PMID- 30062367
OWN - NLM
STAT- MEDLINE
DCOM- 20191025
LR  - 20191025
IS  - 1120-9135 (Print)
IS  - 1120-9135 (Linking)
VI  - 30
IP  - 5
DP  - 2018 Sep-Oct
TI  - Epidemiology of toxic shock syndrome toxin-1 harboring Staphylococcus aureus 
      obtained from clinical samples in Iran: A Systematic Review and Meta-analysis.
PG  - 391-400
LID - 10.7416/ai.2018.2239 [doi]
AB  - BACKGROUND: S. aureus strains, with the capability of producing toxic shock 
      syndrome toxin-1 (TSST-1), are more likely to cause complicated infections. 
      However, due to lack of comprehensive local data on the prevalence of TSST-1, we 
      aimed to determine the prevalence of TSST-1 harboring S. aureus isolates in Iran. 
      METHODS: A systematic search was performed by using PubMed and Scopus databases 
      from papers published by Iranian authors from January 2000 to the end of March 
      2017. Then, 10 publications which were matched with inclusion criteria were 
      selected for data extraction and analysis by Comprehensive Meta-Analysis 
      Software. RESULTS: The overall prevalence of TSST-1 carrying S. aureus in Iran 
      was 21.3% (95% CI: 7.9%-46.1%), ranging from 0% to 68%. Moreover, from the 
      included studies, the pooled prevalence of TSST-1 producing MRSA isolates was 
      estimated to be 25.2% (95% CI: 13.3%-42.5%), ranging from 0% to 69.8%. From those 
      studies which showed the distribution of toxin-harboring S. aureus it was found 
      that the skin and soft tissue, respiratory and bloodstream infections were the 
      common sites of TSST-1 harboring S. aureus. CONCLUSIONS: In summary, it seems 
      that emergence of MRSA strains leads to higher prevalence of TSST-1 carrying 
      strains in the north of Iran. However, further research is required to elucidate 
      the interplay between the outcome of diseases and TSST-1 producing strains, 
      especially in our country.
FAU - Shahini Shams-Abadi, M
AU  - Shahini Shams-Abadi M
AD  - Department of Bacteriology and Virology, School of Medicine, Shiraz University of 
      Medical Sciences, Shiraz, Iran.
FAU - Halaji, M
AU  - Halaji M
AD  - Department of Microbiology, School of Medicine, Isfahan University of Medical 
      Sciences, Isfahan, Iran.
FAU - Hoseini-Alfatemi, S M
AU  - Hoseini-Alfatemi SM
AD  - Pediatric Infections Research Center, Research institute for Children Health, 
      Shahid Beheshti University of Medical Sciences, Tehran, Iran.
FAU - Gholipour, A
AU  - Gholipour A
AD  - Department of Microbiology and Immunology, Cellular and Molecular Research 
      Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.
FAU - Mojtahedi, A
AU  - Mojtahedi A
AD  - Department of Microbiology, Faculty of Medicine, Guilan University of Medical 
      Sciences, Rasht, Iran.
FAU - Sedigh Ebrahim-Saraie, H
AU  - Sedigh Ebrahim-Saraie H
AD  - Department of Bacteriology and Virology, School of Medicine, Shiraz University of 
      Medical Sciences, Shiraz, Iran.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Systematic Review
PL  - Italy
TA  - Ann Ig
JT  - Annali di igiene : medicina preventiva e di comunita
JID - 9002865
RN  - 0 (Bacterial Toxins)
RN  - 0 (Enterotoxins)
RN  - 0 (Superantigens)
RN  - 0 (enterotoxin F, Staphylococcal)
SB  - IM
MH  - Bacteremia/epidemiology/microbiology
MH  - Bacterial Toxins/biosynthesis
MH  - Enterotoxins/biosynthesis
MH  - Humans
MH  - Iran/epidemiology
MH  - Prevalence
MH  - Respiratory Tract Infections/epidemiology/microbiology
MH  - Skin Diseases, Bacterial/epidemiology/microbiology
MH  - Staphylococcal Infections/*epidemiology/microbiology
MH  - Staphylococcus aureus/*isolation & purification
MH  - Superantigens/biosynthesis
OTO - NOTNLM
OT  - Iran
OT  - MRSA
OT  - Meta-analysis
OT  - Staphylococcus aureus
OT  - TSST-1
EDAT- 2018/08/01 06:00
MHDA- 2019/10/28 06:00
CRDT- 2018/08/01 06:00
PHST- 2018/08/01 06:00 [entrez]
PHST- 2018/08/01 06:00 [pubmed]
PHST- 2019/10/28 06:00 [medline]
AID - 10.7416/ai.2018.2239 [doi]
PST - ppublish
SO  - Ann Ig. 2018 Sep-Oct;30(5):391-400. doi: 10.7416/ai.2018.2239.