PMID- 30048903
OWN - NLM
STAT- MEDLINE
DCOM- 20181112
LR  - 20181112
IS  - 1873-4367 (Electronic)
IS  - 0927-7765 (Linking)
VI  - 171
DP  - 2018 Nov 1
TI  - Mathematical models and fractal analysis for the investigation of the 
      photodynamic inactivation in phytopathogenic microorganisms.
PG  - 285-290
LID - S0927-7765(18)30466-1 [pii]
LID - 10.1016/j.colsurfb.2018.07.019 [doi]
AB  - The increasing and indiscriminate use of pesticides may lead to the intoxication 
      and contamination of the environment and foods. In addition, pesticides can cause 
      fungal resistance promoting the selection of resistant phytopathogenic fungi. 
      This is a problem in the agricultural and human health areas, which leads to a 
      need for developing new methodologies to address this problem. Photodynamic 
      inactivation is a promising strategy involving the association of a 
      photosensitizer (PS), light, and molecular oxygen to inhibit the growth of 
      microorganisms. In this work, the PS acridine orange (AO) was deposited using the 
      spray layer-by-layer technique. The effectiveness of the method was evaluated by 
      the analysis of the growth evolution of the colonies as a function of the amount 
      of PS layers applied in field in the presence of sunlight. Image processing and 
      analysis of the fractal theory were used to evaluate the growth of the colonies. 
      The results revealed that AO is a candidate PS for use in field. It was possible 
      to observe the reduction of the growth dynamics of the colonies with the increase 
      of the number of PS layers. The parameters related to the fractality of the 
      system were described by mathematical models of the fractal growth of interfaces. 
      The knowledge of these parameters can help to identify new strategies for the 
      control of phytopathogenic microorganisms that directly affect agricultural 
      production.
CI  - Copyright (c) 2018 Elsevier B.V. All rights reserved.
FAU - Kalck, Alessandro S
AU  - Kalck AS
AD  - Grupo de Materiais Nanoestruturados, Universidade Federal de Mato Grosso, Barra 
      do Garcas, Mato Grosso, Brazil.
FAU - Pedro, Maria F Costa
AU  - Pedro MFC
AD  - Grupo de Materiais Nanoestruturados, Universidade Federal de Mato Grosso, Barra 
      do Garcas, Mato Grosso, Brazil.
FAU - Dos Santos, Kevin F
AU  - Dos Santos KF
AD  - Grupo de Materiais Nanoestruturados, Universidade Federal de Mato Grosso, Barra 
      do Garcas, Mato Grosso, Brazil.
FAU - Sousa, Marcos S
AU  - Sousa MS
AD  - Grupo de Materiais Nanoestruturados, Universidade Federal de Mato Grosso, Barra 
      do Garcas, Mato Grosso, Brazil.
FAU - Silva, Josmary R
AU  - Silva JR
AD  - Grupo de Materiais Nanoestruturados, Universidade Federal de Mato Grosso, Barra 
      do Garcas, Mato Grosso, Brazil.
FAU - de Souza, Nara C
AU  - de Souza NC
AD  - Grupo de Materiais Nanoestruturados, Universidade Federal de Mato Grosso, Barra 
      do Garcas, Mato Grosso, Brazil. Electronic address: ncsouza@ufmt.br.
LA  - eng
PT  - Journal Article
DEP - 20180710
PL  - Netherlands
TA  - Colloids Surf B Biointerfaces
JT  - Colloids and surfaces. B, Biointerfaces
JID - 9315133
RN  - 0 (Antifungal Agents)
RN  - 0 (Photosensitizing Agents)
RN  - F30N4O6XVV (Acridine Orange)
SB  - IM
MH  - Acridine Orange/chemistry/*pharmacology
MH  - Antifungal Agents/chemistry/*pharmacology
MH  - *Fractals
MH  - Fungi/*drug effects/growth & development
MH  - Humans
MH  - Microbial Sensitivity Tests
MH  - *Models, Biological
MH  - *Photochemotherapy
MH  - Photosensitizing Agents/chemistry/*pharmacology
MH  - Sunlight
OTO - NOTNLM
OT  - Acridine orange
OT  - Growth rate
OT  - Image processing
OT  - UV radiation
EDAT- 2018/07/27 06:00
MHDA- 2018/11/13 06:00
CRDT- 2018/07/27 06:00
PHST- 2018/05/03 00:00 [received]
PHST- 2018/06/15 00:00 [revised]
PHST- 2018/07/09 00:00 [accepted]
PHST- 2018/07/27 06:00 [pubmed]
PHST- 2018/11/13 06:00 [medline]
PHST- 2018/07/27 06:00 [entrez]
AID - S0927-7765(18)30466-1 [pii]
AID - 10.1016/j.colsurfb.2018.07.019 [doi]
PST - ppublish
SO  - Colloids Surf B Biointerfaces. 2018 Nov 1;171:285-290. doi: 
      10.1016/j.colsurfb.2018.07.019. Epub 2018 Jul 10.