PMID- 30063442
OWN - NLM
STAT- MEDLINE
DCOM- 20190920
LR  - 20190920
IS  - 1744-8417 (Electronic)
IS  - 1744-6651 (Linking)
VI  - 13
IP  - 1
DP  - 2018 Jan
TI  - Exercise-induced myokines: a brief review of controversial issues of this decade.
PG  - 51-58
LID - 10.1080/17446651.2018.1416290 [doi]
AB  - INTRODUCTION: Myokines, known to mediate metabolism, inflammation, and other 
      pathophysiological conditions, have been widely investigated, including myokines 
      induced by exercise. However, among published literature, there is substantial 
      inconsistency in the quantification of exercise-induced myokines. Here, we 
      summarized and compared published data regarding the effects of exercise on 
      commonly studied myokines including apelin, Brain-derived neurotrophic factor 
      (BDNF), Interleukin-15 (IL-15), irisin, and Secreted protein acidic and rich in 
      cysteine (SPARC) during the last decade and discussed possible reasons for 
      discrepancy in these reports. AREAS COVERED: A search on PubMed for original 
      articles published in this decade was conducted, focusing on the impacts of 
      exercises on myokines and metabolic and age-related disorders. Beneficial 
      relationship between skeletal muscle plasticity and myokines due to exercise is 
      also discussed. EXPERT COMMENTARY: Based on these analyses, exercise induces the 
      secretion of a number of myokines, which has positive effects on metabolic 
      diseases or age-related muscle atrophy (sarcopenia). However, among published 
      reports, there is wide discrepancy in the quantification of myokines induced by 
      exercise, which could be due to timing of sample collection, pre-analytic sample 
      processing, analytical method, and calculation and other factors. Thus, these 
      factors need to be considered in future studies on exercise induced myokines.
FAU - Son, Jun Seok
AU  - Son JS
AD  - a Nutrigenomics and Growth Biology Laboratory, Department of Animal Sciences , 
      Washington State University , Pullman , WA , USA.
FAU - Chae, Song Ah
AU  - Chae SA
AD  - b Department of Movement Sciences , University of Idaho , Moscow , ID , USA.
FAU - Testroet, Eric D
AU  - Testroet ED
AD  - a Nutrigenomics and Growth Biology Laboratory, Department of Animal Sciences , 
      Washington State University , Pullman , WA , USA.
FAU - Du, Min
AU  - Du M
AD  - a Nutrigenomics and Growth Biology Laboratory, Department of Animal Sciences , 
      Washington State University , Pullman , WA , USA.
FAU - Jun, Hyung-Pil
AU  - Jun HP
AD  - b Department of Movement Sciences , University of Idaho , Moscow , ID , USA.
AD  - c Yonsei Institute of Sport Science and Exercise Medicine , Seoul , South Korea.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20171219
PL  - England
TA  - Expert Rev Endocrinol Metab
JT  - Expert review of endocrinology & metabolism
JID - 101278293
RN  - 0 (Cytokines)
SB  - IM
MH  - Cytokines/*metabolism/physiology
MH  - Exercise/*physiology
MH  - Exercise Therapy
MH  - Health Status
MH  - Humans
MH  - Muscle, Skeletal/metabolism
OTO - NOTNLM
OT  - Exercise
OT  - atrophy
OT  - metabolic disease
OT  - myokine
OT  - sarcopenia
OT  - skeletal muscle
EDAT- 2018/08/01 06:00
MHDA- 2019/09/21 06:00
CRDT- 2018/08/01 06:00
PHST- 2018/08/01 06:00 [entrez]
PHST- 2018/08/01 06:00 [pubmed]
PHST- 2019/09/21 06:00 [medline]
AID - 10.1080/17446651.2018.1416290 [doi]
PST - ppublish
SO  - Expert Rev Endocrinol Metab. 2018 Jan;13(1):51-58. doi: 
      10.1080/17446651.2018.1416290. Epub 2017 Dec 19.