PMID- 30078744
OWN - NLM
STAT- MEDLINE
DCOM- 20191209
LR  - 20191217
IS  - 1885-5857 (Electronic)
IS  - 1885-5857 (Linking)
VI  - 72
IP  - 8
DP  - 2019 Aug
TI  - Prognostic Value of the Nutritional Risk Index in Candidates for Continuous Flow 
      Left Ventricular Assist Device Therapy.
PG  - 608-615
LID - S1885-5857(18)30297-4 [pii]
LID - 10.1016/j.rec.2018.05.029 [doi]
AB  - INTRODUCTION AND OBJECTIVES: Malnutrition has been shown to affect clinical 
      outcomes in patients with heart failure. The aim of this study was to analyze the 
      impact of preoperative nutritional status assessed by the nutritional risk index 
      (NRI) on the prognosis of patients with a continuous-flow left ventricular assist 
      device (cf-LVAD). METHODS: We performed a retrospective study of 279 patients who 
      underwent cf-LVAD implantation between 2009 and 2015 in our center. Preoperative 
      NRI was calculated and the patients were followed-up for 1 year. The association 
      between preoperative NRI and postoperative clinical events was analyzed using 
      multivariable logistic regression. RESULTS: The prevalence of severe (NRI <83.5), 
      moderate (83.5 </= NRI <97.5) and mild (97.5 </= NRI <100) nutritional risk was 5.4%, 
      21.5%, and 9.3%. Mortality rates 1 year after cf-LVAD implantation in these 3 
      categories were 53.3%, 31.7%, 23.1% vs 18.0% (P <.001) in patients with a normal 
      IRN. A normal preoperative NRI value was an independent predictor of lower risk 
      of death from any cause during follow-up (aHR per 1 unit, 0.961; 95%CI, 
      0.941-0.981; P <.001) was and a predictor for a lower risk of postoperative 
      infections (aOR, 0.968; 95%CI, 0.946-0.991; P=.007), respiratory failure (aOR, 
      0,961; 95%CI, 0.936-0.987; P=.004), and right heart failure (aOR, 0.963; 95%CI, 
      0.934-0.992; P=.014). CONCLUSIONS: Malnourished patients are at increased risk 
      for postoperative complications and death after cf-LVAD implantation. Assessment 
      of nutritional risk could improve patient selection and the early initiation of 
      nutritional support.
CI  - Copyright (c) 2018 Sociedad Espanola de Cardiologia. Published by Elsevier Espana, 
      S.L.U. All rights reserved.
FAU - Uribarri, Aitor
AU  - Uribarri A
AD  - Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover 
      Medical School, Hannover, Germany. Electronic address: auribarrig@gmail.com.
FAU - Rojas, Sebastian V
AU  - Rojas SV
AD  - Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover 
      Medical School, Hannover, Germany.
FAU - Hanke, Jasmin S
AU  - Hanke JS
AD  - Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover 
      Medical School, Hannover, Germany.
FAU - Dogan, Gunes
AU  - Dogan G
AD  - Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover 
      Medical School, Hannover, Germany.
FAU - Siemeni, Thierry
AU  - Siemeni T
AD  - Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover 
      Medical School, Hannover, Germany.
FAU - Kaufeld, Tim
AU  - Kaufeld T
AD  - Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover 
      Medical School, Hannover, Germany.
FAU - Ius, Fabio
AU  - Ius F
AD  - Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover 
      Medical School, Hannover, Germany.
FAU - Goecke, Tobias
AU  - Goecke T
AD  - Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover 
      Medical School, Hannover, Germany.
FAU - Rojas-Hernandez, Sara
AU  - Rojas-Hernandez S
AD  - Department of Anaesthesiology, Hannover Medical School, Hannover, Germany.
FAU - Warnecke, Gregor
AU  - Warnecke G
AD  - Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover 
      Medical School, Hannover, Germany.
FAU - Bara, Christoph
AU  - Bara C
AD  - Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover 
      Medical School, Hannover, Germany.
FAU - Avsar, Murat
AU  - Avsar M
AD  - Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover 
      Medical School, Hannover, Germany.
FAU - Haverich, Axel
AU  - Haverich A
AD  - Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover 
      Medical School, Hannover, Germany.
LA  - eng
LA  - spa
PT  - Journal Article
DEP - 20180802
PL  - Spain
TA  - Rev Esp Cardiol (Engl Ed)
JT  - Revista espanola de cardiologia (English ed.)
JID - 101587954
SB  - IM
MH  - Body Weight
MH  - Female
MH  - Follow-Up Studies
MH  - Germany/epidemiology
MH  - Heart Failure/complications/*surgery
MH  - *Heart-Assist Devices
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Malnutrition/diagnosis/epidemiology/*etiology
MH  - Middle Aged
MH  - *Nutritional Status
MH  - *Patient Selection
MH  - Preoperative Period
MH  - Prognosis
MH  - Retrospective Studies
MH  - Risk Assessment/*methods
MH  - Risk Factors
MH  - Time Factors
OTO - NOTNLM
OT  - Desnutricion
OT  - Dispositivo de asistencia ventricular
OT  - Malnourishment
OT  - Nutritional risk index
OT  - Outcomes
OT  - Pronostico
OT  - Ventricular assist device
OT  - Indice de riesgo nutricional
EDAT- 2018/08/07 06:00
MHDA- 2019/12/18 06:00
CRDT- 2018/08/07 06:00
PHST- 2018/03/16 00:00 [received]
PHST- 2018/05/23 00:00 [accepted]
PHST- 2018/08/07 06:00 [pubmed]
PHST- 2019/12/18 06:00 [medline]
PHST- 2018/08/07 06:00 [entrez]
AID - S1885-5857(18)30297-4 [pii]
AID - 10.1016/j.rec.2018.05.029 [doi]
PST - ppublish
SO  - Rev Esp Cardiol (Engl Ed). 2019 Aug;72(8):608-615. doi: 
      10.1016/j.rec.2018.05.029. Epub 2018 Aug 2.