilitation. FAU - Copeland, J G AU - Copeland JG FAU - Griepp, R B AU - Griepp RB FAU - Stinson, E B AU - Stinson EB FAU - Shumway, N E AU - Shumway NE LA - eng PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - JAMA JT - JAMA JID - 7501160 SB - IM MH - Age Factors MH - Aged MH - Angiography MH - Aortic Valve/*surgery MH - Aortic Valve Insufficiency/surgery MH - Aortic Valve Stenosis/surgery MH - Arrhythmias, Cardiac/etiology MH - Cardiac Surgical Procedures/mortality MH - Coronary Artery Bypass MH - Coronary Circulation MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Postoperative Complications MH - Preoperative Care MH - Time Factors EDAT- 1977/04/11 00:00 MHDA- 1977/04/11 00:01 CRDT- 1977/04/11 00:00 PHST- 1977/04/11 00:00 [pubmed] PHST- 1977/04/11 00:01 [medline] PHST- 1977/04/11 00:00 [entrez] PST - ppublish SO - JAMA. 1977 Apr 11;237(15):1578-81.