PMID- 30046617
OWN - NLM
STAT- MEDLINE
DCOM- 20181105
LR  - 20181114
IS  - 2314-7156 (Electronic)
IS  - 2314-8861 (Print)
IS  - 2314-7156 (Linking)
VI  - 2018
DP  - 2018
TI  - Strength Training Session Induces Important Changes on Physiological, 
      Immunological, and Inflammatory Biomarkers.
PG  - 9675216
LID - 10.1155/2018/9675216 [doi]
LID - 9675216
AB  - Strength exercise is a strategy applied in sports and physical training 
      processes. It may induce skeletal muscle hypertrophy. The hypertrophy is 
      dependent on the eccentric muscle actions and on the inflammatory response. Here, 
      we evaluate the physiological, immunological, and inflammatory responses induced 
      by a session of strength training with a focus on predominance of the eccentric 
      muscle actions. Twenty volunteers were separated into two groups: the untrained 
      group (UTG) and the trained group (TG). Both groups hold 4 sets of leg press, 
      knee extensor, and leg curl at 65% of personal one-repetition maximum (1RM), 90 s 
      of recovery, and 2('')conc/3('')eccen of duration of execution in each repetition. 
      Blood samples were collected immediately before and after, 2 hours after, and 
      24 h after the end of the exercise session. The single session of strength 
      training elevated the heart rate (HR), rating of perceived exertion (RPE), visual 
      analog scale (VAS), and lactate blood level in UTG and TG. Creatine kinase (CK) 
      levels were higher at 2 and 24 h after the end of the exercise in UTG and, in TG, 
      only at 24 h. The number of white blood cells (WBC) and neutrophils increased in 
      UTG and TG, post and 2 h after exercise. Lymphocytes increased postexercise but 
      reduced 2 h after exercise in both groups, while the number of monocytes 
      increased only immediately after the exercise session in UTG and TG. The strength 
      training session elevated the levels of apelin and fatty acid-binding proteins-3 
      (FABP3) in both groups and brain-derived neurotrophic factor (BDNF) in TG. The 
      single exercise session was capable of inducing elevated HR, RPE, lactate level, 
      and CK levels. This protocol changed the count/total number of circulating immune 
      cells in both groups (UTG and TG) and also increased the level of plasmatic 
      apelin, BDNF, and FLTS1 only in TG and FABP3 myokines in both groups.
FAU - Fortunato, Ayla Karine
AU  - Fortunato AK
AD  - Laboratorio de Inflamacao e Imunologia do Exercicio (LABIIEX), Centro Desportivo 
      da Universidade Federal de Ouro Preto (CEDUFOP/UFOP), Ouro Preto, MG, Brazil.
AD  - Laboratorio da Imunobiologia da Inflamacao (LABIIN/ICEB), Instituto de Ciencia 
      Exatas e Biologicas (ICEB/UFOP), Ouro Preto, MG, Brazil.
FAU - Pontes, Washington Martins
AU  - Pontes WM
AD  - Laboratorio de Inflamacao e Imunologia do Exercicio (LABIIEX), Centro Desportivo 
      da Universidade Federal de Ouro Preto (CEDUFOP/UFOP), Ouro Preto, MG, Brazil.
AD  - Laboratorio da Imunobiologia da Inflamacao (LABIIN/ICEB), Instituto de Ciencia 
      Exatas e Biologicas (ICEB/UFOP), Ouro Preto, MG, Brazil.
FAU - De Souza, Debora Maria Soares
AU  - De Souza DMS
AD  - Laboratorio da Imunobiologia da Inflamacao (LABIIN/ICEB), Instituto de Ciencia 
      Exatas e Biologicas (ICEB/UFOP), Ouro Preto, MG, Brazil.
FAU - Prazeres, Jessica Santos Ferreira
AU  - Prazeres JSF
AD  - Laboratorio de Inflamacao e Imunologia do Exercicio (LABIIEX), Centro Desportivo 
      da Universidade Federal de Ouro Preto (CEDUFOP/UFOP), Ouro Preto, MG, Brazil.
AD  - Laboratorio da Imunobiologia da Inflamacao (LABIIN/ICEB), Instituto de Ciencia 
      Exatas e Biologicas (ICEB/UFOP), Ouro Preto, MG, Brazil.
FAU - Marcucci-Barbosa, Lucas Soares
AU  - Marcucci-Barbosa LS
AD  - Laboratorio de Inflamacao e Imunologia do Exercicio (LABIIEX), Centro Desportivo 
      da Universidade Federal de Ouro Preto (CEDUFOP/UFOP), Ouro Preto, MG, Brazil.
FAU - Santos, Julia Miranda Mol
AU  - Santos JMM
AD  - Laboratorio de Inflamacao e Imunologia do Exercicio (LABIIEX), Centro Desportivo 
      da Universidade Federal de Ouro Preto (CEDUFOP/UFOP), Ouro Preto, MG, Brazil.
FAU - Veira, Erica Leandro Marciano
AU  - Veira ELM
AUID- ORCID: 0000-0002-4147-5614
AD  - Laboratorio Interdisciplinar de Investigacao Medica (LIIM), Faculdade de Medicina 
      (UFMG), Belo Horizonte, MG, Brazil.
FAU - Bearzoti, Eduardo
AU  - Bearzoti E
AD  - Departamento de Estatistica, Universidade Federal de Ouro Preto (UFOP), Ouro 
      Preto, MG, Brazil.
FAU - Pinto, Kelerson Mauro De Castro
AU  - Pinto KMC
AD  - Laboratorio de Inflamacao e Imunologia do Exercicio (LABIIEX), Centro Desportivo 
      da Universidade Federal de Ouro Preto (CEDUFOP/UFOP), Ouro Preto, MG, Brazil.
AD  - Laboratorio da Imunobiologia da Inflamacao (LABIIN/ICEB), Instituto de Ciencia 
      Exatas e Biologicas (ICEB/UFOP), Ouro Preto, MG, Brazil.
FAU - Talvani, Andre
AU  - Talvani A
AUID- ORCID: 0000-0002-6685-6229
AD  - Laboratorio da Imunobiologia da Inflamacao (LABIIN/ICEB), Instituto de Ciencia 
      Exatas e Biologicas (ICEB/UFOP), Ouro Preto, MG, Brazil.
FAU - Da Silva, Albena Nunes
AU  - Da Silva AN
AUID- ORCID: 0000-0002-5236-3124
AD  - Laboratorio de Inflamacao e Imunologia do Exercicio (LABIIEX), Centro Desportivo 
      da Universidade Federal de Ouro Preto (CEDUFOP/UFOP), Ouro Preto, MG, Brazil.
AD  - Laboratorio da Imunobiologia da Inflamacao (LABIIN/ICEB), Instituto de Ciencia 
      Exatas e Biologicas (ICEB/UFOP), Ouro Preto, MG, Brazil.
LA  - eng
PT  - Journal Article
DEP - 20180626
PL  - Egypt
TA  - J Immunol Res
JT  - Journal of immunology research
JID - 101627166
RN  - 0 (Apelin)
RN  - 0 (Biomarkers)
RN  - 0 (Brain-Derived Neurotrophic Factor)
RN  - 0 (FABP3 protein, human)
RN  - 0 (Fatty Acid Binding Protein 3)
RN  - 33X04XA5AT (Lactic Acid)
RN  - EC 2.7.3.2 (Creatine Kinase)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Apelin/blood
MH  - Biomarkers/metabolism
MH  - Brain-Derived Neurotrophic Factor/metabolism
MH  - Creatine Kinase/blood
MH  - Exercise/*physiology
MH  - Fatty Acid Binding Protein 3/metabolism
MH  - Heart Rate
MH  - Humans
MH  - Hypertrophy
MH  - Lactic Acid/blood
MH  - Lymphocytes/*pathology
MH  - Male
MH  - Muscle, Skeletal/metabolism/*pathology
MH  - Teaching
MH  - Visual Analog Scale
MH  - Young Adult
PMC - PMC6038656
EDAT- 2018/07/27 06:00
MHDA- 2018/11/06 06:00
PMCR- 2018/06/26
CRDT- 2018/07/27 06:00
PHST- 2018/02/08 00:00 [received]
PHST- 2018/03/30 00:00 [revised]
PHST- 2018/04/18 00:00 [accepted]
PHST- 2018/07/27 06:00 [entrez]
PHST- 2018/07/27 06:00 [pubmed]
PHST- 2018/11/06 06:00 [medline]
PHST- 2018/06/26 00:00 [pmc-release]
AID - 10.1155/2018/9675216 [doi]
PST - epublish
SO  - J Immunol Res. 2018 Jun 26;2018:9675216. doi: 10.1155/2018/9675216. eCollection 
      2018.